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PubMedDate not supplied

Acute salpingitis and thiamphenicol: a microbiologic and therapeutic study.

Eighty-five sexually active women with clinically suspected adnexitis and illness severe enough to require hospitalization were studied. The clinical diagnosis, based on anamnestic data and physical and pelvic examination, was confirmed by laparoscopy and by cultures for aerobic and anaerobic bacteria and for Chlamydia in both cervical canal and intraperitoneal secretions. A ten-day course of thiamphenicol was begun on an empirical basis after laparoscopy. The results showed that fever, an elevated erythrocyte sedimentation rate, and leukocytosis are unreliable diagnostic parameters and that laparoscopy in conjunction with microbial cultures is the only method by which a definite etiologic diagnosis can be established. Positive results of cultures of specimens from the cervical canal are sufficient for the diagnosis of infection due to Neisseria gonorrhoeae, whereas positive culture results for specimens from the intraperitoneal cavity are necessary for the diagnosis of infection caused by Chlamydia trachomatis. Primary treatment with thiamphenicol was successful in 77 (91%) of the 85 patients. Thus, thiamphenicol proved to be effective in the treatment of acute adnexitis.

Acute Disease↗
PubMedDate not supplied

Clindamycin and ibuprofen effects on chlamydial salpingitis in mice.

To evaluate the effects of clindamycin and ibuprofen on a model of upper genital tract chlamydial infection in mice, 64 Swiss Webster white mice were inoculated in the left ovarian bursa with a mouse pneumonitis strain of Chlamydia trachomatis. Chlamydia-inoculated mice received clindamycin, ibuprofen, clindamycin and ibuprofen, or no treatment. Mice were killed at intervals, and their genital tracts were examined grossly and microscopically for evidence of infection and cultured for Chlamydia. Sixty-seven per cent of inoculated, untreated mice manifested gross evidence of inflammation compared with 22.4% of mice in any treatment group (P less than .025). C. trachomatis was isolated in 10.2% of mice treated with any drug regimen, whereas 46.7% of untreated mice were culture-positive (P less than .025). In this model, therapy with clindamycin, ibuprofen, or both drugs in combination decreased gross and histologic evidence of inflammation as well as the rate of recovery of C. trachomatis from the genital tract.

Animals↗
PubMed2001

Foreign matter salpingitis 3 years after typhlitis.

This case suggests that typhlitis may cause delayed abdominal pathology. A history of this condition should be considered in the work-up of any patient with gastrointestinal or genitourinary pathology.

Abdomen, Acute↗
PubMed1989

Asymptomatic salpingitis in intrauterine contraceptive device users.

Serial histological sections of the fallopian tubes of 50 asymptomatic subjects undergoing voluntary tubal ligation were evaluated for morphological evidence of inflammation. Twenty-five subjects had history of IUD use (the study group) and the rest 25 had never used a device (the control group). Evidence of inflammation was found in 11 out of 25 subjects in the IUD users compared to only 2 out of 25 subjects in the non-users (p less than 0.001). The relative risk was 5.5 times. Both acute and chronic inflammation of the oviducts were observed more often in the IUD users, though clinically and at surgery there was no apparent evidence of pelvic inflammatory disease.

Adult↗
PubMed1986

Tubal resection and anastomosis. II. Isthmic salpingitis.

The results of 30 consecutive operations for medial occlusion of the tube due to pathological processes other than sterilization are reported. Resection of the obstructed segments was followed by anastomosis of lateral isthmus or ampulla to the medial isthmus, the interstitial portion of the tube, or the endometrium of the lateral uterine angle, deep in the myometrium. Life table analysis of subsequent pregnancies was carried out in a manner that kept those patients with demonstrated reocclusion after anastomosis in the denominator for the duration of longest follow-up, irrespective of further operations on these patients. The cumulative probability of pregnancy was 55% at 6 months from the time of surgery and 67% at 12 and at 15 months. Empirically, average fecundability, or monthly probability of pregnancy, was 9.3%; of 25 women followed-up and not on contraception, 14 (56.0%) have conceived. Microsurgical tubal anastomosis can effectively replace uterotubal implantation for acquired organic occlusion of the medial tube or lateral uterine angle. Optimum results require precise techniques, wide excision of abnormal endosalpinx, and preoperative treatment of endometritis.

Adult↗