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The ISG viewing wand: an application to atlanto-axial cervical surgery using the Le Fort I maxillary osteotomy.

Surgical access to the clivus and upper cervical spine may be facilitated by a number of approaches. The Le Fort I maxillary osteotomy has been described to give improved access to the skull base for removal of tumours and treating vertebrobasilar aneurysms. We describe a case in which the combination of a particularly high translocation of the body of C2 and poor mouth opening had precluded a standard transoral approach by restricting access to the operative field. Anterior decompression of the body of C2 was therefore performed via a maxillary down-fracture with the aid of an interactive image guidance system, the ISG Viewing Wand. The ISG Viewing Wand is a new intra-operative 3 dimensional (3D) image guidance system which has now been used in over three hundred neurosurgical cases at Frenchay Hospital, Bristol. We briefly discuss the principles of the viewing wand and describe its unique application providing anatomical navigation in upper cervical spine surgery.

Aged↗

Cranio-vertebral pathology in Down syndrome.

Cranio-vertebral malformations, especially atlanto-axial dislocation, are frequently seen in Down patients. However, symptomatic forms in mongolism are rare. Pyramidal signs have a signal value. In symptomatic malformations surgical treatment should be advised, i.e. posterior fixation after pre-operative reduction by traction or transoral odontoidectomy if no reduction is achieved.

Adolescent↗

CT and myelogram findings of os odontoideum.

We reviewed the findings of CT and myelogram of cases of os odontoideum. The diagnosis was confirmed by conventional tomogram in all these cases. Four cases were further confirmed by trans-oral decompression. Cartilage was found between the os odontoideum and the odontoid process during operation in these 4 cases. Four of them had no history of trauma and 2 of them had an associated anomaly; one was Down's syndrome, and the other was barrel chest and congenital dislocation of hips. CT findings of os odontoideum in these cases were a constriction and/or a gap of bony structure between the os odontoideum and the odontoid process. Myelograms showed spinal stenosis as a result of atlanto-axial dislocation, or anterior extradural compression from overgrown cartilage and posteriorly dislocated tip of shortened odontoid process.

Adolescent↗

A study of radiologic imaging techniques and airway grading to predict a difficult endotracheal intubation.

STUDY OBJECTIVES: To study whether a detailed radiographic examination of neck and upper airway can help identify normal looking patients in whom endotracheal intubation may be difficult; determine whether such parameters as identified by magnetic resonance imaging (MRI) can also be identified in a soft tissue radiograph; and to study the correlation between oropharyngeal appearance, based on Mallampati's classification, and laryngoscopic findings in a large number of patients requiring endotracheal intubation. DESIGN: Prospective. SETTING: University medical center. PATIENTS: 20 adult patients in whom an unanticipated difficult endotracheal intubation was encountered, and a control group of 20 patients in whom endotracheal intubation was easily accomplished. INTERVENTIONS: Difficult-to-intubate patients were identified according to prospectively established criteria. Control subjects, in whom the trachea was easily intubated, were matched for age, gender, height, weight, and oropharyngeal appearance. MEASUREMENTS AND MAIN RESULTS: In all 40 study patients, a soft tissue radiograph and an MRI scan of the neck were obtained. We measured 21 parameters from both radiographic studies. There were no significant differences between the two groups in 20 of 21 measured parameters on MRI scans and soft tissue radiographs. Only one measurement--the distance between the uppermost visible part of the airway and the posterior pharyngeal wall (measured from MRI scans only)--between the two groups achieved statistical significance. The values recorded from MRI and soft tissue radiographs were not significantly different. Airway grading system first suggested by Mallampati had a fair correlation with laryngoscopy findings associated with a difficult endotracheal intubation. CONCLUSIONS: No significant difference between the two groups could be identified on soft tissue radiography or MRI scans.

Adult↗

Anterior approach to traumatic mid aortic arch transection.

The majority of nonpenetrating traumatic injuries to the thoracic aorta are fatal. Survivors of aortic transection tend to have injuries occurring at the isthmus. We report a rare, blunt traumatic complete transection of the mid aortic arch between the innominate and left common carotid arteries diagnosed by multidetector computed tomography of the chest. The repair was approached anteriorly and required aortic arch replacement.

Accidents, Traffic↗

Anterior cruciate ligament rupture translates the axes of motion within the knee.

