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Vitreous surgery. XIV. Complications from sclerotomy in 89 consecutive cases.

All patients were examined preoperatively and postoperatively by indirect ophthalmoscopy and biomicroscopy with a three-mirror lens. The average follow-up was eight months. Our technique of sclerotomy consisted of an incision parallel to the limbus, measuring 1.5 times the diameter of the surgical instrument. The pars plana location was always verified with transillumination. A mattress suture over the lips of the sclerotomy was used to prevent any leakage during the procedure. The intraoperative complications included ciliary body laceration (1%), retinal tears (8%), and vitreous base incarceration in the wound. The postoperative complications consisted of retina dragged into the wound (4%), vitreous tract left by the instrument (6%), neovascular ingrowth (6%), and external symptoms from the Dacron (32%) or polyglycolic acid (5%) suture. The rate of complications is considered low for such high-risk surgery.

Ciliary Body

Interface radiation dosimetry in mandibular reconstruction.

When a beam of radiation crosses the interface between two substances, secondary electrons are generated. This results in enhancement of the absorbed dose of radiation roughly proportional to the difference in atomic numbers. Interfaces are created in reconstruction of the mandible with implantable trays containing hematopoietic bone marrow and cancellous bone chips. Radiation was measured in tissue-equivalent material surrounding mandibular tray implants of titanium, vitallium, stainless steel, and Dacron/polyetherurethane. The absorbed dose was enhanced by 29% to 36% adjacent to the metallic trays; 1% dose enhancement was noted adjacent to the Dacron/polyetherurethane tray. We conclude that, when radiation therapy is necessary following mandibular reconstruction, homogeneity of dose is maintained and local soft-tissue reactions to excessive irradiation may be avoided by using a nonmetallic tray.

Biocompatible Materials

Crossover femorofemoral grafts followed up five years or more. An analysis.

Crossover femorofemoral grafts continue to provide satisfactory long-term patency with low morbidity and mortality in the treatment of unilateral atherosclerotic iliac artery occlusion. In our series of patients, early failures were primarily a result of the inability to provide adequate runoff for the graft, and late failures were due to progressive atherosclerotic involvement of runoff vessels. Clear-cut progression of the atherosclerotic process in the donor iliac artery segment has not been observed in this series. In fact, there is evidence that suggests that this process may have been retarded when compared with other types of reconstructive procedures. There is a noticeably late mortality (33%) due to other disease processes and associated cardiovascular disorders. These facts continue to support the application of crossover femorofemoral grafts in the surgical treatment of unilateral atherosclerotic illiac artery occlusions.

Adult

The natural history of bilateral aortofemoral bypass grafts for ischemia of the lower extremities.

Analysis of the immediate and long-term results in 180 patients undergoing aortofemoral bypass grafts for occlusive disease of the lower extremities showed the immediate graft limb patency in 360 graft limbs to be 99.2%. The cumulative ten-year graft limb patency was 66%. Factors associated with thrombosis of the graft limb revealed correlations for localized atherosclerotic disease of either the profunda femoris artery or the tibial trifurcation vessels. The highest correlation for graft limb thrombosis was with simultaneous lesions involving both the profunda femoris artery and tibial trifurcation vessels. The acute lower extremity salvage rate was 94%, and the ten-year cumulative extremity salvage for legs at risk of amputation was 85%. Postoperative symtpoms correlated well with patency. Overall operative mortality was five patients out of 180 (2.5%).

Adult

Evaluation of endarterectomy for aortoiliac and aortoiliofemoral occlusive disease.

During the past 11 years, 180 patients with aortoiliac and aortoiliofemoral occlusive disease were treated exclusively by endarterectomy. There were 59 patients in the former group and 121 patients in the latter group. A standard method of aortoiliac endarterectomy was applied to all patients. However, when disease extended to the external iliac and common femoral arteries, the eversion endarterectomy proved to be an invaluable technical aid. Cumulative patency rates to 11 years for the aortoiliac group was 85.7%, and for the aortoiliofemoral group it was 90.6%. Our results suggest that endarterectomy is the procedure of choice for the management of obilterative disease in the aorta, iliac, and femoral arteries.

Adult

Host response to implanted dacron grafts. A comparison between mesh and velour.

Segments of open Dacron mesh grafts were subcutaneously implanted in rats and harvested for a period of up to 12 weeks after operation at serial intervals. The gross and histologic events of the host response to the external surface were compared to that of segments of low-porosity Dacron velour implanted in a similar fashion. Mature collagen, generously vascularized with new capillaries, was noted throughout the mesh within three to four weeks, while a tightly bonded inner fibrous layer had formed from the surrounding tissues. Major segments of velour floated in amorphous caseous material for up to five weeks. These pools of debris with their concomitant inflammatory response slowly resolved during a ten-week period. This prolonged healing may contribute to eventual graft closure by progressive fibrosis and extrinsic contracture.

Animals

Filtration characteristics of polyester mesh (Pall) micropore blood transfusion filter.

Stored human blood of varying age was passed through polyester mesh (Pall) micropore blood transfusion (pore size, 40 mu). Passage through the filter resulted in decreased screen filtration pressure (SFP) of the blood and increased filter weight. Mumerous microaggregates were removed, but SFP did not return to normal after filtration. On the basis of this research, we conclude that polyester mesh micropore blood transfusion filters are not as effective as Dacron wool (Swank) transfusion filters in removal of micro-aggregates from stored human blood. If a polyester mesh filter must be used, it is recommended that once occlusion of the filter has occurred, the filter should then be discarded and another inserted.

