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Relation of tricuspid inflow E-wave peak velocity to severity of tricuspid regurgitation.

E-wave velocity in mitral flow has previously been shown to discriminate between severe and nonsevere mitral regurgitation. In this study, we sought to explore this association in the tricuspid position. The peak velocity of the tricuspid inflow E wave was measured in 118 patients (mean age 62 +/- 16.6 years; 48% women). Patients with tricuspid stenosis, transvenous pacemakers, and tricuspid prostheses were excluded. E-wave measurements were taken during shallow breathing. Tricuspid regurgitation (TR) was quantified as none or mild (group 1), moderate (group 2), or severe (group 3), according to American Society of Echocardiography guidelines. Forty-three patients had mild TR, 43 had moderate TR, and 33 had severe TR. Peak E-wave velocity was 48.6 +/- 13.8, 48.6 +/- 11.7, and 78.3 +/- 26.1 cm/s in groups 1, 2, and 3, respectively (p > 0.0001). Mean E-wave velocity was similar in groups 1 and 2 but greater in group 3 (p < 0.0001). A peak E-wave velocity of > or = 65 cm/s had a sensitivity of 73% and specificity of 88% for the detection of severe TR. In conclusion, increased peak tricuspid E-wave velocity is associated with severe TR and thus can be used as a simple measure of TR grade.

Blood Flow Velocity↗

Native cardiac disease predisposing to infective endocarditis.

Although no epidemiological studies are available to evaluate the exact risk of infective endocarditis complicating native cardiac disease, analysis of data in the literature shows that cardiac disease can be classified into three groups of decreasing risk: (1) high risk disease includes cyanotic congenital heart lesions, previous bacterial endocarditis, aortic valve disease, mitral regurgitation and uncorrected left-to-right shunt, but not atrial septal defect; (2) cardiac conditions of moderate risk include mitral valve prolapse with valvar regurgitation or leaflet thickening, isolated mitral stenosis, tricuspid valve disease, pulmonary stenosis and hypertrophic cardiomyopathy; (3) conditions of low or no risk include isolated atrial septal defect, ischaemic heart disease and/or previous coronary artery bypass graft surgery, surgically corrected left-to-right shunt with no residual shunt, mitral valve prolapse with thin leaflets in the absence of regurgitation, and calcification of the mitral annulus.

Causality↗

Comparison of Kay's and de Vega's annuloplasty in surgical treatment of tricuspid incompetence. Clinical and haemodynamic results in 62 patients.

This paper compares the late results of Kay's and de Vega's annuloplasty in the management of tricuspid incompetence. The operations were done in 62 consecutive patients during the nine-year period 1969-77 and included simultaneous correction of acquired valvular lesions (58/62) and congenital malformations (4/62). Kay's bicuspidalization and de Vega's annular plication were performed in 27 vs. 35 patients and these two groups were similar in the most important respects. Tricuspid regurgitation was recognized in 44/62 patients (71%) before surgery, whereas in 18/62 patients (29%) it was diagnosed at intra-operative exploration. The majority of cases (84%) were functional in origin and 16% had anatomical lesions causing or contributing to significant incompetence. Most of the patients (90%) belonged to functional class III or IV (N.Y.H.A.) before operation. The type of tricuspid repair had no bearing on early (11% vs. 14%) and late mortality (5.8%/year vs. 5.0%/year). Re-evaluation in 50 patients showed that Kay's bicuspidalization and de Vega's annular plication gave similar and good late result in about 70% of the cases. The risk of over-correction was low in that only 1/30 cardiac catheterization revealed signs of mild tricuspid stenosis. Recurrent or residual tricuspid incompetence is probably related to the severity of the individual cases. Some of these failures were evident already on the patient's discharge from hospital but, unfortunately, not predictable from the pre- or intra-operative evaluations.

Adolescent↗

[Risk of bacterial endocarditis and native heart diseases].

