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Image quality control for digital mammographic systems: initial experience and outlook.

This report presents (1) a broad topical review and a tutorial of the possibilities for image quality control (IQC) with digital systems, and (2) results and initial experience for IQC with two commercial digital imaging systems, but with limited discussion on any particular method. Digital imaging systems used for mammographically guided digital stereotactic breast biopsy were evaluated extensively at the University of Arizona. Measurements were made of linearity, sensitivity, signal-to-noise ratio, and square-wave modulation. Images of phantoms such as the American College of Radiology Accreditation Phantom and the contrast detail mammography Phantom were evaluated as well as images of the x-ray source's focal spot. The evaluation also included the cathode ray tubes for the imaging systems. The data collected show that digital imaging systems have an important advantage over film-screen systems because they provide a digital signal as output that can be used for quantitative analysis. As a result, IQC can become a much more quantitative discipline than presently practiced, providing more information on the imaging systems under evaluation, and providing better control over their properties during actual operation.

Computer Terminals↗

Marked reduction and distinct patterns of eye blinking in patients with moderately dry eyes during video display terminal use.

PURPOSE: To analyze the spontaneous eye-blink rate (SEBR) and blinking pattern in patients with moderately dry eyes during video display terminal (VDT) use. METHODS: The SEBR of 30 patients with dry eye syndrome (median age 44.8 years, range 18 - 67 years) was measured using a computer-based video analysis system. Only complete eye blinks were recorded during 10 min of conversation, during initial VDT use and again after a preceding work period of 30 min. RESULTS: In comparison with SEBR during conversation (mean value 16.8 blinks/min, standard deviation 16.8 blinks/min) the SEBR significantly decreased during initial VDT use (6.6+/-4.8; P<0.001) and remained significantly decreased during re-measurement after 30 min (5.9+/-4.6; P<0.001). SEBR was not significantly different between initial VDT use and re-measurement after 30 min ( P=0.65). The SEBR was characterized by marked interindividual variability during conversation and VDT use. No significant correlation was found between SEBR (either during conversation or during VDT use), and the quality (tear break-up time) or quantity (Schirmer I test, Jones test) of the tear film. Typical blinking patterns were found to be (1). a relatively time-independent, irregular pattern, (2). an initial phase of 2-4 min with shorter inter-eye-blink intervals, and (3). alternating periods of higher and lower inter-eye-blink intervals. CONCLUSIONS: Reduction of the SEBR during VDT use is primarily determined by marked visual attention, resulting in an exacerbation of dry eye symptoms in predisposed humans. High interindividual variability and distinct patterns of eye blinking may be key factors in further clarification of VDT-eye interactions and develop individually designed solutions to prevent desiccation during VDT use.

Adolescent↗

Evaluation of a head-mounted display (HMD) in the performance of a simulated laparoscopic task.

BACKGROUND: Head-mounted display (HM) units are used in various industries, but they have been tried only recently in surgery. In this study, we evaluated whether a commercially available HMD would improve or impede a laparoscopic task-in this case, suturing. METHODS: Six participants performed a total of 120 laparoscopic suture knots in an experimental model. The Olympus FMD011 model with a two-dimensional image was used. The order of each task with or without the head display unit was random. The time to complete each knot was recorded, and the results were analyzed. RESULTS: The display unit prolonged the suturing times of the subjects by 10% (p < 0.04). CONCLUSIONS: In this experimental model, the HMD we utilized did not appear to improve laparoscopic suturing. More developments, such as improved depth perception and better resolution, may increase its usefulness for laparoscopic tasks.

Computer Simulation↗

The effects of computer interface design on human postural dynamics.

The main objective of this study was to examine the effects of human-computer interface design on postural dynamics, i.e., changes in working postures and postural discomfort exhibited by operators of the computer-based remote bar coding (RBC) system. In addition, the effects of different work/rest schedules on postural dynamics were evaluated. Twelve subjects participated in the laboratory experiment, which consisted of twelve scenarios utilizing two cognitive task requirement factors, i.e., (1) information presentation mode, defined through the letter image preview on the computer screen (none or one preview image); and (2) the information processing mode, defined through the specific keying method (key all characters or key 5 digits only). The third experimental factor was the work/rest schedule (50 min work/10 min break, 2 h of work/15 min break, or flexible schedule). The results showed that requirements of human-computer interface design significantly affected the operators' postural dynamics. It was concluded that not only the physical, organizational, or psychosocial work environment characteristics, but also the cognitive task characteristics are important for assessment of postural effects in the VDT work. The relationship between interface design, mental workload and postural dynamics should be carefully considered in future studies aimed at optimizing the human-computer data entry tasks.

