PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Diverticulum, Colon”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 361 records · Page 20Linked to original sources
PubMedDate not supplied

Non-absorbable antibiotics in the treatment of diverticular disease of the colon.

Diverticular disease of the colon is a common health problem in western societies. Most patients with colonic diverticula are asymptomatic; it has been estimated that only 20% of individuals harboring diverticula will develop symptoms and signs of illness and a minority will develop major complications. Medical treatment of diverticular disease is aimed to the relief of symptoms and to prevent inflammatory complications. High fiber diets and antispasmodics are widely used in the treatment of uncomplicated diverticular disease although their real efficacy has not been fully elucidated. Antibiotics are used to treat major inflammatory complications of diverticular disease but apparently there is no rationale for their use in uncomplicated disease where an inflammatory component is, by definition, excluded. However two recent papers suggest a possible role of rifaximin, a broad-spectrum poorly absorbable antibiotic, in the management of mild acute diverticulitis and in obtaining symptomatic relief in patients with uncomplicated disease. Prospective studies with an adequate sample size per group of treatment are needed to assess the efficacy of cyclic long term administration of poorly absorbable antibiotics in preventing major complications of diverticular disease.

Bacterial Infections↗
PubMed1992

Diverticular disease of the colon in black Africa.

Diverticular disease of the colon, previously believed to be rare among Africans, is now an emerging disease entity in many areas of the African tropics. Fifteen patients, the majority of whom were overweight (73%), under 50 years of age (73%) and who have remained on the bulky diet traditional to much of Africa, are reported. The findings suggest that factors previously uncommon in the area may now be operating to cause the disease in the population, and the highly processed food products of the supermarkets may be an important contributor to the development of this new disease entity.

Adult↗
PubMed1992

Colonic diverticular disease in patients 40 years old or younger.

Diverticular disease in patients 40 years of age or younger has been described as rare but virulent. Previous studies, based on age, on diverticular disease are often confusing because of inexact definitions of the disease status. With these criticisms in mind, the authors studied 322 clinical records on patients admitted with a diagnosis of colonic diverticulosis or diverticulitis to the University of New Mexico Hospital and the Lovelace Medical Center. Of these patients, 285 had documented evidence of colonic diverticula with only 6 per cent of these being 40 years of age or younger. The criteria for acute diverticulitis were met by 86 patients, 17 of whom were 40 years of age or younger. The younger group had disproportionately more men, particularly Hispanics. The authors conclude that acute diverticulitis is more common in the young than suggested by previous reports, but the behavior of the disease is not distinctive.

Acute Disease↗
PubMed1952

Colonic diverticula.

Explore the source record for details and available documents.

Diverticulosis, Colonic↗
PubMed1992

Relationship between nutritional status indicators and length of hospital stay for patients with diverticular disease.

The length of a patient's stay in a hospital is an indication of the patient's recovery rate. Length of hospital stay has also become an important economic factor for hospitals. This is especially true since 1983 as a result of implementation of the Prospective Payment System based on diagnosis-related groups. In this study, the results of routine laboratory tests of nutritional status were examined for relationships between nutritional status and the length of hospital stay. We conducted a retrospective analysis of 163 patients with diverticulosis and diverticulitis of the colon to determine which nutrition assessment parameters are sensitive in predicting recovery rate (length of hospital stay). We found that serum albumin level was negatively correlated with length of hospital stay. Women without gastrointestinal bleeding stayed an average of 20.1 +/- 8.5 days when serum albumin level was 30 g/L or less vs 11.2 +/- 10.5 days when it was greater than 30 g/L. Hemoglobin and/or hematocrit levels were also negatively correlated with length of hospital stay for this group. Women without bleeding stayed an average of 16.4 +/- 13.4 days when the hemoglobin level was 120 g/L or less vs 10.4 +/- 9.1 days when it was greater than 120 g/L. These results suggest that a patient's nutritional status upon admission has an effect on the length of hospital stay for patients with diverticular disease.

Diverticulitis, Colonic↗
PubMed2004

[A case of non-small cell lung carcinoma successfully treated with carboplatin and weekly paclitaxel under renal dysfunction].

A 73-year-old man was admitted to our hospital with productive cough and dyspnea. His chest X-ray and CT scan showed a mass lesion on the lower lung field, pleural effusion on the left side, metastatic lesion in the right lung, and multiple metastases in the liver. The diagnosis was non-small cell carcinoma of the lung. Unfortunately, he had suffered from chronic nephritis; his creatinine level was 2.1, and his creatinine clearance was 29 ml/min. He received 4 courses of combined chemotherapy of carboplatin (AUC 5, day 1) and weekly paclitaxel (60 mg/ m2, day 1, 8, 15) every 4 weeks. His subjective symptoms as side effects were mild except for accidental melena due to colon diverticulum. Almost all lesions identified at admission were regressed by the chemotherapy. Although renal dysfunction often prevents patients with lung cancer from receiving systemic chemotherapies, in this case the combined chemotherapy of carboplatin and weekly paclitaxel proved to be a relatively safe and effective therapy for those patients with renal dysfunction.

Aged↗