OBJECTIVE: To quantify the dynamic effects of anterior cruciate ligament deficiency on human knee joint motion. DESIGN: Three-dimensional motion was assessed by measuring the kinematics of intact and anterior cruciate ligament deficient knee joint specimens during simulated flexion-extension cycles. BACKGROUND: It is known that the anterior cruciate ligament plays an important role in controlling three-dimensional knee joint motion. Nevertheless, dynamic effects of deficiency are not fully understood. METHODS: Six cadaveric knees were tested in a knee joint motion and loading apparatus prior to and after anterior cruciate ligament resection. To determine if the kinematic results depended on additional loading, internal and external rotation moments of 3.4 Nm were axially applied to the tibia. The kinematics were analysed in terms of finite helical axes. RESULTS: Sectioning the anterior cruciate ligament had little effect on the orientations of the finite helical axes. However, applying moments did affect the axes orientation. In contrast, relative translations of the axes were significantly affected by the deficiency for all rotational moments applied. Referring to the individual knee anatomy the largest translation of 12.5 mm (median) occurred in medial/lateral direction. CONCLUSIONS: Anterior cruciate ligament rupture primarily causes a translation of the finite helical axes in medial/lateral direction. Consequently, increased anterior excursion of the tibia occurs (subluxation) and therefore dynamic instability.

Adult↗

Pedicle fracture of the axis: report of two cases and a review of literature.

Clinical and neuroradiological features of two cases with unilateral pedicle fractures of C2 were presented and the literature of this rare traumatic fracture was reviewed. Both 37- and 57-year-old woman had traffic accident and were admitted in our institute. Both patients were neurologically free except for neck pain. Plain X-ray of cervical spine did not show abnormal findings. Computerized tomography (CT) with bone window showed the location and extension of the traumatic fracture in C2 pedicle. The fracture was located in the portion between the lateral border of the odontoid process and pars interarticularis. Fractures of the C2 pedicle are rarely seen in acute traumatic fractures. They can be overlooked because there is confusion in the describing of anatomical location of C2 pedicle in some medical literature. For proper diagnosis of pedicle fracture of the axis, understanding of the anatomy of C2 and CT findings with bone window are important.

Adult↗

First spinal axis segment irradiation with spot-scanning proton beam delivered in the treatment of a lumbar primitive neuroectodermal tumour. Case report and review of the literature.

Primary intraspinal primitive neuroectodermal tumour (PNET) is a rare tumour entity. The optimal therapeutic management is unclear but, in general, this tumour is treated with surgery followed by radiotherapy and chemotherapy. Proton beam radiation therapy (PT) offers superior dose distributional qualities compared with X- or gamma rays, as the dose deposition occurs in a modulated narrow zone called the Bragg peak. As a result, organs at risk are optimally speared. Here, we present a patient treated with the first spinal axis segment irradiation using spot-scanning PT with a single field, combined with conventional cranio-spinal axis radiotherapy after surgery and chemotherapy, and an extensive review of the literature outlining the clinical features and treatment modality of spinal PNET.

Adult↗

Palpatory diagnosis of plagiocephaly.

INTRODUCTION: The term plagiocephaly, from the Greek plagios (oblique) and kephalê (head), means distortion of the head, and refers clinically to cranial asymmetry. Cranial Osteopathy, since it was first proposed, has focussed upon the diagnosis and treatment of birth trauma and cranial asymmetries, and consequently specific therapy for plagiocephalic deformities has been described. Osteopathic manipulation also has been proposed as a treatment for torticollis, a condition associated with plagiocephaly. For these reasons, we decided to look at the mechanics of the occipital bone and the adjacent atlas and bones of the cranial base, in relation to functional plagiocephaly. METHODS: The records of 649 children seen in an osteopathic practice in Lyon, France, were reviewed retrospectively, in compliance with the legal requirements of the Commission Nationale de l'Informatique et des Libertés (CRIL) and the Helsinki accord, for gender, age at presentation, birth history, obstetrical data (breech presentation, vacuum extraction, forceps delivery or Caesarean section), presenting complaint, side of posterior plagiocephaly, side of frontal plagiocephaly, torticollis, motion pattern of the occipital bone upon the atlas, and motion pattern of the spheno-occipital synchondrosis. RESULTS: We found significant correlations between plagiocephaly (right/left) and primipara (P=0.024), use of forceps (P=0.055) and extractor suction (P=0.055). Correlations were also found between flattening of the occiput (right/left) and lateral strain of the spheno-occipital synchondrosis (P=0.002) and between plagiocephaly (right/left) and occipito-atlantal motion (P=0.000). CONCLUSION: We found a significant correlation between the lateral strain pattern of the spheno-occipital synchondrosis and plagiocephaly and between rotational dysfunction of the occiput upon the atlas and the side of posterior plagiocephaly. We suggest that thorough neonatal osteopathic examination can identify individuals predisposed to develop posterior plagiocephaly.