Adult↗

Factors influencing optical 3D scanning of vinyl polysiloxane impression materials.

PURPOSE: Future growth in dental practice lies in digital imaging enhancing many chairside procedures and functions. This revolution requires the fast, accurate, and 3D digitizing of clinical records. One such clinical record is the chairside impression. This study investigated how surface angle and surface roughness affect the digitizing of vinyl polysiloxane impression materials. MATERIALS AND METHODS: Seventeen vinyl polysiloxane impression materials were digitized with a white light optical digitizing system. Each sample was digitized at 3 different angles: 0 degrees, 22.5 degrees, and 45 degrees, and 2 digitizer camera f-stops. The digitized images were rendered on a computer monitor using custom software developed under NIH/NIDCR grant DE12225. All the 3D images were rotated to the 0 degrees position, cropped using Corel Photo-Paint 8 (Corel Corp, Ottawa, Ontario, Canada), then saved in the TIFF file format. The impression material area that was successfully digitized was calculated as a percentage of the total sample area, using Optimas 5.22 image processing software (Media Cybernetics, LP, Silver Spring, MD). The dependent variable was a Performance Value calculated for each material by averaging the percentage of area that digitized over the 3 angles. New samples with smooth and rough surfaces were made using the 7 impression materials with the largest Performance Values. These samples were tested as before, but with the additional angle of 60 degrees. Silky-Rock die stone (Whip Mix Corp, Louisville, KY) was used as a control. RESULTS: The Performance Values for the 17 impression materials ranged from 0% to 100%. The Performance Values for the 7 best materials were equivalent to the control at f/11 out to a surface angle of 45 degrees; however, only Examix impression material (GC America Inc, Alsip, IL) was equivalent to the control at f/11/\16. At the 60 degrees surface angle with f/11/\16, the Performance Values were 0% for all the impression materials, whereas that for the control was 90%. The difference in the Performance Values for the smooth and rough surface textures was 7%, which was not significant. CONCLUSIONS: The digitizing performance of vinyl polysiloxane impression materials is highly material and surface angle-dependent and is significantly lower than the die stone control when angles to 60 degrees are included. It is affected to a lesser extent by surface texture.

Analysis of Variance↗

The effect of typing posture on wrist extensor muscle loading.

High static loading of the forearm extensor musculature has been observed during keying tasks. To reduce the level of loading, one must first understand the contributing factors. A simulation of the human finger was used to determine muscle force contributions during a static index finger key press at several wrist postures. The planar model included active and passive muscle forces of the intrinsic and extrinsic finger muscles. The model was expanded to include the passive forces from the other fingers as well as the weight of the hand to determine the exertion required of the wrist extensor muscles to maintain the given wrist and finger postures. Model results indicated that greater than 25% of maximal exertion is required of the wrist extensors when the wrist is extended to 30. The increased moment contribution from passive forces of the extrinsic finger flexor muscles was responsible for the majority of the increased wrist extensor contribution as the wrist was extended. These findings are in relative agreement with previous electromyographic studies and may indicate a mechanism for forearm extensor pain in office workers. Potential applications of this research include ergonomic modeling of the upper limb to determine internal loads that may lead to work-related disorders.

Biomechanical Phenomena↗

A mechanism for stop codon recognition by the ribosome: a bioinformatic approach.

Protein synthesis in ribosomes requires two kinds of tRNAs: initiation and elongation. The former initiates the process (formylmethionine tRNA in prokaryotes and special methionine tRNA in eukaryotes). The latter participates in the synthesis proper, recognizing the sense codons. Synthesis is also assisted by special proteins: initiation, elongation, and termination factors. The termination factors are necessary to recognize stop codons (UAG, UGA, and UAA) and to release the complete protein chain from the elongation tRNA preceding a stop codon. No termination tRNA capable of recognizing stop codons by their anticodons is known. The termination factors are thought to do this. In the large ribosomal RNA, we found two sites that, like tRNAs, contain the anticodon hairpin but with triplets complementary to stop codons. One site is hairpin 69 from domain IV; the other site is hairpin 89, domain V. By analogy, we call them termination tRNAs: Ter-tRNA1 and Ter-tRNA2, respectively, even though they transport no amino acids, and suggest that they directly pair to stop codons. The termination factors only aid in this recognition, making it specific and reliable. A strong argument in favor of our hypothesis comes from vertebrate mitochondria. They are known to acquire two new stop codons, AGA and AGG. In the standard code, these are two out of six arginine codons. We revealed that the corresponding anticodons, UCU and CCU, have evolved in Ter-tRNA1 of these mitochondria.

