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PubMed1978

Milk drinking by the elderly of three races.

The three objectives of this study were to determine: (a) If milk was acceptable for multi-racial groups of elderly people, some of whom had previously been described as lactose intolerant, (b) the frequency of milk rejection attributed to symptoms of lactose intolerance, and (c) the importance of offering different types of milk. The study was carried out on 347 elderly citizens participating in the Title VII Nutrition Program for the Elderly in Harris County, Texas. Eighty-five per cent of the Mexican-Americans, 93.5 per cent of the blacks, and 94 per cent of the Anglos surveyed reported drinking the milk served with their meal. Only 6.6 per cent of the Mexican-Americans, 1.4 per cent of the blacks, and 2.5 per cent of the Anglos did not consume the milk because of symptoms that might be related to low levels of intestinal lactase. It was concluded that milk could and should be served to multi-racial groups of elderly people. Offering a choice of milk type appeared to be important for acceptance. Twenty-two per cent of the blacks, 4 per cent of the Mexican-Americans, and 16 per cent of the Anglos always preferred buttermilk.

Black or African American↗
PubMed1983

Lactose intolerance in adults with chronic unspecific abdominal complaints.

77 hospitalized patients with chronic unspecific abdominal complaints, in whom any other organic disease had been previously excluded, were investigated for lactose malabsorption; they were subdivided into two groups: 46 patients complaining primarily of colicky abdominal pain and/or intermittent diarrhoea (group 1) and 31 patients presenting with dyspepsia as the predominant symptom (group 2). To establish the exact prevalence of isolated lactase deficiency in the healthy adult population served by our hospital, 40 Italian adult healthy subjects were also studied. The prevalence of lactose malabsorption was significantly higher (p less than 0.005) in patients of the 1st group than in patients of the 2nd group, and in the healthy adult population seen at our hospital (74% vs 35.5% and 37.5%, respectively). Furthermore a high prevalence of lactose intolerance, determined by means of a three-week diet trial (lactose free-diet versus normal diet), was documented among lactose malabsorbers of the 1st group. We concluded therefore that lactose intolerance is a factor in some Italian adult patients who suffer from long-standing aspecific abdominal discomfort, and it should be always considered in these patients, especially when colicky abdominal pain and diarrhoea are present, before the diagnosis of irritable bowel syndrome is made.

Abdomen↗
PubMed1980

Intestinal disaccharidase activities and activity ratios in a group of 60 adult German subjects.

Lactase, maltase and sucrase activities were determined in samples of jejunal mucosa obtained by suction biopsy from 60 healthy adult German males. Primary adult hypolactasia ("lactase deficiency") was found in 8 subjects (13%). Maltase:lactase and sucrase:lactase activity ratios were significantly higher in post-weaning hypolactasia than in adult lactase persistence. Sources of variation in disaccharidase activities measured in biopsy tissue homogenates are discussed.

Adult↗
PubMed1981

[Effect of cimetidine on lactose activity in patients with duodenal ulcer].

A significant decrease of the lactose levels (p less than .001) and of the glucose peaks after an overcharge of lactose (p less than .01) were found in 10 patients with duodenal ulcer after a treatment of 35 days with 1,2 daily grams of Cimetidine, when they were compared with a group treated with placebos. Also, a significant increase of the diarrhea associated with the overcharge of lactose (p less than .005) was obtained. The relation between the increase of the pH and the decrease of the lactose values was significant (r = 0,44 - p less than .01).

Cimetidine↗