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Femoral head vitality at reoperation for femoral neck fracture complications.

In seven patients suffering redisplacement, nonunion or segmental collapse after nailing of femoral neck fractures, subsequent changes in the vitality of the femoral head were studied with tetracycline labeling and 99mTc-MDP scintimetry. At reoperation (total hip arthroplasty), the femoral heads were extracted and sawn into slices which were then analyzed. Vitality before nailing was totally lacking (tetracycline labeling) in one case (nonunion), and in the remaining cases moderate reduction was seen, most pronounced in the apical part of the head. In all cases, scintimetry 1-2 weeks after nailing showed reduced femoral head uptake of 99mTc-MDP, but scintimetry some hours before reoperation showed increased femoral head uptake. Isotope analysis of the slices from the extracted femoral heads showed marked reduction of uptake in the apical part of the head, moderate reduction in the distal and anterior parts, and satisfactory uptake in the posterior part of the head and the foveal region, though with individual variations. It was concluded that there is a genuine increase in uptake (revascularization) later in the course in postoperatively avascular heads, and that the apical part of the femoral head sustains the most pronounced vascular damage in femoral neck fracture and is probably the slowest to revascularize.

Aged↗

Bone density distribution and gender dominate femoral neck fracture risk predictors.

OBJECTIVE: To determine whether regional characteristics of the proximal femur could discriminate between a group of patients who had just sustained a first low-trauma femoral neck fracture (n=50) from a group of healthy volunteers (n=123). DESIGN: The application of an integral bone measurement (dual-energy X-ray absorptiometry) in conjunction with a volumetric cancellous bone density measurement (quantitative computed tomography) to the proximal femur in vivo provided an estimate of the contribution of the spatial distribution of bone density to hip fracture risk prediction. RESULTS: The primary finding of this study was a significant difference between male and female hip fracture risk predictor variables. In men with femoral neck fracture, a significant decrease in bone density throughout the proximal femur was observed. In women with femoral neck fracture, a combination of local bone deficits (significant decrease in cancellous bone at the site of fracture, and a decrease in cortical bone at the site of impact) and significantly larger proximal femur dimensions (femoral neck and head widths) was evident. CONCLUSIONS: These results imply that effective hip fracture prevention strategies may require separate approaches for men and women. Screening programs for diminished bone density at the proximal femur have proved effective in previous studies. An approach which includes examining these local bone characteristics may further improve our ability to accurately determine hip fracture risk in vivo.

Absorptiometry, Photon↗

Femoral neck fractures--two populations.

A survey of 128 patients with femoral neck fractures has emphasised the difference in physical condition and clinical behaviour between those with cervical fractures and those with trochanteric fractures. The latter group of patients manifest advanced biological ageing and present a greater health care problem. Maintenance of mobility in the elderly may alleviate this situation.

Age Factors↗

A femoral neck fracture model in rabbits.

A technique was developed to create a reproducible femoral neck fracture in vitro using 5-month-old JW/CSK series male rabbits. Force attenuation of a newly developed damping material was also evaluated using this model. Ten pairs of the femora with smaller deviations in length and weight were harvested and cleaned of soft tissue. Either a right or left of each pair of the specimens was randomly selected and put into either the control or the experimental group, both of which contained equal numbers of the right and left femora. The specimens were attached to an L-shaped plate and embedded in a resin from the proximal diaphysis to the distal end so as to maintain a consistent position of the femora. They were mounted and fixed on a pedestal slanted in the coronal plane at 20 degrees. The impact load testing was conducted using an impact mallet dropped from a height of 3 cm. The impact load was applied onto the femoral head. To the specimens in the experimental group, attenuated impact forces were loaded through the damping material, but those in the control group were subjected to forces directly transmitted without the material. All the impact testing was performed in a temperature and humidity controlled chamber. All of the femoral specimens exposed to the direct impact forces (controlled group) sustained fracture at the neck. The fracture line passed from the base of the femoral head laterally and to the calcar area just proximal to the minor trochanter medially. The location of each fracture line was almost identical among the specimens. None of the specimens that were exposed to the impact force through the damping material (experimental group) sustained fracture macroscopically and roentgenographically.

Animals↗

Total hip arthroplasty for acute femoral neck fractures using a cementless tapered femoral stem.