Base Sequence↗

Office equipment and supplies: a modern occupational health concern?

The Helsinki Office Environment Study, a population-based cross-sectional study was carried out in Finland in 1991 among 2,678 workers in 41 randomly selected office buildings. The aim was to evaluate the relations between work with office equipment and supplies and the occurrence of eye, nasopharyngeal, skin, and general symptoms (often denoted as sick building syndrome (SBS)), chronic respiratory symptoms, and respiratory infections. Work with self-copying paper was significantly related to weekly work-related eye, nasopharyngeal, and skin symptoms, headache and lethargy, as well as to the occurrence of wheezing, cough, mucus production, sinusitis, and acute bronchitis. Photocopying was related to nasal irritation, and video display terminal work to eye symptoms, headache, and lethargy.

Acute Disease↗

Ergonomics in the laboratory environment.

The focus of this report is how ergonomics--the art of making equipment fit the user--is applied to video display terminal (VDT) use in order to improve productivity. It is recommended that VDT operators be made more comfortable by using ergonomic chairs and tables. The placement of computer screens and keyboards at the workstations should be tailored to the body and its natural motion in order to decrease physical stress.

Attitude of Health Personnel↗

An evaluation of ten digital image review workstations.

A suite of performance tests are defined and performed on a total of 10 primary diagnostic image review workstations. System architectures, user interface, image manipulation tools, and data retrieval rates are discussed and analyzed. Performance timings are normalized to MB/sec to remove image file size dependencies from the data analysis. Although it is likely that some performance and capacity data may be dated as this article goes to press, it is hoped that the test definitions, methodology, and baseline data will aid those contemplating equipment purchases to make a more informed choice.

Computer Terminals↗

Influence of screen and copy holder positions on head posture, muscle activity and user judgement.

A study was conducted on eight subjects, in order to investigate the influence of head posture with regards to the screen and copy holder position, the activity of cervical muscles and the subjective judgement given by the subjects. A total of eleven different positions (exercises) of screen and copy holder were investigated. Four different screen positions were examined in the upright (middle) sitting posture and three different screen positions were investigated in the backward sitting posture. In addition, four different positions of the copy holder were examined in the upright sitting posture. Head posture and muscle activity were continuously measured in each exercise for a duration of 5 min. At the end of each exercise, the subjects were asked how they judged the position of the screen and/or the copy holder in comparison with other positions. The results show that preference is to be given to a screen position in which the vision axis is horizontal or inclined slightly downwards. The copy holder should be arranged at one side of the screen.

Adult↗

[EEG-based communication--a new concept for rehabilitative support in patients with severe motor impairment].

This paper describes a paralyzed patient diagnosed with severe infantile cerebral palsy, trained over a period of several months to use an EEG-based brain-computer interface (BCI) for verbal communication. The patient learned to "produce" two distinct EEG patterns by mental imagery and to use this skill for BCI-controlled spelling. The EEG feedback training was conducted at a clinic for Assisted Communications, supervised from a distant laboratory with the help of a telemonitoring system. As a function of training sessions significant learning progress was found, resulting in an average accuracy level of 70% correct responses for letter selection. At present, "copy spelling" can be performed with a rate of approximately one letter per minute. The proposed communication device, the "Virtual Keyboard", may improve actual levels of communication ability in completely paralyzed patients. "Telemonitoring-assisted" training facilitates clinical application in a larger number of patients.

Action Potentials↗

Effects of Ergorest arm supports on muscle strain and wrist positions during the use of the mouse and keyboard in work with visual display units: a work site intervention.

The effects of Ergorest arm supports on wrist angles and musculoskeletal strain in the neck-shoulder-arm region and electrical activity in the shoulder and arm muscles were studied during typing or the use of the mouse in work with a visual display unit (VDU). Twenty-one women were randomized into 3 groups (1 arm support, 2 arm supports, and control). Measurements were carried out before and after the 6-week intervention. The wrist extension of the mouse hand, the muscle activity of the trapezius muscle, and the subjective discomfort ratings indicated that 2 arm supports were better than 1 in work with a mouse. The Ergorest arm support alleviates muscle and joint strain in VDU work when used for both arms.

Adult↗