Although there are no epidemiological studies allowing precise evaluation of the risk of infective endocarditis in given cardiac pathologies, a review of the literature allows classification of different conditions in three groups of decreasing risk: 1: high risk group: cyanotic, congenital heart disease, patients with previous infective endocarditis, aortic valve disease, mitral regurgitation and unoperated left-to-right shunts apart from atrial septal defects; 2: moderate risk group: mitral valve prolapse with myxoid valves or a systolic murmur, mitral stenosis, tricuspid valve disease, pulmonary stenosis, hypertrophic obstructive cardiomyopathy; 3: low or negligible risk: isolated atrial septal defect, operated or unoperated (bypass graft) ischaemic heart disease, operated left-to-right shunts without residual shunt, mitral valve prolapse with normal valve thickness and without a murmur, mitral ring calcification without regurgitation.

Cardiomyopathy, Hypertrophic↗

Tricuspid valve surgery: 15-year experience.

Tricuspid valve surgery has been associated with a high operative mortality. This study reviewed 51 patients who underwent 53 tricuspid valve procedures between 1975 and 1989. Most patients (82%) had evidence of rheumatic heart disease. Twenty-six patients (51%) had 42 previous cardiac operations, most involving the mitral valve. Eighty-two percent of patients were New York Heart Association (NYHA) class III or IV preoperatively, and almost all patients had associated disease of other valves. The indication for operation was tricuspid regurgitation in 45 patients, infectious endocarditis in 4, and tricuspid stenosis in 2. The tricuspid abnormality was functional in 67% and organic in 33%. There were 32 tricuspid valve replacements, 20 annuloplasties, and 1 tricuspid valve excision. The hospital mortality rate was 11.8% (six patients). On statistical analysis, none of the perioperative variables were a significant risk factor for hospital mortality. Twenty-nine patients (51%) had postoperative complications. Postoperative functional status improved markedly with 80% in NYHA class I and 13% in class II. Long-term follow-up was attempted but was unsatisfactory in this transient, indigent population.

Adolescent↗

Doppler echocardiographic assessment of the valve area in patients with atrioventricular valve stenosis by application of the continuity equation.

The orifice area was non-invasively assessed in 19 patients with mitral or mitral and tricuspid stenosis by combined cross-sectional and Doppler echocardiography. Stroke volume was calculated as the product of aortic or pulmonic cross-sectional area and the time velocity integral of the flow across that valve, and the stenotic valve area was obtained as the stroke volume divided by the time velocity integral of the stenotic valve. In addition, the mitral valve area was estimated by the pressure half-time method of Hatle et al. The non-invasive determinations were compared with those calculated by the Gorlin formula at cardiac catheterization. The valve area obtained by combined cross-sectional and Doppler echocardiography showed a close correlation with the Gorlin area, r = 0.90, SEE = 0.13 cm2, n = 20. In contrast, the valve area estimated by the pressure half-time method showed only a moderate correlation with the Gorlin area, r = 0.68, SEE = 0.38 cm2, n = 18, and estimates by this method tended to significantly overestimate the Gorlin area. In conclusion, non-invasive valve area determinations based on combined cross-sectional and Doppler echocardiography can be used to accurately quantify the severity of the lesion in patients with atrioventricular valve stenosis, while determinations by the pressure half-time method may show errors of a magnitude that limits its clinical applicability.

Aged↗

Late results of combined percutaneous balloon valvuloplasty of mitral and tricuspid valves.

