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[Development of a software for realtime display of physiological informations in human centrifuge training equipment].

OBJECTIVE: To develop a software for realtime display of physiological informations during human centrifuge training. METHOD: A software composed of CParaSetDlg, CRevMsg, CSndMsg, CWaveDsp and other classes was designed in Visual C + +6.0 environment, with object_oriented ideology. Some technical problems such as displaying the scrolled curves in realtime way, synchronous display of the waves with different sampling rates, acceleration and deceleration of the scroll were solved. RESULT: The software can display and store multiplex channels of wave signals and digital messages in realtime, synchronous way according to user's choices, with high reliability and friendly man-machine interface. CONCLUSION: This software fulfils the requirements for medical monitoring and data evaluation in human centrifuge training.

Centrifugation↗

Differences between the Cerec-3D software versions 1000 and 1500.

The Cerec-3D software was introduced officially at the IDS 2003 with the version 2.00 R1000. The decisive difference compared with the preceding software generations was that the prepared tooth and the restoration were displayed three dimensionally. Thus, the virtual changes which could be made with the aid of editing tools could also be controlled and seen immediately in 3D. The latest officially available version of the Cerec-3D software version 2.10 R1500 differs in some further developments from the first version 2.00 R1000; these are for example: --If the semiautomatic margin detector is switched off while marking the preparation margin, the alternative intensity image appears instead of the 3D display. --Designing has been decisively improved by the extension of the "Drop" tool (function of continuous application and removal of material). --Under morphologically difficult circumstances, the design proposal can be magnified/reduced in size and repositioned in all spatial directions. --The Parameter setting again permits setting an adhesive gap width specific to the dentist and unit. As an example, the version 1500 software is demonstrated on a simple clinical case in which the occlusion points were defined virtually with the aid of a functional bite registration, eliminating the need for occlusal grinding-in.

Computer-Aided Design↗

Software engineering in medical informatics: the academic hospital as learning environment.

In 2001, the revised course Software Engineering has been implemented in the Medical Informatics curriculum at the Academic Medical Center, Amsterdam. This 13 weeks, full-time course consists of three parts: internship, theory and project. All parts are provided in problem-oriented manner with special attention for relevant skills such as project management, documentation and presentation. During the internship, students observe how health care professionals at several hospital wards work and how information supply is organized. In the theory part, students study concepts and methods of software engineering by means of case descriptions and self-directed learning. During the project, they apply their acquired knowledge to an observed, clinical information problem and complete several stages of the software engineering process. Evaluation by inquiry showed that, compared to other courses, students spent more time, and distributed their time more evenly, during the whole period of the course. In conjunction with theory, a combination of internship and project in a hospital seems to provide a surplus value compared to a practical in a computer laboratory. The integration of software theory, clinical practice and problem-based approach, contributed to the enthusiastic, intensive and realistic way students learned in this important topic that might be chosen as a future profession.

Curriculum↗

Integrated software suite for magnetocardiographic data analysis--a proposal based on an interactive programming environment.

OBJECTIVES: This paper describes an integrated software suite (ISS) for the processing of magnetocardiographic (MCG) recordings obtained with super-conducting multi-channel systems having different characteristics. We aimed to develop a highly flexible suite including toolboxes for current MCG applications, organized consistently with an open architecture that allows function integrations and upgrades with minimal modifications; the suite was designed for the compliance not only of physicists and engineers but also of physicians, who have a different professional profile and are accustomed to retrieve information in different ways. METHODS: The MCG-ISS was designed to work with all common graphical user interface operative systems. MATLAB was chosen as the interactive programming environment (IPE), and the software was developed to achieve usability, interactivity, reliability, modularity, expansibility, interoperability, adaptability and graphics style tailoring. Three users, already experienced in MCG data analysis, have intensively tested MCG-ISS for six months. A great amount of MCG data on normal subjects and patients was used to assess software performances in terms of user compliance and confidence and total analysis time. RESULTS: The proposed suite is an all-in-one analysis tool that succeeded in speeding MCG data analysis up to about 55% with respect to standard reference routines; it consequently enhanced analysis performance and user compliance. CONCLUSIONS: Those results, together with the MCG-ISS advantage of being independent on the acquisition system, suggest that software suites like the proposed one could uphold a wider diffusion of MCG as a diagnostic tool in the clinical setting.