The purpose of this study was to evaluate the osseointegration potential and implant-related complications of cementless total hip arthroplasty with a titanium alloy collarless, tapered, wedge-shaped femoral stem with a proximal circumferential plasma-spray coating in patients with acute hip fractures. The cohort consists of 85 patients with a mean age of 78.1 years. The mean duration of follow-up was 3.8 years. Total hip arthroplasty conferred significant improvement in function for all patients. All femoral components were stable with evidence of bone ingrowth (84 hips) or fibrous fixation (1 hip). Mild thigh pain was present in 3 patients. The complications included dislocation (3 cases), intraoperative femoral fracture (2 cases), and periprosthetic femoral fracture in the postoperative period (1 case). There was one reoperation for revision of the femoral component in the patient with a periprosthetic fracture. There were 25 (29%) deaths. Cementless total hip arthroplasty using a tapered proximally coated femoral stem is a viable option for the treatment of a displaced hip fracture and preexistent arthritis.

Aged↗

[Femoral neck fracture complicating orthopedic reposition of a dislocated hip: four cases].

Posterior dislocation of the femoral head with fracture is an exceptional hip injury. Emergency reduction is required. Reposition into the acetabular cavity of the dislocated femoral head may not be feasible. Irreducibility, instability, and more rarely accidental fracture of the femoral neck may also occur. We encountered this latter complication in four patients and report here its frequency and mechanism and propose preventive therapeutic measures. Seventy dislocations and fracture-dislocations of the hip were treated in our unit from March 1997 to February 2003. Among these cases, fourteen hip dislocations were complicated by femoral head fractures. Fracture of the femoral neck occurred during reduction in four. All four cases occurred in men, mean age 49.7 years, who were traffic accident victims (drivers or passengers). There were two Pipkin IV fracture-dislocations and two Pipkin II. The first reduction, achieved under general anesthesia in an emergency setting, was performed by an orthopedic surgeon in one patient and a general surgeon in three patients. Arthroplasty was used to treat the femoral neck fracture in three patients and pinning in one. We reviewed retrospectively the clinical and imaging data before and after reduction. Sub-capital fracture situated 4.0 cm (mean, range 3.5-4.5 cm) from the lesser trochanter occurred in all four cases. The head remained attached above and posteriorly to the acetabulum and was rotated less than 90 degrees . The fragment remaining in the acetabulum was displaced in two cases. In one patient, the fracture-dislocation of the head was associated with a fracture of the posterior rim of the acetabulum. This complication appears to result from an abrupt inappropriate reduction movement. The neck fracture would occur when capsulomuscular retention of the femoral head is associated with a head defect which catches on the rim of the acetabulum during the reduction movement. Neck fracture during reduction of traumatic hip dislocation is a serious complication. Prevention of this iatrogenic event requires a slow, progressive reduction limiting the trauma to a minimum; first intention open surgery may be required in selected cases.

Accidents, Traffic↗

Femoral head vitality in femoral neck fracture after hook-pin internal fixation.

Femoral head vitality was evaluated by tetracycline labeling and 99mTc-MDP scintimetry in 317 femoral neck fractures before and after internal fixation with two hook-pins. The preoperative vitality was about the same as that observed by others using comparable methods. The postoperative vitality was reduced in five of 81 undisplaced fractures and in 76 of 236 displaced fractures. These data would predict a rate of avascular healing complications of 7% in undisplaced and 32% in displaced fractures treated with hook-pins.

Adult↗

Femoral neck fracture following groin irradiation.

PURPOSE: The incidence and risk factors are evaluated for femoral neck fracture following groin irradiation for gynecologic malignancies. METHODS AND MATERIALS: The radiation therapy records of 1313 patients with advanced and recurrent cancer of the vagina, vulva, cervix, and endometrium, treated at the Mallinckrodt Institute of Radiology from 1954 to 1992, were reviewed. Median follow-up was 12.7 years. From this group, 207 patients were identified who received irradiation to the pelvis and groins with anterposterior-posterior anterior (AP-PA), 18 MV photons. Data were reviewed regarding irradiation dose to the femoral neck and other presumed risk factors including age, primary site, stage, groin node status, menopausal status, estrogen use, cigarette use, alcohol consumption, and osteoporosis. RESULTS: The per-patient incidence of femoral neck fracture was 4.8% (10 out of 207). Four patients developed bilateral fractures. However, the cumulative actuarial incidence of fracture was 11% at 5 years and 15% at 10 years. Cox multivariate analysis of age, weight, and irradiation dose showed that only irradiation dose may be important to developing fracture. Step-wise logistic regression of presumed prognostic factors revealed that only cigarette use and x-ray evidence of osteoporosis prior to irradiation treatment were predictive of fracture. CONCLUSION: Femoral head fracture is a common complication of groin irradiation for gynecologic malignancies. Fracture in our database appears to be related to irradiation dose, cigarette use, and x-ray evidence of osteoporosis. Special attention should be given in treatment planning (i.e., shielding of femoral head/neck and use of appropriate electron beam energies for a portion of treatment) to reduce the incidence of this complication.

