Functional and adaptive changes in the vestibular apparatus in space flight.
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Clawed frog larvae (stages 45-46) that developed for 9 and 8 days beginning with the blastula and tail bud stages, respectively, in the weightless state were investigated. Scanning microscopy of the larval labyrinths did not reveal significant qualitative changes in the receptor and supporting cells of the maculae and in the otolith membrane. Determination of the electrolyte composition (Na, K, Ca, Mg) of the larval body showed no significant changes in the relative content of these elements. The morphometric examinations indicated an increase of the size of the utricular otoliths by 1.3 times as a result of exposure to weightlessness. There was a tendency for a greater asymmetry between the left and right otoliths in the same larva.
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A mathematical model is suggested of the biological system of angular stabilization in space relative to the local vertical using measures whose parameters are near to the parameters of the semicircular canals and otolithic organ of the man. On the basis of computer simulation for physiologically adequate external stimulations contribution of each of measures to the total process of angular stabilization is evaluated.
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