Diagnosis, Computer-Assisted↗

Comparison between 18F-FDG PET, in-line PET/CT, and software fusion for restaging of recurrent colorectal cancer.

UNLABELLED: The aim of this study was to compare PET with (18)F-FDG PET, in-line PET/CT, and software fusion of independently acquired CT and PET scans for staging of recurrent colorectal cancer (CRC). METHODS: Fifty-one patients with suspected recurrent CRC were studied with in-line PET/CT. Thirty-four of these patients underwent an additional CT scan of the chest or abdomen within 4 wk of PET/CT. Software fusion of PET and CT was performed using a fully automated, intensity-based algorithm. The accuracy of the coregistration of PET and CT scans was evaluated by measuring the distance between landmarks visible in the PET and CT images. Histologic evaluation and follow-up for 6 mo served as the gold standard for the presence or absence of recurrent CRC. RESULTS: On a patient basis, the accuracy of staging was significantly higher for in-line PET/CT than for PET (88% vs. 71%, P = 0.01). Software fusion of the independently acquired PET and CT images was unsuccessful in 8 patients (24%). In the remaining patients, the mean distance between 62 landmarks visible in PET and CT was 12.9 +/- 7.9 mm, whereas it was only 7.7 +/- 4.7 mm for in-line PET/CT (P < 0.001). CONCLUSION: In patients with suspected recurrent CRC, in-line PET/CT significantly improves staging compared with PET alone. Due to its high failure rate, software fusion of independently acquired PET and CT studies cannot be considered to represent an alternative to in-line PET/CT.

Algorithms↗

Does PET/CT render software registration obsolete?

It was the success of software-based image registration that eventually led to the introduction of hardware-based concepts for image fusion, such as combined PET/CT tomographs. A prototype PET/CT was first presented in 1998, with various commercial designs to follow since 2000. PET/ CT is used primarily as a diagnostic modality in the field of extra-cerebral oncology imaging. The major advantage of combined imaging over retrospective software registration is the nearly identical position of the patient during both complementary examination, and therefore tomograms of identical parts of the body can be provided in spatially-corresponding slices. Despite the availability of hardware combinations of complementary imaging modalities software-based image registration, however, still inherits a major role in subsequent data processing, in particular when individual imaging modalities other than combined PET/CT are being used during patient workup. Furthermore, software is likely to become an important tool for the correction of residual motion-induced mis-registration within combined PET/CT data sets, and for follow-up studies involving, for example, CT, PET, and PET/CT. Therefore, flexible algorithms that utilize non-linear interpolation schemes implemented on fast computer systems are needed, and will continue to contribute to successful image registration and fusion in clinical practice.

Brain↗

A study of clinically related open source software projects.

Open source software development has recently gained significant interest due to several successful mainstream open source projects. This methodology has been proposed as being similarly viable and beneficial in the clinical application domain as well. However, the clinical software development venue differs significantly from the mainstream software venue. Existing clinical open source projects have not been well characterized nor formally studied so the 'fit' of open source in this domain is largely unknown. In order to better understand the open source movement in the clinical application domain, we undertook a study of existing open source clinical projects. In this study we sought to characterize and classify existing clinical open source projects and to determine metrics for their viability. This study revealed several findings which we believe could guide the healthcare community in its quest for successful open source clinical software projects.

Clinical Medicine↗

sispread: A software to simulate infectious diseases spreading on contact networks.

OBJECTIVES: We present a simulation software which allows studying the dynamics of a hypothetic infectious disease within a network of connected people. The software is aimed to facilitate the discrimination of stochastic factors governing the evolution of an infection in a network. In order to do this it provides simple tools to create networks of individuals and to set the epidemiological parameters of the outbreaks. METHODS: Three popular models of infectious disease can be used (SI, SIS, SIR). The simulated networks are either the algorithm-based included ones (scale free, small-world, and random homogeneous networks), or provided by third party software. RESULTS: It allows the simulation of a single or many outbreaks over a network, or outbreaks over multiple networks (with identical properties). Standard outputs are the evolution of the prevalence of the disease, on a single outbreak basis or by averaging many outbreaks. The user can also obtain customized outputs which address in detail different possible epidemiological questions about the spread of an infectious agent in a community. CONCLUSIONS: The presented software introduces sources of stochasticity present in real epidemics by simulating outbreaks on contact networks of individuals. This approach may help to understand the paths followed by outbreaks in a given community and to design new strategies for preventing and controlling them.

