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PubMed1971

Meningococcal infections. 5. Duration of polysaccharide-vaccine-induced antibody.

Serum antibodies induced in 12 volunteer subjects by injection of group A and group C meningococcal polysaccharide vaccines were found to persist for periods exceeding 14 months. Antibody response was measured by indirect haemagglutination and fluorescent antibody assays. Peak titres were reached in 2-8 weeks.

Antibody Formation↗
PubMed1980

Meningococcal infections in a district hospital. Some clinical observations and therapeutic experiences during an epidemic in North Norway.

From 1974 to 1980, 70 patients with meningococcal disease were treated in the Harstad district hospital. Six patients died (8.6%). The prognostic score system of Niklasson gave an average of 2.31 for unfavourable factors which is high as compared to other studies. The percentage of high risk patients (score higher than three) was 24.3. Fifty-four patients were treated with benzylpenicillin as the sole antibacterial agent. The standard duration of therapy was five days, which is shorter than commonly recommended. Meningococci of serogroup B were most often isolated; nearly all of them sulphonamide resistant.

Adolescent↗