SEARCH · PubMed Health
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
An exceedingly rare tumor was found coincidentally in a young woman who had salpingectomy. The benign tumor was complex in nature and consisted of a lymphangioma and a well-encapsulated lipoma located in the mesentery of the small intestine. This tumor is compared with the similar ones mentioned so far in the literature.
One hundred and seventy one patients with mesentery tumors confirmed by surgery and/or pathology in five hospitals of Hubei Province from 1966 to 1986 are analyzed retrospectively. The main manifestations were abdominal pain, abdominal mass and emaciation. Cyst and leiomyomas were common in benign tumors. Malignant lymphoma, leiomyosarcoma and liposarcoma were predominant in malignant tumors. The morbidity, clinico-pathologic characteristics, diagnosis and differential diagnosis of this group of tumor are discussed.
A case of mesothelioma with a rare localisation (the mesentery root with growth around the small bowel and the destruction of the upper mesenteric artery) is described. Necrosis of the small bowel occurred after the operation with the subsequent peritonitis which resulted in death. Histologically, the tumor was an epithelioid variant of mesothelioma of the tubulopapillary structure.
We report one case of mesenteric malignant fibrous histiocytoma, demonstrated by pain, abdominal mass and hypoglycaemic faintness. Ultrasound showed an heterogeneous mass, with liquid areas surrounded with echogenic trabeculations. A percutaneous aspiration under ultrasound guidance of the liquid collections demonstrated sero-sanguineous material. A computed tomography showed the mass to involve the upper small bowel mesentery; organic hypoglycaemic series suggested a mesenchymal tumor, the histologic type of which was only known by post-mortem examination of the specimen.
A technique for easy and bloodless dissection of fat laden intestinal mesentery, both small and large, has been described. This technique can also facilitate Roux-en-Y reconstruction in the obese patient.
In anesthetized rats, i.v. administration of adenosine (2.5 mg/kg/min) for 30 min caused reduction of mean systemic blood pressure. A significant decrease of blood flow was found in mesentery microvessels as well as dilation of arterioles and venules.
A 14-year-old girl was hospitalized with fever, jaundice, vomiting and right sided abdominal pain. A laparotomy was performed because of muscular defence and ascites. There was a mass of enlarged red and blue colored lymph nodes in the mesentery of the lower ileum loop. The histologic diagnosis of HNL without granulocytic infiltration was made. A septic-toxic shock developed after surgery. Respiratory insufficiency necessitated the use of a respirator, and acute renal failure with oliguria made hemodialysis necessary. The dramatic clinical course of the illness and the localization of the affected lymph nodes in the abdomen are unusual for an HNL; the lack of granulocytic infiltration contradicts the clinical picture of a bacterial infection. Neither a bacterial nor a viral pathogen could be found. However, the patient had been treated with antibiotics before.
A case of leiomyomatosis of the colon and mesentery in a 35-yr-old man with several noninvalidating congenital malformations and multiple intracranial meningiomas is presented. The leiomyomatosis had been asymptomatic until 2 months before death, even though the lesions suggest a congenital disorder affecting the musculature of the bowel wall.
Insulin role in regulating the immunocompetent tissue structure was studied on experimental rats with alloxan diabetes. Tendency to a decrease in the mesenteric lymph node cortical area, accompanied by a fall in the small lymphocyte number, was observed. The lymphatic follicle area markedly diminished. The small lymphocyte and reticular cell content among cellular elements of the clear centers significantly augmented, whereas mitosis number and the percentage of mean and large lymphocytes decreased. Billroth's strand area diminished by one-third comparatively to that of the control. Simultaneously their number of plasma cells and small lymphocytes lowered. Therefore, alloxan diabetes is accompanied by a fall in the parameters of the thymus-dependent structural components of the mesenterial lymph nodes. Insulin deficit induces a decrease in the number of lymphocytes, capable of proliferation and diminishes their mitotic activity.