Algorithms↗

Noviceware: a model for learning the software development process.

Students and nursing faculty without formal computer science training can collaborate within an independent study structure to assist the student in gaining experience with the fundamentals of software development. The systems development life cycle approach provides an essential map to structure such independent studies. This article describes the development within an academic setting of a computerized research management system. The software builds a database of research case demographic data and data from a 65-item tool used in scoring videotapes of caregiver-infant interactions. For students and faculty contemplating similar projects, recommendations about planning software development experiences and securing hardware, software, and expert resources are provided.

Algorithms↗

Record linkage strategies: Part II. Portable software and deterministic matching.

Software to perform record linkage should have several characteristics: (1) portability in being able to function with researchers' current arrangement of computer systems and languages, (2) flexibility in handling different linkage strategies, and (3) low cost in both computer time and researchers' efforts. A linkage package (LINKS) is described which satisfies these criteria; LINKS provides tools for both deterministic and probabilistic linkage as well as test modules for assessing data quality and structure. Because each linkage project is different, the modular nature of the software allows for better control of the programming process and development of unique strategies. Since the user provides the weights and decision rules, he may modify data between steps and/or develop extra steps to supplement the basic modules. In two information-rich linkage projects involving California AIDS data, LINKS identified mortality using deterministic approaches and permitted comparisons with other software and strategies. Flexible software and a deterministic approach would have eliminated the expensive key entry used to add full names and social security numbers as additional identifiers to one of the California data files.

Acquired Immunodeficiency Syndrome↗

A software system for interactive and quantitative visualization of multidimensional biomedical images.

A comprehensive software system called ANALYZE has been developed which permits detailed investigation and evaluation of 3-D biomedical images. The software can be used with any 2-D or 3-D imaging modality, including x-ray computed tomography, radionuclide emission tomography, ultrasound tomography, magnetic resonance imaging and both light and electron microscopy. The package is unique in its synergistic integration of fully interactive modules for direct display, manipulation and measurement of multidimensional image data. Several original algorithms are included which improve image display efficiency and quality. One of the most versatile and powerful algorithms is interactive volume rendering, which is optimized to be fast without compromising image quality. An important advantage of this technique is to display 3-D images directly from the original data and to provide on-the-fly combinations of selected image transformations and/or volume set operations (union, intersection, difference, etc.). The inclusion of a variety of interactive editing and quantitative mensuration tools significantly extends the usefulness of the software. Any curvilinear path or region-of-interest can be manually specified and/or automatically segmented for numerical determination and statistical analyses of distances, areas, volumes, shapes, densities and textures. ANALYZE is written entirely in "C" and runs on several standard UNIX workstations. It is being used in a variety of applications by over 40 institutions around the world, and has been licensed by Mayo to several imaging companies. The software architecture permits systematic enhancements and upgrades which has fostered development of a readily expandable package. ANALYZE comprises a powerful "visualization workshop" for rapid prototyping of specific application packages, including applications to interactive surgery simulation and radiation treatment planning. ANALYZE offers the potential to accurately and reproducibly examine, from images, the structure and function of any cell, tissue, limb, organ or organ system of the body, much like a surgeon or pathologist might do in real life, but entirely non-invasively, without pain or destruction of tissue. These capabilities promise exciting new insights into the basic processes of life, and major advances in health care delivery through improved diagnosis and treatment of disease.

Computer Graphics↗

Hospital users rate software applications. 1990 SDR vendor awards of excellence.

Not all software packages are made the same; some do their jobs better than others. Which software is most popular among hospitals? The 1990 SDR Vendor Awards of Excellence is an attempt to answer that question. For the awards, Shared Data Research (SDR), Hudson, OH, asked hospital software users to nominate companies that produce the best-performing software.

Attitude of Health Personnel↗

Is there an optimal bibliographic software product for end users?

Personal bibliographic database software is one of many products being marketed to researchers. A review of the literature reflects a growing interest in using this software in office settings. Five bibliographic database software products are compared and eight important attributes are identified. We report experience in user training and in providing support by offering discounts on software sold through the library to patrons.

Information Systems↗

Languages, DBMSs, and expert systems. Software for nurse decision making.

