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At least 379 records · Page 21Linked to original sources
PubMed2004

Lipoma-like tumor mass probably arising in the retroperitoneal heterotopic pancreas: a previously undescribed lesion.

Heterotopic pancreatic tissue is found in several locations of the body. However, to the best of our knowledge, there have been no reports on heterotopic pancreas in the retroperitoneum. A case of retroperitoneal lipoma-like large tumor mass probably arising in the heterotopic pancreas is reported. A 45-year-old Japanese woman was admitted to hospital because of back pain. Imaging modalities showed an abnormal mass in the retroperitoneum separate from the surrounding organs, including the pancreas and kidney. Histologically, the mass consisted of mature adipose tissue and scattered ductal and acinar elements. Although there was no islet tissue in this fatty mass, the epithelial elements suggested heterotopic pancreatic tissue in origin. The present case is very unusual; however, heterotopic pancreas should be considered in the differential diagnosis of retroperitoneal tumors.

Biomarkers, Tumor↗
PubMed2006

Long-term survival under maintenance gemcitabine chemotherapy for metastatic transitional cell carcinoma.

We report a case of a 74-year-old patient who received 41 courses of maintenance therapy with gemcitabine over a length of 28 months for metastatic transitional cell carcinoma. One year earlier the patient had received three cycles of adjuvant cisplatin-based combination chemotherapy after nephro-ureterectomy for a locally advanced urothelial cancer of the right renal pelvis. This case demonstrates a paradigm shift in the palliative treatment of advanced urothelial cancer, with the implementation of more tolerable agents such as gemcitabine. Even elderly patients with impaired renal function may benefit in terms of tumor reduction and survival from systemic chemotherapy, which may be applied over a prolonged period of time.

Aged↗
PubMed1980

Malignant fibrous histiocytoma.

Seven cases of malignant fibrous histiocytoma are reported. Two patients had tumour involving the scrotum and small-gut mesentery, which are unusual primary sites, while three others with pulmonary metastases are alive five years since the appearance of these metastases. A review of the histogenesis, biological behaviour and the treatment of these uncommon tumours suggests that the prognosis is good even in the presence of advanced local or metastatic disease. Radiotherapy controlled the primary lesion in one patient and was effective in treating pulmonary metastases in three, suggesting that these tumours do show a response to radiotherapy. The prophylactic use of radiotherapy and chemotherapy awaits further evaluation.

Aged↗
PubMed2007

Endoscopic ultrasound guided fine needle aspiration of non-pancreatic lesions: an institutional experience.

BACKGROUND: Endoscopic ultrasound guided fine needle aspiration biopsy (EUS-FNA) has proven to be an effective diagnostic modality for the detection and staging of pancreatic malignancies. In recent years EUS-FNA has also been used to diagnose lesions of non-pancreatic sites such as structures in close proximity to the gut wall within the mediastinum, abdomen, pelvis and retro-peritoneum. AIMS: To evaluate experience with EUS-FNA of non-pancreatic sites at a large university medical centre. METHODS: The study cohort included 234 patients who underwent EUS-FNA of 246 lesions in non-pancreatic sites (122 peri-pancreatic and coeliac lymph nodes; 9 peri-pancreatic masses; other sites: mediastinum 12, gastric 25, liver 27, oesophagus 17, duodenum/colon/rectum 15, retro-peritoneum 8, lung 7, miscellaneous 4). RESULTS: The cytology diagnoses were classified as non-neoplastic/reactive in 82 (33%), atypical/suspicious for malignancy in 25 (10%), malignant in 86 (35%) and non-diagnostic in 53 (22%) cases. Surgical pathology follow-up was available in 75 (31%) cases. Excluding the non-diagnostic cases there were 7 false negative and 3 false positive cases. The sensitivity, specificity and positive predictive value of EUS-FNA in the diagnosis of lesions of non-pancreatic sites was 92%, 98% and 97%, respectively. CONCLUSIONS: EUS-FNA can be effectively used as a diagnostic modality in the diagnosis of lesions from non-pancreatic sites.

Adolescent↗
PubMed1977

Ultrasonography and computed tomography in the diagnosis of homogeneous masses.

Ultrasonography can demonstrate the homogeneity, while CT can demonstrate the density of a mass lesion. If a mass appears echo-free at ultrasonography, but is denser than water at CT, a solid tumor with grossly uniform cellular structure (usually a lymphoma or sarcoma), or a hematoma or hemorrhagic cyst is likely. However, if the mass has water density at CT, a cystic lesion is confirmed. One case for each category is presented.

Adult↗
PubMed1978

CT biopsy of abdominal tumors: aids for lesion localization.