Although combined mitral and tricuspid stenosis are rarely seen in patients with rheumatic heart disease, when both exist together, combined percutaneous balloon valvuloplasty can be an alternative to surgical treatment in suitable cases. We present the immediate and late follow up results of 12 patients with rheumatic tricuspid and mitral stenosis treated with combined percutaneous balloon valvuloplasty. Twelve patients (11 female, 91.7%; 1 male, 8.3%) with a mean age of 35.3 +/- 6.4 years were enrolled in the study. The patients were followed up for 38.8 +/- 12.6 months. The mitral valve area increased from 1.2 +/- 0.2 cm2 to 2.3 +/- 0.2 cm2 (P < 0.01) and on follow up the mitral valve area did not differ significantly (2.2 +/- 0.2 cm2; P > 0.05). The tricuspid valve area increased from 1.6 +/- 0.3 cm2 to 3.2 +/- 0.2 cm2 (P < 0.01) and on follow up the tricuspid valve area did not differ significantly (3.1 +/- 0.2 cm2; P > 0.05). Two patients (16.6%) had tricuspid restenosis and tricuspid re-valvuloplasty. One other patient (8.3%) was referred to surgery 14 months after the procedure secondary to severe tricuspid regurgitation. In conclusion, this study demonstrates a sustained benefit on late follow up after combined percutaneous balloon valvuloplasty of mitral and tricuspid valves and confirms the efficacy and safety of the procedure as an alternative to surgery in selected cases of combined mitral and tricuspid stenosis.

Adult↗

Rheumatic aortic stenosis in young patients presenting with combined aortic and mitral stenosis.

This report describes 30 patients under the age of 30 years with rheumatic aortic stenosis, presenting with combined aortic and mitral stenosis. Three patients had additional tricuspid stenosis. Twenty-eight patients gave a history of rheumatic polyarthritis. The diagnosis was confirmed by right and left heart catheterisation in all. The murmur of aortic stenosis was not initially present in 8 out of 10 patients in congestive heart failure. Aortic valve calcification was not seen. Cineangiography showed a tricuspid aortic valve in all, unlike congenital aortic stenosis. A unique feature of this group was the raised pulmonary vascular resistance in 87 per cent of the patients. The present study shows that patients in India developing aortic stenosis after rheumatic fever do so early in the natural history of the disease.

Adolescent↗

Echocardiographic recognition of atrioventricular valve stenosis associated with endocardial cushion defect: pathologic and surgical correlates.

The association of either mitral or tricuspid stenosis with endocardial cushion defects has been well recognized pathologically but is infrequenctly diagnosed clinically. M mode echocardiographic features such as markedly disproportionate ventricular size, abnormal mitral or tricuspid diastolic echoes or failure to define adequately an atrioventricular (A-V) valve are strongly suggestive of associated stenosis of that valve. In this study mitral stenosis in association with endocardial cushion defect was correctly diagnosed in four of five patients. In the fifth patient (the first seen) the condition was easily diagnosed retrospectively. Tricuspid stenosis was similarly diagnosed prospectively in three of four patients. Significant stenosis was not overlooked or misdiagnosed in any patient with an endocardial cushion defect. Significant stenosis of an A-V valve in association with endocardial cushion defect carries a high mortality. It is important to recognize the combined lesion clinically because infants with it are not suitable for total surgical correction. Palliative surgical procedures with aggressive medical therapy probably offer the infant the best chance of surviving until ventricular growth may render corrective surgery feasible.

Aorta↗

Clinical and anatomic observations in patients having mitral valve replacement for mitral stenosis and simultaneous tricuspid valve replacement.

Certain clinical and morphologic findings are described in 67 patients (aged 23 to 76 years [mean 52]; 55 women [82%]) who had mitral valve replacement for mitral stenosis (with or without associated regurgitation), and simultaneous tricuspid valve replacement for pure tricuspid regurgitation (58 patients) or tricuspid stenosis (all with associated regurgitation; 9 patients). Of the 58 patients with pure tricuspid regurgitation, 21 had anatomically normal and 37 had anatomically abnormal (diffusely fibrotic leaflets) tricuspid valves. Among these 58 patients, no clinical or hemodynamic variable was useful before surgery in distinguishing the group without from that with anatomically abnormal tricuspid valves. All 9 patients with stenotic tricuspid valves had anatomically abnormal tricuspid valves. The latter group had a lower average right ventricular systolic pressure (tricuspid valve closing pressure) than those with pure tricuspid regurgitation, and none had severe pulmonary arterial hypertension (present in 20 [30%] of the 58 patients with pure tricuspid regurgitation).