This article sheds some light on the task of selecting software for decision making by nurse administrators. The basics of software are described, defining and distinguishing software, firmware, programs, languages, and systems (including database management and expert systems). A discussion of evolving trends and a short discussion of how to go about selecting software systems to meet your needs are included.

Administrative Personnel↗

Evaluation of body composition by dual energy x-ray absorptiometry and two different software packages.

Dual energy x-ray absorptiometry (DXA) measures body composition, tissue distribution, bone mineral content (BMC), and bone mineral density (BMD). Differences are possible due to software versions. This investigation examined body composition, tissue distribution, BMC, and BMD measurements using a DXA (Lunar Corp., Madison, WI) with different software packages (versions 3.4 and 3.6R). Fifteen women, ages 20-40 yr, enrolled in a weight-loss study (body mass index = 28) and volunteered for body composition assessment by densitometry. BMC, BMD, and tissue distribution measurements were made using DXA. Results were analyzed once each with software versions 3.4 and 3.6R. BMC + total soft tissue, measured using DXA, was comparable to measured body weight (3.4 = 76.3 kg; 3.6R = 76.5 kg; weight = 76.5 kg). Lower BMC and BMD (5.5% and 1.8%, P < 0.01) were observed with 3.6R. Arm tissue mass was lower (1,530 g; P < 0.01) and fat declined (1,069 g; P < 0.01) with 3.6R. Leg tissue mass decreased 487 g (P < 0.01), but fat tissue increased (526 g, P < 0.01) with 3.6R. A larger fat mass (1,492 g) and lower lean mass (1,115 g) were observed with 3.6R compared with 3.4. Percent fat values by densitometry using DXA 3.4 and 3.6R were 38.1%, 39.9, and 41.9%, respectively. These results demonstrated differences in total body composition, lean and fat tissue distribution, and bone measurements from DXA software versions.

Absorptiometry, Photon↗

Development and testing of computer software for nursing assessment and care planning at a spinal cord injury center.

This paper describes a pilot project using a Macintosh personal computer and customized software to computerize nursing admission assessment and care planning data. The project setting is a 47-bed Spinal Cord Injury Center with two inpatient units and an outpatient department serving approximately 1,000 patients with spinal cord injury at a Department of Veterans Affairs Medical Center in northern California. The computer software development, implementation, and evaluation are described. This software (MacNursing) was found to be a low cost, customized approach to computerizing spinal cord injury admission assessment data and care planning which reduces repetitive writing and facilitates continuity of care. Personal computers and this software have provided the mechanism for establishing a spinal cord injury patient database.

Humans↗

[The Cantonese dialect and mandarin speech audiometric software for computerized audiometer--a preliminary report of exploratory research].

The operation of computerized audiometer depends on softwares. Cassette tapes recorded with 4 Cantonese dialect and 6 Mandarin word lists, both monosyllables and spondees edited and recorded by the author in 1986 were utilized as an original sound source. Each Chinese character and its standard voice were re-edited and saved in computer by means of a Mac digitizing recorder and other computer technic to make a new software. The software is saved in seven 3.5" 2MB floppy dicks. Another copy now is saved in the hardware of a Virtual 320 audiometer at ENT department of Guangdong Provincial Traditional Medical Hospital for further quality checkout and clinical trials. It seems that the quality of this software mostly meets the requirements on recorded speech material suggested by ISO/CD 8253-3 1990.

Audiometry, Speech↗

Odontogenic cysts: improved imaging with a dental CT software program.

PURPOSE: To evaluate a dental CT software program to determine whether it can provide a better means of assessing odontogenic cysts, lesions of the jaw derived from dental epithelium, than conventional techniques (orthopantomographic, intraoral, and mandibular films), which are of limited usefulness because of the curved configuration of the mandible; and to provide a brief review of these lesions. METHODS: Nine odontogenic cysts were studied with conventional radiographs and with the software program, which displays multiple cross-referenced axial, panoramic, and cross-sectional (unique to this program) views of the mandible. The two modalities were compared for delineation of anatomy (inferior alveolar canal, mandibular foramen, mental foramen), detection of neurovascular bundle displacement, detection of cortical bone involvement, and detection of root involvement. RESULTS: The software program rated higher regarding all four points. It was found to be superior for delineating anatomy and detecting mandibular canal displacement and cortical and root involvement. CONCLUSIONS: This software program should be the study of choice when evaluating odontogenic cysts and other lesions of the mandible.

Adolescent↗