Methicillin resistance of Staphylococcus aureus and Staphylococcus epidermidis.
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Enzymatic patterns, antibiotic sensitivity, penicillinase, production, mercury ion resistance have been studied in St. saprophyticus strains in comparison with St. epidermidis, both isolate from urinary infections of hospital patients. The St. saprophyticus has shown to have a lower number of virulence factors, to be more sensitive to antibiotics and to have a lower potential epidemiological value.
A total of 20 different allergens extracted from various staphylococcal strains were studied in the delayed hypersensitivity reactions in experiments on guinea-pigs. The most intensive dermatoallergic reactions were observed after the injection of the cytoplasmic fraction, acidic and alkaline extracts; reactions to the allergen of Ando-Verzhikovsky were less pronounced. The cytoplasmic fraction and the allergen of ando-Verzhikovsky were more active in the reaction of leukocyte migration inhibition in the blood. Both common and individual allergenic components were detected. No correlation between the results of the immunochemical and allergological studies of staphylococcal extracts was revealed.