SEARCH · PubMed Health

Results for “LEATHER”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 379 records · Page 21Linked to original sources

PubMed1998

Occupational urothelial tumours: a regional case-control study.

OBJECTIVE: To investigate the role of occupational exposures in the risk of developing urothelial cancer. MATERIALS AND METHODS: Occupational histories, obtained using a self-administered questionnaire, for 803 patients with urothelial cancer (first diagnosed 1991-93) were compared with similar information for 2135 matched controls. Relative risks (RRs) were estimated using conditional logistic regression. Comparisons were also made with historical regional employment information available from the 1971 census. RESULTS: There were many statistically significant positive associations for urothelial cancer risks and ever being employed in specified occupations (with or without statistical adjustment for smoking status in 1991). Smoking-adjusted RRs of > 2.0 were obtained for seven occupations; manufacture of fire lighters/ patent fuels (RR 4.30, 95% confidence interval 0.78-23.79), rodent extermination (3.71, 1.20-11.48), manufacture of dyestuffs (2.61, 0.98-7.00), leather work (2.51, 1.44-4.35), cable manufacturing industry (2.46, 1.20-5.04), textile printing and dyeing (2.32, 0.98-5.45), and sewage works (2.19, 1.16-4.11). Analyses of the occupations followed in 1971 (thus allowing for 20-year latency) indicated an elevated RR for workers in the plastics industry (5.22, 1.57-17.36). CONCLUSIONS: The historical legacy of exposure to aromatic amines in the rubber, cable-making, dyestuffs and other industries remains. An important proportion of patients presenting with urothelial tumours are likely to have had occupational exposure to urothelial carcinogens. A review of occupational exposures in the contemporaneous plastic, textile and leather industries is warranted.

Adult↗

PubMedDate not supplied

Durably controlling bovine hypodermosis.

Cattle hypodermosis, due to insect larvae, is widely spread over the northern hemisphere. Very efficient insecticides are available and their use in most countries are done on an individual level but never cover the whole cattle population of a country. Untreated animals remain the reservoir of the disease and annually re-infest the cattle population. The economic effects of this disease on animal production (meat, milk and the leather industry) but also on the general cattle health status, have led many European countries to launch organised control programs. The first example of definitive hypodermosis control goes back one hundred years ago when Danish farmers eradicated hypodermosis from the Danish islands by manual elimination of the warbles. Since then, more and more European countries have considered the feasibility and economic returns of such programs. The various factors which foster these programs are related to (i) biological factors, (parasite cattle specificity, synchronous biological cycles of both species of insects involved), (ii) the development of more and more efficient insecticides used only once a year by systemic application, with high efficiency at very low dosages against the first larval stage of Hypoderma spp., (iii) the development of acute techniques of detection of the disease for the monitoring of hypodermosis free countries and (iv) the durable successful results obtained in more and more European countries. Although the programs were imposed by different partners of the livestock channel production (farmers, dairy industry, leather industry) and have been engaged within the last 50 years in many European countries (Denmark, The Netherlands, Ireland, the United Kingdom, the Czech Republic, Germany, France and Switzerland) common features have emerged among these different eradication programs. They all need a preliminary statement of the economic impact of this pest and the farmers' awareness of the economic returns of such programs. The programs' efficacy depends: (i) on a good knowledge ofthe epidemiology of the parasites, (ii) on the simultaneous implementation of the control program on the whole national cattle population whatever the structure monitoring the treatments (veterinary services, farmers association), (iii) on a national Warble fly legislation making the treatments compulsory and (iv) on an acute epidemiological survey as soon as the status of a hypodermosis free country is reached and the treatments are suspended. The sanitary and financial returns of such programs are a benefit to all the partners of livestock production, to the quality of the environment and to the consumers.

Animals↗

PubMed2003

Current internal exposure to pesticides in children and adolescents in Germany: blood plasma levels of pentachlorophenol (PCP), lindane (gamma-HCH), and dichloro(diphenyl)ethylene (DDE), a biostable metabolite of dichloro(diphenyl)trichloroethane (DDT).