Atlanto-Occipital Joint↗

A simple technique for craniospinal radiotherapy in the supine position.

PURPOSE: Craniospinal irradiation poses technical difficulties that may be addressed with the use of the newer technologies that have become available over the past decade. The use of CT simulation allows improved target localisation and beam geometry definition while significantly reducing the treatment simulation time. We have developed a CT-based technique for whole CNS irradiation in the supine position that uses fixed field parameters, asymmetric jaws for field matching and drastically reduces simulation and treatment times. METHODS: The patient is CT scanned and treated in the supine position. The clinical target volume and relevant critical structures are outlined on a planning CT scan. Half beam blocked lateral fields with a collimator rotation are used to match the beam divergence from the superior border of the spinal field at the C2 vertebral body. The shielding for the cranial fields is generated automatically, and the dose distribution is calculated using a 3D treatment planning system. Fixed field parameters are used for the planning and treatment. The position of the isocenter of the spine field is always a fixed longitudinal distance from the isocenter of the brain fields. If multiple posterior fields are required, the isocenter of the second spine field is always a fixed longitudinal distance from that of the first and the gap between the fields is determined using virtual simulation and feathered during treatment using the asymmetric jaws of the linear accelerator. All treatment portals are filmed daily during the first week of treatment, and after each junction change thereafter. RESULTS AND CONCLUSION: The supine position provides numerous advantages. Patients are more comfortable, the treatment position is more reproducible, and access to the airway is possible, if necessary, for patient sedation. The use of CT simulation decreases the simulation time, allows for increased planning accuracy, and enables the use of multimodality image registration, and 3D treatment planning. The use of asymmetric jaws allows for junction feathering without changing the patient setup or using a couch angle.

Axis, Cervical Vertebra↗

Unusual presentations of craniovertebral junction tuberculosis: a report of 2 cases and literature review.

BACKGROUND: CVJ tuberculosis is a described entity requiring challenging ways of management. Severe neck pain, causing restricted neck movements and torticollis, is a characteristic presentation of neurologically asymptomatic suboccipital Pott's disease. CASE DESCRIPTION: Two patients with unusual CVJ tuberculosis form the basis for the present communication. The first patient presented with tubercular otitis media, causing progressive erosion of the petrous part of temporal bone, and destruction of the occipital condyle, along with the lateral mass of atlas, leading to CVJ instability. This is a first report of such a presentation, according to our knowledge. Detailed bony architectural destruction demonstrable on CT scan has been described. The second patient, with CVJ tuberculosis, presented with skull base syndrome and with multiple cranial nerve palsies. Both patients were managed without surgical intervention and showed clinical and radiological recovery. CONCLUSION: In such patients with unusual clinical presentations, histopathologic examination is necessary to arrive at a correct diagnosis. The management of patients with tubercular involvement of CVJ remains controversial. In the present communication, both the patients were managed successfully with full dose of antitubercular drugs and immobilization.

Adult↗

Halo traction in basilar invagination: technical case report.

BACKGROUND: In the management of basilar invagination, traction therapy may help by pulling down the odontoid process away from the brain stem that may result in clinical and radiological improvement. We aimed to discuss the role of the halo vest apparatus traction on the reduction of severe anterior compression pathologies in basilar invagination. CASE DESCRIPTION: We describe a simple and safe cervical traction method by the halo vest apparatus that is followed by rigid posterior occipitocervical fixation and foramen magnum decompression in a patient who presented with basilar invagination and symptoms of severe brain stem compression. An MR-suitable halo vest apparatus was used for reduction of the deformity. The reduction of the basilar invagination was achieved gradually by distracting the halo crown in stages. CONCLUSION: The halo vest apparatus can be safely used in complex craniocervical junction anomalies. An effective cervical traction can be performed in basilar invagination, and reduction of the deformity may be achieved without the risk of overdistraction. In some cases, even partial reduction of the deformity may facilitate brain stem and spinal cord relief without any need of posterior decompression. Patients may benefit from ambulatory functions because bed rest is eliminated in this procedure. Neurovascular structures and the degree of the reduction can be observed on MRIs when an MR-suitable device is used.