Adult↗

Rheumatic tricuspid valve disease: two-dimensional echocardiographic, hemodynamic, and angiographic correlations.

From March 1977 through April 1982, 2-dimensional echocardiography detected 372 patients with rheumatic mitral valve disease. Of these patients, 23 (6%) had tricuspid valve involvement. Two-dimensional echocardiographic criteria of rheumatic tricuspid valve disease included thickened leaflets with restriction in motion, diastolic doming, and encroachment of the leaflet tips on the ventricular inlet. These criteria provided a sensitivity of 100%, a specificity of 90%, a predictive accuracy of 21%, and a negative predictive value of 100% in diagnosing hemodynamically significant tricuspid stenosis. Hemodynamic variables in patients with rheumatic tricuspid valve disease (Group I) were compared with those in patients with no rheumatic tricuspid disease (Group II). The only significant difference was mean right atrial pressure (15 +/- 7 mm Hg versus 11 +/- 5 mm Hg, p less than 0.02). Both groups were classified into patients with (A) and without (B) significant tricuspid regurgitation (TR). There was no significant difference in any hemodynamic variable when Group IA was compared with Group IIA. In addition, there was no difference in any hemodynamic variable when patients with functional TR (Group IIA) were compared with those with rheumatic mitral valvular disease without TR (Group IIB). Two-dimensional echocardiography and cardiac catheterization provide complementary diagnostic information in these patients.

Adult↗

Closure of isolated ventricular septal defect with detachment of the tricuspid valve.

Detachment of the septal leaflet of the tricuspid valve is an alternative technique for obtaining complete visualization of a perimembranous ventricular septal defect (VSD) in cases where the VSD is obscured by the chordae tendineae or a pouch formation of the septal leaflet. This method presents theoretical concerns because it has the potential for causing postoperative valvular insufficiency. We therefore evaluated valvular function in patients who underwent VSD closure with detachment of the tricuspid valve. In a consecutive series of 153 patients who underwent VSD closure using a transatrial approach, 13 had incision of the tricuspid valve. Follow-up echocardiographic studies were performed on these patients at least 1 year following operation. There were no operative deaths. Color Doppler echocardiography revealed no residual shunt in any of these patients. Ten patients had no evidence of tricuspid stenosis or regurgitation. One patient had trivial tricuspid regurgitation. Moderate tricuspid regurgitation was observed in two patients of these, one patient was a small infant who had a VSD complicated by pulmonary hypertension. The other patient had a VSD with a mitral cleft, pulmonary hypertension, and Down's syndrome. The incised tricuspid valve was resuspended by solely running sutures. In conclusion, detachment of the tricuspid valve is a safe and useful method for adequate exposure of a VSD. However, this method should be avoided in patients with Down's syndrome and in small infants. Furthermore, repair of the incised valve should not be performed using only running sutures.

Adolescent↗

[Echocardiographic evaluation of associated valve lesions in mitral stenosis].