Suturing devices UO-40, UO-60 and NZhKA-60 supplied with silicon fixators of compression were used for suturing gastric and mesentery stumps. Silicon gaskets were later rejected into the stomach lumen. Silicon strips stitched by metallic clamps left in the abdominal cavity were found to cause neither inflammatory reactions nor scarry adhesions both in the nearest and remote periods after operation. It was not necessary to put even one thread ligature when ablating great portions of the intestine.
Structural changes and hemodynamic relations have been studied in the microcirculatory bed of the white rat small intestine mesentery during sex maturation (from the 3d up to the 10th week of the postnatal development). All calculations are performed regarding the mesenteric segment limited with two intestinal arteries, which is considered as an elementary microvascular module. Complication of the microcirculatory bed construction takes place at the expense of increasing number (nearly five-fold) of microvessels in the segment and increase of the capillary network density. The hemodynamic factor plays a certain role for stimulating the process of the capillary growth. The definitive structure of the mesenteric microcirculatory bed is completed by the 7th week. The main rearrangement of the microcirculatory system during the developmental process from a simple arterio-venular loop up to a complex microcirculatory bed with a branching capillary network is performed within the limits of the mesenteric segment.
The mesentery is a duplicature of the peritoneum consisting of loose connective tissue and covered on both sides by mesothelium. Rabbit V2 carcinoma cells implanted i.p. adhere to the mesenteric surface between contracted mesothelial cells. While invasion from these sites sets in, progressive changes of the connective tissue, reflecting fibroblast stimulation, become apparent and comprise multiplication of connective tissue cells, transformation of fibrocytes into fibroblasts, and enhanced production of fibrillar and nonfibrillar constituents of the extracellular matrix. Tumor invasion into this increasingly dense tissue proceeds in 2 ways. (a) Single cells penetrate into and locomote within the interior, where they divide and give rise to nodules which become surrounded by zones of tissue destruction. (b) Proliferation of surface-attached tumor cells results in the formation of nodules which, preceded by zones of tissue damage, extend into the interior. While evidence for lytic effects in the microenvironment of single tumor cells is lacking, degradation of the fibrillar extracellular matrix is regularly found around tumor nodules and indicates a collective lytic action achieved by tumor cells and, possibly, host cells. These morphological findings are discussed in relation to published bio- and histochemical data on spread of the V2 carcinoma.
Fluorescent microscopy combined with an assay of the intensity of nerve structure fluorescence was used to study adrenergic innervation of the rat mesentery and dura mater under immobilization stress. The adrenergic nerves were found to undergo morphofunctional changes over time. These changes were marked by a dramatic fall of noradrenaline fluorescence within the first immobilization hours, followed by rise at the 4th-6th hour of experiment. In prolonged immobilization, mediator activity of the adrenergic nerves remained under initial (control) level. The data obtained attest to the involvement of the peripheral adrenergic innervation in stressor response and in the adaptive mechanisms during immobilization.
A panniculitis isolated solely to the fat tissue of the mesentery is rarely encountered. Problems related to the diagnosis, therapy, and-patho-anatomical features of this polyetiological disease are presented. Based on the excellent response to antirheumatic therapy accompanied by a positive HLA B27, this case could be classified as a connective tissue disease.