Atlanto-Axial Joint↗

Intraoperative dynamic angiography to detect resolution of Bow Hunter's syndrome: Technical case report.

BACKGROUND: Bow Hunter's syndrome is a rare form of vertebrobasilar insufficiency that may be successfully treated by surgical intervention. Use of intraoperative dynamic transcranial Doppler ultrasound for surgical treatment of vertebrobasilar insufficiency has been described in literature. However, this technique was inconsistent and unreliable in some patients. We present a case of a patient with Bow Hunter's syndrome treated surgically and emphasize the valuable addition of intraoperative dynamic angiography to determine resolution of vertebral artery compromise. CASE DESCRIPTION: The patient was a 58-year-old man with complaints of dizziness, vertigo, and near-syncopal episodes that occurred when he rotated his head to the left. Imaging revealed compromise of the dominant left vertebral artery with leftward head rotation. An anterior cervical approach with decompression of the left subaxial vertebral artery was performed. Significant osteophyte formation was observed. Removal of bone and decompression of the vertebral artery was performed. Intraoperative dynamic angiography confirmed resolution of vertebral artery compression and minimized the amount of decompression. No further intervention was required. CONCLUSION: Intraoperative dynamic angiography is a definitive test to determine hemodynamic resolution of Bow Hunter's syndrome. It offers real-time feedback of vertebral artery decompression, potentially minimizes the amount of decompression, and can be performed safely.

Axis, Cervical Vertebra↗

Hox genes, homology and axis formation--the application of morphological concepts to evolutionary developmental biology.

This article focuses on the interphyletic comparison of gene expression patterns. By means of the hypothesis of the inversion of the dorsoventral axis during the evolution of the Bilateria, it is demonstrated, that evolutionary developmental biologists use similarities in spatial and temporal gene expression patterns as evidence for the formulation of hypotheses of homology concerning either developing structures or body regions. The molecular genetic and morphogenetic evidence used is discussed within the framework of a cladistic-phylogenetic analysis based on the phylogenetic tree of the Bilateria. I argue that similarity of spatial and temporal gene expression patterns is not a sufficient criterion for homology inference. Therefore, gene expression patterns should be coded as characters. Their homology should be tested in concert with other characters. Furthermore, it is demonstrated, that spatial and temporal similar gene expression patterns, indicating similar molecular genetic mechanisms, were interpreted as an analytical criterion of homology, offering the possibility to identify similar structures. In contrast to this, the evolutionary developmental biologists have not developed a causal-analytically extended concept of shape, from which a causal-analytical concept of homology could be deduced. Instead, the homology concept from evolutionary morphology is used.

Animals↗

[Brain abscess following the use of skull traction with Gardner-Wells tongs].

Brain abscess after insertion of skull traction is a rare and serious complication. Its development is secondary to superficial infection. Adequate preventive measures have to be taken: proper sterile dressing and daily care. Signs of local irritation are not always synonymous with skull migration. When gradual loosening of the skull occurs, especially associated with superficial infection, the pins must not be tightened. The more appropriate management is to investigate for penetration of the inner cranial cave. When in doubt, repositioning the pins may be necessary, as well as establishing an aggressive treatment against cutaneous infection.

Adult↗

Clinical reliability of posterior fossa scintigraphy.

Radioisotope imaging of the brain is considerably less useful in posterior fossa lesions than in supratentorial diagnosis, due to the peculiar technical difficulties and biological characteristics of infratentorial lesions. Exceptions are acoustic neurofibromas and probably meningiomas, which can be reliably detected. The importance is stressed of making skull and chest radiographs at the time of the examination, in order to enhance the diagnostic accuracy of the scintigraphic result.

Axis, Cervical Vertebra↗

The odontoid process in children--is it hypoplastic?

An analysis of the cervical spine of 508 normal children aged between 3 and 18.9 years provided data for the normal development of the odontoid process and its relationship to the anterior arch of the atlas. In normal children under the age of 9 years, the tip of the odontoid may fall well short of the upper margin of the anterior arch of the atlas. This has important implications for the assessment of atlanto-axial instability in children with Down's syndrome.

Adolescent↗