OBJECTIVE: When mitral stenosis is associated with other valve lesions, diagnosis, prognosis and the treatment strategies are affected. Mitral valve prolapse may occur in some pathological settings that affect mitral apparatus. We investigated the incidence of valve lesions including mitral valve prolapse that accompany mitral stenosis and assessed the relation between echocardiographic measures. METHODS: Two hundred and one patients (31 male, 170 female) between 16 and 72 years of age (mean age 40.9+/-11.4 years) with mitral stenosis were included in the study. Patients were divided into three groups according to the mitral valve area obtained by echocardiography using planimetric method as Group I (MVA<1.1 cm(2)), Group II (MVA -1.1-1.5 cm(2)) and Group III (MVA >1.5 cm2). RESULTS: Mitral stenosis with mitral regurgitation, aortic regurgitation, aortic stenosis, combined aortic valve disease, tricuspid regurgitation and tricuspid stenosis were found in 117 (58.2%), 84 (41.8%), 18 (9%), 9 (4.5%), 62 (30.8%) and 6 (3%) patients, respectively. Twenty- three patients (11.4%) had mitral valve prolapse in only anterior leaflet. Nobody of patients had mitral valve prolapse of posterior mitral valve leaflet. Age, gender, rhythm, degree of stenosis, degree of mitral and aortic regurgitations, mean pressure gradient, left atrial diameter, ejection fraction and valve score did not differ in patients with and without mitral valve prolapse. CONCLUSION: Our study has shown that valve lesions including mitral valve prolapse frequently accompany mitral stenosis and the incidence of mitral valve prolapse in patients with mitral stenosis is high.

Adolescent↗

Non-invasive diagnosis and assessment of tricuspid regurgitation and stenosis using one and two dimensional echo-pulsed Doppler.

Twenty normal subjects and 82 patients with valvular heart disease, whose lesions were independently assessed either by cardiac catheterisation and/or at operation, were studied using the pulsed Doppler technique combined with either one or two dimensional echocardiography. Of these, 41 patients had tricuspid lesions, including 40 with regurgitation and nine with stenosis. The tricuspid analogue flow velocity trace and the Doppler frequency spectrum (time interval histogram) were recorded. Characteristic differences were found between the records from subjects with and without tricuspid lesions. In subjects with tricuspid regurgitation there was a systolic negative wave on the analogue velocity display and broadening of the time interval histogram. In subjects with tricuspid stenosis there was an abnormal pattern, and significantly increased duration of the diastolic wave on the analogue velocity trace, again with broadening of the time interval histogram. Sensitivity and specificity ranged between 85 and 95%. The calculated ratio between the measured amplitudes of the systolic and diastolic waves correlated well with independently performed grading of the regurgitation on a three point scale in 85% of cases. Grading of the severity of tricuspid stenosis on a three point scale based on studies of the diastolic Doppler velocity anomalies was the same in 85% of cases as the grading based on established invasive techniques. The addition of two dimensional echocardiography to the pulsed Doppler technique increased the sensitivity for mild lesions.

Adolescent↗

[Tumor of the tricuspid valve operated on with success. Apropos of a case simulating cyanotic heart disease].

The case of a 36 year old woman with a calcified tumour of the tricuspid valve is reported. The clinical signs suggested tricuspid stenosis with a right to left shunt via a patent foramen ovale simulating a cyanotic heart lesion. Preoperative diagnostic investigations were discordant. Echocardiography showed a stenotic tumoural tricuspid valve. Catheterisation and selective right ventriculography were more suggestive of dominant tricuspid incompetence. The patient was referred for surgery because of the severity of her shortness of breath and cyanosis, and tumoral involvement of the three tricuspid leaflets was found. This was removed and replaced by a bioprosthesis with good results 27 months after surgery. 17 other cases of tricuspid tumours have been previously reported. Their clinical presentation was usually that of a right ventricular tumour with stenosis of the right failure, positional syncope and pericardial effusion in the malignant forms. Signs of tricuspid stenosis with cyanosis and polycythaemia are very rare. The relative diagnostic values of angiography and echocardiography are discussed.

Adult↗

Is it open or is it closed? Thrombosis of a St. Jude's tricuspid valve prosthesis.

A 49-year-old woman with mitral and tricuspid mechanical valve prostheses developed marked weight gain with increasing abdominal girth and facial plethora 4 weeks after anticoagulation was temporarily interrupted for abdominal surgery. Transthoracic and transesophageal echocardiography documented severe tricuspid stenosis and regurgitation. The two discs of the tricuspid prosthesis were immobilized, half open and half closed. The prosthesis was replaced and the patient did well.

Echocardiography, Doppler↗