Pesticides are widely used throughout the world in agriculture to protect crops, and in public health to control diseases transmitted by animal vectors or intermediate hosts. After the prohibition of organochlorines such as DDT internal exposure of the general population to the organochlorines has been reduced markedly. Herein, current internal exposure of children and adolescents in an urban area in Germany to PCP, lindane, and DDT/E is reported. One hundred and thirty children and adolescents took part in this voluntary investigation. All of them stated they had never used pesticides in their homes or for medical reasons. Blood plasma was analysed for pentachlorophenol (PCP), lindane (gamma-HCH), and dichloro(diphenyl)ethylene (DDE), a biostable metabolite of dichloro(diphenyl)trichloroethane (DDT), using gas chromatography/electron capture detection according to well established methods approved by the Deutsche Forschungsgemeinschaft. Median (and 95th percentiles) in the age groups < 6, 6- < 12, and 12- < 18 years of age were (microgram/l): DDE: 0.75 (4.45), 0.95 (5.04), 0.89 (8.77); DDT: < 0.1 (0.22), < 0.1 (0.25), < 0.1 (0.30); PCP: 2.48 (17.32), 2.69 (5.85), 2.08 (8.04); lindane: < 0.1 (0.12, < 0.1 (0.08), < 0.1 (0.09). High levels of internal exposure to DDT in two girls were probably obtained during a holiday stay in India; high PCP-levels in two other girls were caused by a leather jacket impregnated with PCP, and a holiday abroad, respectively. Current background levels of internal exposure to organochlorine insecticides in children and adolescents in Germany are quantified. Exposure to these substances in the general population is thought to occur mainly via residues in food, which are low in general, today. In special cases, however, individual exposures may be dominated by other sources, i.e. impregnated leather clothes.

Adolescent↗

PubMedDate not supplied

Occupational asthma in the community: risk factors in a western Mediterranean population.

Risk factors and prevalence of occupational asthma in the general population were examined in a cross-sectional community study conducted in north Barcelona. A self-administered questionnaire that contained questions about bronchial asthma and occupation was mailed to a random sample of 4000 adults who lived in north Barcelona; the response rate was 31.0%. Investigators made phone calls to nonresponders to determine response bias. Risk factors for occupational asthma were assessed with logistic regression. Investigators, who sought a definite diagnosis of occupational asthma, offered a chest examination to all subjects who reported asthma in life and who experienced clinically relevant occupational exposures. The examination included skin tests to common allergens, forced spirometry with reversibility test, and peak expiratory flow rate at and away from work. Cumulative prevalences obtained from responders were good estimates for the general population: asthma in life, 9.0%; clinically relevant occupational exposure, 28.9%; and respiratory symptoms at work, 18.3%. Adjustments were made for age, sex, and smoking habits, and relevant exposure caused an increase in asthma risk (odds ratio [OR] = 1.9; 95% confidence interval [95% CI] = 1.1, 3.2); however, when investigators introduced specific occupations in the model as independent variables, only occupational exposure to leather (OR = 12.8 [95% CI = 4.4, 37.4]), animals (OR = 10.3 [95% CI = 1.6, 65.2]), dyes (OR = 5.6 [95% CI = 2.1, 15.3]), and flour (OR = 4.6 [CI = 1.3, 15.7]) persisted as significant risk factors. A 1.7/1000 minimum prevalence of occupational asthma for the north Barcelona population was estimated from chest examination results. Occupational risk for asthma appeared to be associated with exposure to leather, animals, dyes, or flour in the north Barcelona area.

Adult↗

PubMed2002

Reducing environmental emissions in tanneries.

Tanning, in particular chrome leather production, is still characterised by an inefficient use of raw material and the production of highly polluted wastewater and solid wastes. A part of the emissions can be prevented by introducing clean tanning technologies, the remaining emissions can be treated. Clean production technologies and waste (water) treatment technologies should have a designed complimentarity. Anaerobic wastewater treatment with recovery of sulfides, sulfur and energy (biogas) is a cornerstone in such integral clean chrome leather technology.

Animals↗

PubMed2005

Paternal effects on the defensive behavior of honeybees.

The defensive behavior of 52 hybrid honeybee (Apis mellifera L.) colonies from four sets of crosses was studied and compared with that of European and Africanized bee colonies. Colonies containing F(1) hybrid workers were obtained through reciprocal crosses between European and Africanized bees. The total number of stings deposited by workers in a moving leather patch in 1 min was recorded. In each of the four sets of crosses, bees from hybrid colonies of Africanized paternity left more stings in leather patches than bees from hybrid colonies of European paternity. Results strongly suggest paternal effects of African origin increasing the defensive behavior of hybrid colonies. Although some degree of dominance was observed for high-defensive behavior in one of the four sets of crosses involving European paternity, most of the dominance effects reported in the literature appear to be the result of paternal effects. Several hypotheses to explain this phenomenon, as well as the implications of these effects on the fitness and breeding of honeybees are discussed.

