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PubMed1989

[Effectiveness of INH-rifampicin treatment of lymph node tuberculosis].

The efficacy of the therapy of tuberculous lymphadenitis using two drugs with bactericidal activity is described. In this localization, the tuberculous process implies tubercle bacilli only in limited quantity, and thus, in contrast to the requirements and recommendations for the treatment of pulmonary tuberculosis, the application of only two drugs with bactericidal activity is sufficient. The treatment of 128 patients with histologically confirmed tuberculous lymphadenitis consisted in daily application of isoniazid and rifampicin during 4 to 6 weeks, followed by an intermittent treatment with the same drugs for 6 to 9 months. The follow-up period was 7.5 years. Complete involution of the diseased lymph nodes was obtained in two thirds of the patients, partial involution in the remaining third. In one patient, a relapse occurred. The indications of this regimen are discussed.

Adult↗
PubMed2004

Tuberculosis of the cystic duct lymph node.

Tuberculosis of the cystic duct lymph node associated with cholelithiasis is rare. We report a case of a 40 year-old woman with this pathology. She presented with anorexia, biliary colic, postprandial fullness and fever. Imaging studies revealed cholelithiasis and several visible portal lymph nodes. Cholecystectomy was performed and histopathological examination showed tuberculosis of the cystic duct lymph node without affecting the gallbladder. The presence of gallstones and lymphadenopathy in computed tomography, associated with persistent fever and symptoms that resemble cholecystitis, should cause suspicion of tuberculosis. However, diagnosis is usually achieved by microscopic appearance of caseating granulomas and isolation of Mycobacterium tuberculosis. The treatment in this case consisted of cholecystectomy and antitubercular chemotherapy.

Adult↗
PubMed2006

Persistent mediastinal and axillary lymph node tuberculosis in a renal transplant patient with successful outcome.

Tuberculosis is an opportunistic infection that carries substantial morbidity and mortality in renal transplant recipients. We report here about a 21 year-old man with a living related renal transplant from his mother who developed persistent extra-pulmonary tuberculosis. The disease showed aggressive invasion to the axillary and mediastinal regions with abscess formations, despite standard antituberculosis treatment. During the course of the disease, immunosuppressive therapy was stopped, and the patient received extraordinary doses of multiple antituberculosis drugs. The patient then showed an uneventful course with good clinical and radiological responses.

Adult↗