Computed tomographic guided fine needle aspiration biopsy of 25 consecutive patients with a variety of confirmed malignant abdominal and plevic neoplasms resulted in a 100% yield of positive tissue diagnosed, without significant complications. The principal advantage of CT guidance is the continuous direct observation of the needle tip position in relation to the target volume. Simultaneous insertion of 2 fine caliber biopsy needles (tandem needle maneuver) is a new technique developed for rapid, accurate needle repositioning for repeated aspiration attempts. CT guidance, multiple aspirates with the fine needle, and the tandem needle maneuver for precise localization all contribute to a high rate of tissue diagnoses. Because CT guidance permits more precise sampling of smaller, deeper tumors than other procedures, including ultrasonic biopsy transducer systems, it is preferred for percutaneous tissue sampling of abdominal neoplasms. Preliminary experience suggests that a large proportion of symptomatic abdominal malignancies which can be diagnosed by CT are amenable to successful percutaneous biopsy by this technique.

Abdominal Neoplasms↗
PubMed1979

Alteration of perirenal fat secondary to diffuse retroperitoneal infiltration.

Inflammatory effusions and diffuse neoplasia in the fatty retroperitoneal space, which can alter the perirenal fat, can be recognized radiographically because of density differences. The opacity of fluid and tumor accentuates the remaining fat which conforms to the renal contour. This perirenal fatty border appears as a lucent strip when the perirenal fat is not violated and as abnormal perirenal streakiness when the perirenal fat is infiltrated by fluid or tumor. Six cases are described.

Abscess↗
PubMed1975

Angiographic features of peripancreatic malignant lymphoma.

Angiographic features are described in 5 patients with peripancreatic lymphomas who initially presented with clinical features of primary pancreatic disease. Each patient demonstrated a large hypovascular mass with considerable displacement of pancreatic and peripancreatic arteries and associated compression of adjacent veins. Smooth arterial encasement was present in 2 cases. Signs of mass out of proportion to signs of invasion mitigated against the diagnosis of carcinoma in each case. Other differential diagnostic considerations are pancreatic pseudocyst and cystadenoma.

Aged↗
PubMed1991

Preliminary results of MR imaging with superparamagnetic iron oxide in pancreatic and retroperitoneal disorders.

The authors conducted a preliminary evaluation of the potential of superparamagnetic iron oxide as contrast material for delineation of the bowel. Ten patients with various pancreatic diseases and 18 patients with suspected retroperitoneal disease underwent T1- and T2-weighted MR imaging before and after contrast material was administered. Two radiologists reviewed randomized images and scored them for depiction of anatomic structures and abnormalities. In most patients, postcontrast T1-weighted images showed improved delineation of the retroperitoneal small bowel (duodenum), stomach, and pancreas. Postcontrast T2-weighted images showed improved delineation of retroperitoneal small bowel, para-aortic region, peripancreatic fat, and renal veins. There was no improvement in delineation of retroperitoneal diseases, except for lymphadenopathy, which was better seen on both T1- and T2-weighted postcontrast images. Preliminary results suggest that superparamagnetic iron oxide is a useful contrast agent for delineating some normal retroperitoneal structures, lymphadenopathy, and pancreatic disease and that it is less useful in evaluating other retroperitoneal masses.

Adipose Tissue↗
PubMed1993

Differential diagnosis of fat-containing lesions with abdominal and pelvic CT.

Recognition of fat within an organ or lesion on abdominal and pelvic computed tomographic scans is an important clue to guiding a differential diagnosis. A systematic approach to these lesions, including a patient's age and clinical history, along with the appearance and location of the lesion often allows a specific differential diagnosis. The anatomic sites of origin for these lesions are the gastrointestinal tract, genitourinary system, and retroperitoneum. Some of the more common entities include various forms of fatty change in the liver, fibrofatty mesenteric proliferation in Crohn disease, ovarian dermoids, and herniations of abdominal fat. In addition, pitfalls such as pathologic processes engulfing normal fat (eg, perirenal abscess) and iatrogenic incorporation of normal fat (eg, omental packing in liver lacerations) should also be included in the differential diagnosis. Familiarity with certain benign occurrences, such as focal fat in the liver adjacent to the falciform ligament and lipomatous infiltration of the ileocecal valve, obviates invasive diagnostic procedures.

Abdominal Neoplasms↗
PubMed1987

Review of iliopsoas anatomy and pathology.

The iliopsoas compartment acts as a conduit for the spread of disease within the body. Knowledge of its anatomy facilitates the early diagnosis of some potentially fatal lesions.

Abscess↗
PubMed1981

Computed tomography of abdominal fatty masses.

Computed tomographic (CT) scans of 34 cases of abdominal fatty masses were reviewed retrospectively in order to establish criteria for distinguishing benign conditions from malignant tumors. By evaluating location, attenuation, internal consistency, and margination, it is possible not only to make this distinction but frequently to suggest a specific diagnosis. Abdominal fatty masses that are sharply marginated, homogeneous, and that show CT numbers less than or equal to the patient's normal fat can be considered benign. Malignancy should be suspected when an extrarenal abdominal fatty mass displays one or more of the following characteristics: inhomogeneity, infiltration or poor margination, CT numbers greater than the patient's normal fat, or contrast enhancement. Criteria for distinguishing between angiomyolipoma and liposarcoma are also discussed.

Abdominal Neoplasms↗