Aggression↗

PubMed1999

Small-scale field trial of a sensing device for detecting peridomestic populations of Triatoma infestans (Hemiptera: Reduviidae) in northwestern Argentina.

Two prototypes of sensing devices for detecting peridomestic populations of Triatoma infestans Klug were tested in paired trials with bamboo canes in Amamá and nearby rural villages under triatomine surveillance. In infested peridomestic structures housing domestic animals, 1-2 pairs of numbered devices were placed per test site, left for 3-9 nights, and inspected for evidence of infestation. Prototype A was a black plastic cylinder 19 cm high and 10 cm diameter, with a screw cap on the top, 2 openings in the bottom, and a removable central structure made of resistant plastic coated with leather. Prototype B had square leather pieces rolled into cylinders instead of the central structure. Prototype A was significantly more sensitive than the bamboo cane with pleated paper inside in 13 test sites in which 20 pairs were tried. In a smaller series involving 7 pairs, prototype B also detected infestations more frequently than the cane. Triatomine feces were the signs most frequently recorded by both prototypes, whereas the bamboo canes recorded no feces. Ten T. infestans and 1 Triatoma guasayana Wygodzinsky & Avalos were collected from the prototypes placed on the ground or walls, not beneath the thatched roofs of the animal shelters, whereas only 3 T. infestans were collected from the canes. This study describes an effective sensing device for detecting T. infestans populations in outdoor animal shelters and provides quantitative field data on its performance.

Animals↗

PubMed1996

Occupation and risk of germ cell testicular cancer by histologic type in Ontario.

Incidence of both major histologic subgroups of germ cell testicular cancer, seminoma and nonseminoma, is increasing, but the etiology is largely unknown. Occupational clusters have been observed. In a case-control study in Ontario with 495 incident cases and 974 population control subjects, jobs and industries were coded and analyzed. There is little evidence of occupational risk for all cases or for seminoma. Significantly increased risk of nonseminoma was associated with: miners (odds ratio [OR] = 12.39; 95% confidence interval [CI], 2.22 to 69.27), food and beverage processors (OR = 3.20; 95% CI, 1.39 to 7.35), utilities employees (OR = 3.15; 95% CI, 1.15 to 8.61), and other service workers (OR = 1.05; 95% CI, 1.05 to 4.56). Leather-industry employees had elevated risk of nonseminoma (OR = 4.60; 95% CI, 0.75 to 28.28) consistent with a leather tannery cluster. Increased risk of nonseminoma among some workers can be explained if an additional event is required for converting seminoma to nonseminoma.

Adolescent↗

PubMed2000

Occupation and prostate cancer risk in Sweden.

To provide new leads regarding occupational prostate cancer risk factors, we linked 36,269 prostate cancer cases reported to the Swedish National Cancer Registry during 1961 to 1979 with employment information from the 1960 National Census. Standardized incidence ratios for prostate cancer, within major (1-digit), general (2-digit), and specific (3-digit) industries and occupations, were calculated. Significant excess risks were seen for agriculture-related industries, soap and perfume manufacture, and leather processing industries. Significantly elevated standardized incidence ratios were also seen for the following occupations: farmers, leather workers, and white-collar occupations. Our results suggest that farmers; certain occupations and industries with exposures to cadmium, herbicides, and fertilizers; and men with low occupational physical activity levels have elevated prostate cancer risks. Further research is needed to confirm these findings and identify specific exposures related to excess risk in these occupations and industries.

Agricultural Workers' Diseases↗

PubMed1999

Managing alcohol withdrawal in the acutely ill hospitalized adult.