Adult↗

[Anterior femoroacetabular impingement after healed femoral neck fractures].

OBJECTIVES: To describe anterior femoroacetabular Impingement (AFAI) as a cause of persistent painful loss of motion and progressive joint-destruction in patients with a healed femoral neck fracture, and to evaluate results after its surgical treatment. METHODS: Eleven patients with groin pain elicited by motion and exertion following a healed femoral neck fracture were diagnosed clinically, by conventional radiographs and radial Arthro MRI with AFAI. During surgical subluxation or dislocation of the hip joint the impingement was visually verified and eliminated by re-shaping the anterior contour of the head-neck-junction. RESULTS: All patients presented a flat contour of the anterior head-neck-junction causing a cam-type impingement with subsequent damage of the anterior-superior acetabular cartilage adjacent to the rim. These chondral changes result from the repetitive compression and shear forces between the flattened head-neck junction and the acetabular cartilage in flexion and internal rotation. At five year follow-up a clear improvement of the symptoms was observed without any signs of progressive joint destruction. CONCLUSION: When chronic pain after a healed femoral neck fracture without necrosis of the femoral head occurs, the possibility of an AFAI caused by retrotorsion of the proximal fragment should be taken into consideration. The symptoms of AFAI can be relieved by surgical correction of the femoral head-neck-offset. The existing damage of the acetabular cartilage originated by the impingement at the time of surgery can hardly be improved. Therefore anatomical fracture reduction should be performed in order to prevent the development of osteoarthritis. Pre-existing deformities of the joint should be treated at the time of operative fracture treatment.

Acetabulum↗

Stability of internally fixed femoral neck fractures augmented with resorbable cement. A prospective randomized study using radiostereometry.

BACKGROUND AND AIMS: Internal fixation of displaced femoral neck fractures is associated with a high risk for complications such as non-union or avascular necrosis. A stable fracture fixation can improve prognosis although stability is often counteracted by weak osteoporotic bone. The aim with this study was to evaluate whether augmentation with resorbable calcium-phosphate cement could improve fracture stability during the early period after surgery as shown in biomechanical studies. MATERIAL AND METHODS: 40 ambulatory patients with a displaced femoral neck fracture were randomized to treatment with cannulated screws alone (controls) or screws combined with calcium-phosphate cement for augmentation (augmented). All patients were allowed unrestricted weight bearing after surgery. Fracture movement was measured with radiostereometry (RSA) at 1 and 6 weeks. RESULTS: At 1 week the augmented fractures had moved on average 1.9 +/- 1.0 mm while movement in the controls was 5.5 +/- 3.4 mm (p < 0.0001). The average total movement at 6 weeks was 6.9 +/- 2.9 mm and 10.9 +/- 5.1 mm, respectively (p < 0.005). Varus angulation and distal migration of the femoral head were the most common movements for both groups although augmented fractures had moved significantly less at both 1 and 6 weeks. There were no significant differences in angulation between groups around the longitudinal and transversal axes or in migration along the transverse or sagittal axes. CONCLUSION: Augmentation with calcium-phosphate cement improved the stability of internally fixed femoral neck fractures during the first six weeks after surgery, with improvement being less pronounced at six weeks compared with at one week.

Aged↗

Intertrochanteric osteotomy for failed internal fixation of femoral neck fracture.

Thirteen patients with failed internal fixation of the femoral neck were treated with valgus intertrochanteric osteotomy performed by one surgeon from 1987 to 1995. The patients ranged in age from 18 to 59 years. The interval from injury to osteotomy ranged from 4 to 54 weeks. With an average followup of 25 months (range, 9-42 months), the femoral neck fracture healed in all patients. Twelve patients returned to being fully weightbearing without pain. The average limb shortening was improved by 1 cm. Seven of eight patients who were employed before their injuries returned to the same occupations. Femoral head collapse because of avascular necrosis developed in one patient 18 months after surgery and return to full activities and in a second patient shortly after the osteotomy. These two patients now have an arthroplasty. The remainder of the patients have done well without requiring additional surgery. Harris hip scores and Short Form 36 Health Status Survey outcome scoring were available to verify the results in 10 patients.

Adolescent↗

Femoral neck fracture: a preventable phenomenon?