Blood Preservation

Failure of ultralightweight knitted Dacron grafts in arterial reconstruction.

We have observed 11 cases in which the use of the ultralightweight knitted Dacron arterial graft made by the United States Catheter and Instrument Co. (USCI) was complicated by Interstitial hemorrhage dilation, or both. Although the incidence and specific cause of failure of this graft are unknown, we have discontinued its use on the basis of this experience.

Adult

Massive bleeding from a ruptured superior mesenteric artery aneurysm duodenum.

A traumatic false aneurysm of the superior mesenteric artery resulting from a gunshot wound five years previously, caused massive hemorrhage into the second portion of the duodenum. Dissection, resection, and end-to-end anastomosis was successful in controlling bleeding into the gastrointestinal tract, but immediate postoperative angiography showed a reappearance of the aneurysm, and three months later, it bled into the retroperitoneum. The patient underwent further resection and two subsequent reconstructions of the superior mesenteric artery, the first with a Dacron graft, which clotted, and the second with autologous saphenous vein, which was successful. Three years later, the patient is well. The case shows that adequate reconstruction of an arterial injury is best performed immediately after it is diagnosed.

Abdominal Injuries

Femorofemoral bypass graft in intra-aortic balloon counterpulsation.

Femorofemoral arterial crossover grafts were used in three patients to avoid or correct limb ischemia during intra-aortic balloon counterpulsation. In retrospec, these grafts should have been used in two earlier patients in whom the balloon was removed prematurely. They are applied to the femoral artery just distal to the site of insertion of the balloon or the the balloon access graft. Removal of the graft at the time of the balloon removal is optional.

Blood Vessel Prosthesis

Arm veins for peripheral arterial reconstruction.

The ipsilateral saphenous vein has become accepted as the best available material for femoropopliteal bypass and for arterial patch grafts as well as for visceral and cardiac bypasses. However, in a few patients, nonavailability or nonsuitability of the saphenous vein forces use of some other material. We report an experience with 32 operations using arm veins. Among the 11 long vein grafts, seven composite vein-Dacron or vein-vein grafts, and 14 vein patch grafts during the past six years, there were no infections or aneurysms and only nine thrombotic failures have been detected to date, to our knowledge. Our present indications are (1) ipsilateral saphenous vein is not available or is not suitable, (2) only a short graft or patch is needed and the saphenous vein may therefore be saved for the future, (3) to join to a saphenous graft or to a Dacron composite graft for additional length, and (4) to reconstruct an arm artery. Our experiences using cephalic and basilic veins confirms them as a useful source of autogenous material for arterial reconstruction.

Adult

Successful simultaneous renal transplantation and abdominal aortic aneurysmectomy.

At the time of related donor renal transplantation, a 49-year-old man with chronic glomerulinephritis was found to have a large fusiform aneurysm involving the internal and external iliac arteries, the abdominal aorta, and both common iliac arteries. Transplantation and abdominal aneurysmectomy using a standard Dacron bifurcation graft were successfully carried out. This patient has had no associated complications and is currently five years after transplantation and aneurysmectomy, with excellent renal function. It is believed that transplantation may now be offered to an older age group of patients with end-stage renal disease in whom atherosclerosis wll have developed as a natural process of aging.

Aneurysm

Multiple aneurysms in dacron velour graft.

Fomation of an aneurysm in a Dacron graft is a rare complication. It usually occurs within two years from operation. Most cases take the form of a generalized dilation. Multiple saccular aneurysms developed in a patient with a Dacron velour graft. The cause of the complication is not always clear, but multiple defects in the construction of the Dacron graft seemed the most likely cause in this case.

Aneurysm

Common bile duct obstruction associated with a dacron H-graft portacaval shunt.

An unusual patient had ascending cholangitis secondary to common bile duct obstruction by stones and a Dacron graft previously utilized in the performance of an H-graft portacaval shunt. Erosion of this foreign body into the common bile duct appeared to be secondary to bacterial contamination of the graft and direct contact of the foreign material with the biliary tree.

Cholangitis

Increased pulmonary arteriovenous shunting in humans following blood transfusion. Relation to screen filtration pressure of transfused blood and prevention by Dacron wool (Swank) filtration.

Transfusion through standard filters to dogs of stored blood containing microaggregates results in an increase in pulmonary arteriovenous shunting (Qs/Qt) and a decreased diffusion capacity of the lung for O2. These effects are due to microemboli that pass the filters and are prevented by use of Dacron wool (Swank) micropore transfusion filters. It was the purpose of this study to determine whether alterations in pulmonary shunting occur in humans following transfusions of stored blood through standard transfusion filters. In eight patients transfused over 20% of blood volumes through standard filters, Qs/Qt and alveolar-arterial O2 tension differences increased significantly. These changes did not occur in patients transfused comparable amounts of blood through Dacron wool (Swank) filters or in patients transfused less than 20% of blood volumes. A direct correlation was found between the absolute percent change in Qs/Qt and the quantity of microaggregates passing the filter and present in the transfused blood. It is concluded that removal from stored blood of microaggregates by administration of the blood through effective micropore transfusion filters prevents an increase in Qs/Qt caused by administration of such material.

Adult