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[Characteristics of the K(+)-ion transport in the rat intestine following the use of natural zeolites as food additives].

Effects of zeolites as a food supplement have been studied on Wistar rats both in vivo perfusion experiments in the jejunum and distal colon and Rb fluxes through intestinal wall in the Ussing chamber. It has been found that zeolites decrease the K+ absorption and stimulate K+ secretion in the gut. This effect was due to inhibition of the apical N(+)-K(+)-ATPase and ouabain-sensitive Na(+)-independent K(+)-ATPase as well as the activation of the basolateral N(+)-K(+)-ATPase.

Animals↗

[Use of food additives in a multimodal treatment of disseminated pulmonary tuberculosis].

Effects have been studied of multimodality treatment on the function of external breathing in patients with disseminated pulmonary tuberculosis using food additives Trace Minerals. Positive dynamics has been recordable of changes in indices for forced lung vital capacity, minute oxygen consumption, both prior and after loading, and maximum volume speed (MVS75) before loading. The obtained data are indicative of the efficacy of using vitamin-mineral additives Trace Minerals evidenced by improvement in bronchial patency and normalization of ventilation-and-perfusion relations in patients with destructive forms of pulmonary tuberculosis.

Adult↗

Changes in lipid composition of Escherichia coli resulting from growth with organic solvents and with food additives.

Cells of Escherichia coli contain an altered fatty acid and phospholipid composition when grown in the presence of sublethal concentrations of a variety of organic solvents and food additives. The diversity of compounds examined which caused these changes indicates that no single catabolic pathway is involved. Many of the observed changes are consistent with the hypothesis that cells adapt their membrane lipids to compensate for the presence of these compounds in the environment. Both sodium benzoate and calcium propionate caused the synthesis of unusual fatty acids.

Escherichia coli↗

[Food additives as a cause of medical symptoms: relationship shown between sulfites and asthma and anaphylaxis; results of a literature review].

OBJECTIVE: To determine if a causal connection exists between food additives and various medical complaints. DESIGN: Literature study. METHOD: Medline over the period January 1966-January 1999 was searched for articles on the following substances not containing protein and lactose: monosodium glutamate (MSG), sulfites, azo-dyes (tartrazine, sunset yellow, azorubin, amarant, cochineal red), benzoates, sorbates, butylated hydroxyanisole/butylated hydroxytoluene (BHA/BHT), parabens, cinnamon and vanilla, in combination with key words regarding food and side effects. Of those studies purporting to demonstrate an effect, only double-blind randomized placebo-controlled studies with oral challenge were assessed further, unless the complaint was anaphylaxis. Of studies not demonstrating an effect the design was assessed. RESULTS: Only for sulfites as causative agents of asthma and anaphylaxis, methodologically adequate studies demonstrating a causal connection could be found. For azo-dyes, benzoates, MSG, sorbates and BHA/BHT, no link with medical symptoms was demonstrable. For parabens, cinnamon and vanilla there were insufficient or inadequate data to justify a conclusion.

Anaphylaxis↗

[The mutagenic effects of sodium nitrite and monosodium glutamate used as food additives demonstrated by the Salmonella microsome test system].

In this study, the mutagenicity of sodium nitrite (an antimicrobial agent) and monosodium glutamate (a flavoring agent), which are widely used as food additives, have been evaluated. They were tested for mutagenicity in the Salmonella/microsome test system by employing plate-incorporation test in the absence and presence of rat-liver fraction, S 9. No mutagenic activity was seen for monosodium glutamate in the Salmonella/microsome test system by using the tester strains Salmonella typhimurium TA98, TA100, TA1535 and TA1538. Sodium nitrite was found mutagenic on S. typhimurium TA1535, whereas it was found weakly mutagenic on S. typhimurium TA100, in the presence and absence of rat-liver fraction, S 9.

Animals↗

Food additives.

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Coloring Agents↗