Managing individuals with acute illness who are at high risk for alcohol withdrawal presents multiple challenges to the treatment teams caring for them. Following realization that management of this group was often characterized by severe withdrawal symptoms (delirium tremens, seizures and the need for leather restraints), a Task Force developed protocols to guide care. Its principal goal was to avoid cardiorespiratory and neurologic morbidities associated with severe withdrawal. The first 441 episodes of care treated after protocol implementation are described in this report. There were no instances of oversedation requiring pharmacological reversal or intubation, few individuals suffered seizures outside of the emergency department and the use of leather restraints declined dramatically. Outstanding issues arising from analysis include the necessity of subjecting the symptom severity instrument to rigorous psychometric study and reconsideration of the appropriateness of a symptom-triggered approach in treating this population. Our experience suggests that use of a nonprescriptive approach by educated and motivated nursing and medical staffs can reduce serious morbidity in this at-risk population.

Acute Disease↗

PubMed2006

Cr(III) reactivity and foot dermatitis in Cr(VI) positive patients.

Chromium allergy has become synonymous with Cr(VI) allergy. However, real exposure to chromium from leather products may include both Cr(III) and Cr(VI). In this study, we investigate the reactivity to both Cr(VI) and Cr(III) in consecutive patients to analyse the relation between foot eczema/leather exposure and reactivity to Cr(III). From March 2002 to December 2004, 2211 consecutive patients with suspected allergic contact dermatitis were patch tested with 0.5% potassium dichromate (Cr(VI)) and 13% chromium trichloride (Cr(III)). A total of 71 (3.2%) patients had a positive reaction to Cr(VI), of which 31 also had a positive Cr(III) reaction. No Cr(VI) negative patients had a positive reaction to Cr(III). An increased risk of foot dermatitis was found in Cr(VI) positive patients with a concomitant positive or doubtful reaction to Cr(III) compared with Cr(VI) positive patients with no reactions to Cr(III). The increased risk was not due to a higher degree of sensitivity to Cr(VI). Leather was reported most frequently as the suspected cause of chromium dermatitis (54%). However, Cr(VI) allergics having foot eczema and positive or doubtful Cr(III) reactions often had positive reactions to other shoe allergens. Thus, Cr(III) allergy is part of a multiple shoe allergy pattern.

Allergens↗

PubMed1984

A new spinal brace for use in Duchenne muscular dystrophy.

Nine boys with Duchenne muscular dystrophy, chairbound but without scoliosis, were fitted with a recently developed brace of metal and moulded medium-density polyethylene, the modified Calot brace. Each was also fitted with a wrap-around, moulded leather jacket. Each brace held the relaxed lumbar spine in an angle of lordosis similar to that achieved by a brief active effort to sit erect without a brace. Over-all, they proved equally acceptable to patients and carers. The modified Calot brace caused substantially less restriction of pulmonary function and so may be preferable to the moulded leather jacket.

Braces↗

PubMed2007

Screening and mutagenesis of a novel Bacillus pumilus strain producing alkaline protease for dehairing.

AIMS: To characterize and optimize a novel Bacillus pumilus strain isolated from biological waste which produces protease with excellent dehairing effect. This newly isolated strain could be utilized in the industrial leather dehairing process. METHODS AND RESULTS: Bacterial strains secreting proteases were screened from biological wastes. Positive clones were further characterized by analysing their efficacy in dehairing and effects on collagen integrity. Among 171 colonies tested, a strain BA06, identified as B. pumilus, was picked owing to its efficient dehairing capabilities with minimal impact on collagen. By combined mutagenesis using UV, N-methyl-N'-nitro-N-nitrosdguanidine and Co(60)-gamma-rays, this strain was further improved with regard to its alkaline protease production. The alkaline protease activity of the mutant strain SCU11was greatly improved up to 6000 U ml(-1), in comparison with its parent strain BA06 of 1200 U ml(-1). CONCLUSIONS: By using screening and mutagenesis methods, we have successfully created a B. pumilus strain that can produce high levels of alkaline proteases that are able to efficiently remove hair from skin with minimal damage on the collagen. SIGNIFICANCE AND IMPACT OF THE STUDY: This strain could be used in commercial alkaline protease production for leather dehairing.

Animals↗

PubMed1985

Contact dermatitis in Nigeria.

Nickel is the most important sensitizer in Lagos, with an incidence of 12.3% of 453 patients tested. There was no sex difference, as the wearing of necklaces and bracelets was equally fashionable among both sexes. Housewife eczema is not common, probably because of hardening. Dermatitis from additives in the processing of leather and rubber footwear was the next most common. Chromate sensitivity comes usually from leather or cement. Cultural and climatic factors are mainly responsible for differences in the incidence of contact dermatitis found in Lagos from other countries.

