[AN EXPERIMENT FOR DIFFERENTIATION OF LEUKEMIC CELLS BY TREATMENT OF THE SMEAR WITH A SUSPENSION OF NEUTROPHILS].
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To evaluate oxygen transport function of Hb in lymphoid sarcomas, 15 patients aged 16-63 were examined for Hb oxygen capacity, concentrations of fetal Hb and creatinin, basic ligands H+, CO2, 2,3-diphosphoglycerate (2,3-DPG). Oxy-Hb dissociation curves were plotted. The patients' blood contained HbF in elevated quantities, whereas red cells had high creatinin. This emphasizes the role of hemolysis in genesis of anemia in lymphosarcomas. 70% of the examinees retained normal Hb affinity to oxygen in vivo, in 30% this affinity exceeded the standard. Compensatory mechanism responsible for low Hb affinity to oxygen in this disease fails. Therefore lymphosarcoma patients with anemia need early replacement hemotransfusions.
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The study group included 18 patients with isolated malignant lymphoma of the stomach (lymphosarcoma--15, reticulosarcoma--2 and Hodgkin's sarcoma--1). Correct diagnosis was made or suspected on the basis of clinical, X-ray and endoscopic data before surgery in 12 cases. Out of the 18 patients operated on, radical surgery was performed in 16 cases, and two patients died in postoperative period. Longterm results were studied in 11 cases; one of them (female) died 18 months after the operation. Four patients have survived 5 years, two--5-10 years and longer. Extirpation of the stomach has proved to be most effective in surgical treatment for isolated lymphosarcoma.