[Granular cell myoblastoma of the pharynx].
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Abrikossoff's tumor is a benign lesion affecting the oropharynx in more than half the cases. Five cases are reported and symptoms and signs reviewed. Treatment was by wide excision, although a less extensive operation is possible to avoid major damage to surrounding structures. This attitude can be adapted because the course of the affection is by slow progression, with the possibility of no further growth, and the fact that surgery can be repeated.
Histological and ultrastructural description of a granular-cell tumor of the rectum in a male of 33 is presented.
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An 18-year-old woman had a 3-month history of increasing proptosis and visual loss secondary to an inferior orbital mass. Surgical exploration revealed an encapsulated mass in the orbit. After this mass was excised good vision was restored. The diagnosis of granular cell tumor was made as a result of various microscopic studies. The location of the tumor within the orbit is unusual and its histologic origin is uncertain. Immunohistochemistry by peroxidase-antiperoxidase method revealed that this tumor had S-100-protein-positive cells and negative results for lysozyme and alpha-1-antitrypsin. This fact suggests that the origin of the granular cell tumor may be due to the Schwann cell.
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