Adolescent↗

PubMed1996

Occupational dermatitis in shoemakers.

In an epidemiological study of occupational dermatitis in 5 different shoe factories, 246 workers were interviewed, examined and patch tested using standard and occupational patch test series. The prevalence of occupational contact dermatitis was 14.6% (36/246): 8.1% (20/246) irritant contact dermatitis (OICD) and 6.5% (16/246) allergic contact dermatitis (OACD). Among the latter, the most common occupational allergens were p-tert-butylphenol-formaldehyde resin and mercaptobenzothiazole. 6% (15/246) presented with hyperkeratosis of the fingertips, while 3.2% (8/246) reported pruritus sine materia (PSM) present only during working hours. 2 workers presented with vitiligo-like leukodermic patches on the backs of their hands and on their forearms. Some jobs were more frequently associated with skin complaints. In the assembly department, OACD was most frequent (11.4%), attributed to contact with adhesives and, to a lesser degree, with rubber and leather. OICD caused by contact with the solvents contained in adhesives and varnishes was most frequent in the assembly and trimming departments (17.1% and 15.6%, respectively). PSM, probably caused by the dust present in the working environment was reported by 33.3% of the workers in the sole-cutting and scraping departments. Hyperkeratosis of the fingertips, as a reaction to the continuous trauma of leather on the skin, was observed most frequently (41.6%) in the sole-cutting department.

Adhesives↗

PubMed1990

How do dogs determine the direction of tracks?

Two professional tracking dogs were brought in at right angles to 50-m-long tracks to try to identify the clues that the dogs used to determine the direction of the tracks. When the dogs were tested on tracks laid by a walking man, they took the direction that the track-maker had moved significantly more often than predicted by random choice regardless of whether the person had moved forwards or backwards. When tested on tracks laid by bicycling on grass or asphalt, the choice of direction was not significantly different from random, even though the dogs were always rewarded when making correct choices. When four leather strips were tied to the back tyre of the bicycle before laying the track, the one dog tested took the correct direction significantly more often than predicted by random choice. When the leather strips were smeared with sausage before laying the tracks, the dog took the wrong direction more often than predicted by random choice. However, when rewarded for making correct choices, the dog learned to choose the direction in which the bicycle had actually moved. We suggest that our dogs determined the direction of tracks by comparing the scents of consecutive prints and following the prints in the direction of increasing intensity.

Animals↗

PubMed1998

7500 years of prehistoric footwear from arnold research cave, missouri

Accelerator mass spectrometer dating of an assemblage of fibrous and leather footwear from Arnold Research Cave in central Missouri documents a long sequence of shoe construction by prehistoric Midwestern peoples, beginning perhaps as early as 8300 calendar years before the present (cal years B.P.). An earlier fibrous sandal form dates from 8325 to 7675 cal years B.P., and later fibrous or leather slip-ons span the period from 5575 to 1070 cal years B.P. The assemblage adds to a growing picture of the highly varied nature of prehistoric footwear production in the United States throughout the Holocene.

Journal Article↗

PubMed1970

Potentially infectious agents associated with shearling bedpads. I. Effect of laundering with detergent-disinfectant combinations on polio and vaccinia viruses.

Glutaraldehyde-tanned woolskin pads which are used for the prevention of decubitus ulcers in bed patients were experimentally contaminated with polio or vaccinia viruses. Two methods of exposure, direct contact and aerosol, were used in separate experiments. Attempts were made to remove or inactivate these virus contaminants by laundering the woolskins in a quaternary ammonium disinfectant, a phenolic disinfectant, or alkalinized glutaraldehyde, in combination with an anionic detergent or a nonionic detergent. The effect of a commercial detergent-sanitizer was also studied. The virus titers were significantly reduced in all experiments, but only laundering in glutaraldehyde in combination with either detergent lowered the vaccinia virus titers to below detectable limits. High concentrations of glutaraldehyde altered the texture of the wool and leather apparently by precipitating a component of the detergent onto the fibers. In all the poliovirus experiments, the virus was still detectable on either or both the wool and the leather of the pads after laundering. The rinse water from each experiment was tested for the presence of virus. No vaccinia virus was recovered, but poliovirus was demonstrated in titers up to 10(3) cell culture 50% infectious doses.

Animals↗