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In vitro fertilization and birth after ultrasonically guided transurethral aspiration of oocytes.

We have described an in vitro fertilization and embryo transfer accomplished by ultrasonically guided transurethral transvesical oocyte aspiration. Follicular aspiration using ultrasonography is a suitable alternative to traditional laparoscopic methods, and may have several advantages, including avoidance of surgical and general anesthesia complications. Further experience with this technique will clarify the benefits and/or risks, and this work is continuing.

Biopsy, Needle↗

Clinical outcome of 285 Medpor grafts used for craniofacial reconstruction.

Porous polyethylene (Medpor) is an alloplastic material worldwide used for craniofacial reconstruction. To evaluate complications and risk factors associated with this synthetic graft, a retrospective study was performed. A series of 285 Medpor grafts were placed in 187 patients. Age, sex, diagnosis at admission, site, type of surgical insertion, type of fixation, and outcome (no complications, anesthesia, exposure, infection, and implant remodeling and removal) are considered. By means of univariate and multivariate analyses, we detect variables most associated with poor outcome. Univariate analysis showed that graft "survival" curves stratified according to (1) diagnosis at admission and (2) site are statistically significant. Subsequently, a Cox analysis was performed: both variables are also predictors of graft outcome. Porous polyethylene is a reliable alloplastic material that can be satisfactory used for craniofacial reconstruction. However, some sites (i.e., nose, maxilla, and ear) and diagnosis at admission (i.e., syndromic patients previously operated) are related to an higher risk of implant failure.

Adolescent↗

Cesarean section and maternal mortality in Sweden 1973-1979.

During the years 1973-79, 704732 births took place in Sweden and 63 075 cesarean sections (CS) were performed. Within the study period there were 20 maternal deaths associated with delivery or puerperium. Thirteen of these patients were delivered by CS and 7 by the vaginal route. The hospital records of the 13 deaths associated with CS were closely analysed and it was found that 5 of the patients were critically ill before the beginning of surgery, and the CS per se was not responsible for these deaths. The 8 remaining maternal deaths gave a corrected (cesarean-attributed) maternal mortality rate of 12.7/100 000 cesarean deliveries. For vaginal deliveries the mortality rate was 1.1/100 000 deliveries. Thus, the risk of maternal death from CS in Sweden was twelve times as high as that from vaginal parturition. All maternal deaths except one, associated with CS, occurred after emergency operation. No deaths were ascribable to anesthesia complications. The most common causes of death after CS were pulmonary embolism, amniotic fluid embolism, coagulopathy and peritonitis. Time trends in the causes of maternal death in Sweden are discussed.

Adult↗

A review of the effects of trace concentrations of nitrous oxide on performance and related health problems in medical and dental personnel.

Nitrous oxide has been used as an anesthetic for 100 years by the health care profession. Until recently, it has been considered safe from the standpoint of the patient. There have been less physical impairments and anesthesia complications with this agent than others. However, evidence has been accumulating that long term exposure to trace amounts of nitrous oxide could have a detrimental effect on personnel administering the anesthetic or working in close proximity to it. Chronic exposure to nitrous oxide has been implicated in causing liver and kidney damage, spontaneous abortions and birth defects along with impairment of short-term memory, coordination and hearing among those exposed. The author briefly reviews some of the evidence that led to the NIOSH criteria document on the occupational exposure to waste anesthetic gases and vapors.

Anesthesiology↗