Tranylcypromine (TCP), which can inhibit prostacyclin (PGI2) synthesis in vitro, has been shown to facilitate platelet aggregation in damaged cerebral arterioles of the mouse when given intraperitoneally (50 mg/kg) one hour before inducing aggregation. The same dose has no effect on platelet aggregation in damaged mesenteric arterioles. The present experiments used HPLC and GC/MS to analyze PG levels and show that 5 or 50 mg/kg TCP, given intraperitoneally one hour before sacrificing the mouse, moderately reduces the level of 6-keto-PGF1 alpha, the stable metabolite of PGI2, in incubated brain homogenates. This finding supports the hypothesis that TCP's enhancement of platelet aggregation in the brain was affected by a reduction in PGI2 levels. When 500 micrograms/ml TCP was added to the incubate of brain homogenate from mice given 50 mg/kg, PGE2 levels were reduced as well as the levels of 6-keto-PGF1 alpha. In incubated mesentery, the level of 6-keto-PGF1 alpha was also reduced by treating mice with 50 mg/kg TCP. The latter result failed to support the hypothesis that levels of mesenteric 6-keto-PGF1 alpha would be unaltered by TCP in parallel with the inability of TCP to alter platelet aggregation in mesenteric arterioles. Thus our data fails to support an overall hypothesis relating TCP action on platelet aggregation to its inhibitory effect on PGI2 synthesis. At the same time the data do not rule out such a relationship for mouse brain.
Film preparations of the mesentery were used for morphological study of cell reactions, connected with the delayed type hypersensitivity (DTH). Twenty-four hours after intraperitoneal injection of small doses of the streptococcal thermostable fraction (TST fraction) the guinea-pigs sensitized with streptococcal culture developed a more intensive, as compared with control animals, diffuse infiltration of the peritoneum with mixed type cells (lymphocytes, monocytes and polynuclear leukocytes) abundant in mononuclear elements. With TST fraction dose build up the infiltration demonstrated an abrupt increase in polynuclear leukocytes completely masking the monocytic reaction in some cases. Large aggregations of lymphocytes were seen in the prelymph sinuses accompanying blood capillaries and nervous stemlets. Detection in the peritoneum of cell reactions characteristic of DTH following the injection of certain doses of specific antigens and comparative simplicity of obtaining film preparations allow recommending the technique described for disclosing and experimental study of DTH to microbial antigens.
The authors studied nCHE activity in Pacinian corpuscles of the mesentery of adult cats and 14-day-old kittens. The localization of nCHE was performed on non-frozen sections in Karnovsky's method (1964) with inhibitor application. The nCHE activity was by means of reaction product deposits always localized on plasmic membranes of inner core lamellae and on the axon axolemma. On capsule lamellae no nCHE activity was found. In inner core cells of Pacinian corpuscles of adult individuals, owing to sporadic occurrence of organelles their relationship to nCHE activity failed to be established. It was possible only in Pacinian corpuscles of 14-day-old kittens, where organelle findings are substantially more frequent and furthermore the lamellae broader, which facilitates the localization of deposits on plasmic membranes. The nCHE activity was proved here on the rough endoplasmic reticulum and on vesicles of the Golgi complex. For the above-mentioned reasons Pacinian corpuscles of kittens are substantially more suitable for the ultrahistochemical localization of enzymes than those of adult cats. The difference in nCHE activity localization, as it was established by Idé and Saito (1980), is probably caused by the different preparation of sections for incubation (cryostat sections were used). The occurrence of nCHE isoenzymes with different binding to the membranes of inner core cells of the Pacinian corpuscle not only renders exact electron-microscopic localization more difficult but it also shows that, similarly as ACHE, nCHE is synthetized in the rough endoplasmic reticulum in soluble oligomeric form. Only after aggregation of these subunits is it bound to the membranous structures of the inner core. The reversibility of this process can explain the irregular findings of the precipitate, mainly on pinocytotic vesicles. The localization of nCHE on inner core cells supports the opinion that inner core lamellae of Pacinian corpuscles are formed by Schwann cells. The nCHE activity found on all inner core lamellae of Pacinian corpuscles from the axon to the capsule lamellae is further evidence for the nonexistence of a special zone of lamellae, the so-called outer core, between the inner core and capsule.
A rare case of primary myxoid liposarcoma of the mesentery was observed and a detailed description of the clinical case and the operation performed is presented. In conclusion the clinical and diagnostic aspects of such tumours are analysed with emphasis on the major anatomical and pathological features.