The purpose of this paper is to examine the problem of femoral neck fracture in the elderly New Zealand citizen, and to consider the prospects for prevention. Data are drawn chiefly from the Accident Compensation Corporation's claims data base, which has enabled identification of the mechanism of accident associated with such fractures. The data reveal a relative preponderance of femoral neck fracture in females of advanced age. In this group, the typical accident sequence is found to be mundane, 84% of victims falling to the ground without involvement of external agency. It is concluded that the resulting fractures are largely attributable to the heightened vulnerability of the subject as opposed to the magnitude of the blow. Hence, an appropriate intervention strategy should be aimed at strengthening the bone structure of individuals at risk. The practicability of this approach is discussed with particular reference to calcium and hormonal supplements. It is noted that cost and other factors make identification of a high risk sub-population desirable. Modern methods of bone density measurement have enhanced the feasibility of this procedure.

Age Factors↗

Prosthetic replacement in femoral neck fractures.

Despite refinement of the guidelines for the use of an endoprosthesis in the management of femoral neck fractures and for the use of bone cement, no universally accepted treatment regimen currently exists. In order to collect statistically significant data about the "unsolved fracture," prospective studies from several centers must be undertaken. However, until such data are available, we submit the following conclusions about the patient with a cemented endoprosthesis for a femoral neck fracture. The early results are satisfactory--patients experience relatively little pain. Femoral fixation is enhanced--loosening occurs less frequently. The complications of prosthetic replacement are not increased by the use of cement fixation.

Femoral Neck Fractures↗

The displaced femoral neck fracture. Internal fixation versus bipolar endoprosthesis. Results of a prospective, randomized comparison.

The displaced femoral neck fracture poses difficult decision-making issues for the orthopedic surgeon. Young patients frequently require a rapid open reduction and rigid internal fixation in the face of multiple associated injuries. Elderly patients present the typical decision dilemma of internal fixation versus arthroplasty. Consecutive, randomized, prospective series of cases for evaluation of alternatives in the treatment of this difficult fracture are lacking. Between 1982 and 1984, 34 elderly patients with displaced femoral neck fractures were randomized to open reduction or hemiarthroplasty study groups. Although the surgical risks are relatively high, two-year observations showed better functional results in the cemented hemiarthroplasty group.

Aged↗

[Medial femoral neck fracture. Controversies in treatment].

The treatment of the medial femoral neck fracture remains controversial until today. The goal of this paper is therefore, based on the literature, to show guidelines for optimal treatment: conservative treatment vs. operation, osteosynthesis vs. prosthesis, timing for osteosynthesis, open vs. closed reduction, choice of implant for osteosynthesis, postoperative treatment (weight bearing vs. non weight bearing), Pauwels-Osteotomy vs. prosthesis in cases op pseudarthrosis, femoral head prosthesis vs. total hip arthroplasty, bipolar vs. monopolar femoral head prosthesis, choice of classification. Further we want to point out which statements are evidence based and where we need further investigation.

Arthroplasty, Replacement, Hip↗

Stroke, a major and increasing risk factor for femoral neck fracture.

BACKGROUND AND PURPOSE: Patients with stroke have up to a 4-fold increased risk of hip fracture because of their high incidence of falls and loss of bone mass in the paretic side, ie, hemiosteoporosis. The purpose of this study was to investigate the prevalence of previous stroke among patients with femoral neck fracture. METHODS: The study included all 568 patients, aged >/=65 years, who underwent surgery for femoral neck fracture in 1980, 1983, 1987, 1993, and 1997 at the orthopedic clinic of Umeå University Hospital, Umeå, Sweden. RESULTS: The prevalence of previous strokes ranged from 16.4% to 38.5% (P<0.001); this finding is only partly explained by the increased incidence of stroke in the corresponding population, and there was no significant increase in the overall incidence of femoral neck fracture. Fractures occurred 5.4+/-6.4 years after stroke (median 2.9 years, range 0 to 33 years). In stroke patients with unilateral stroke and persisting paresis at the time of fracture, 62.5% had their fracture on the paretic side (P=0. 034). Survival was significantly reduced in patients with previous stroke (P<0.001). In patients previously independently mobile, 69.2% with no previous stroke and 38.1% with previous stroke were still mobile at discharge from the orthopedic unit (P<0.001). CONCLUSIONS: Attention must be focused on stroke as a major and increasing risk factor for femoral neck fracture and also on the poor postfracture outcome and reduced survival of these patients. Prevention of poststroke fractures is necessary and is aimed at reducing the risk of poststroke fall and preventing the development of hemiosteoporosis.

Aged↗