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Glandular odontogenic cyst (sialo-odontogenic cyst): report of two cases and literature review of 45 previously reported cases.

The clinical, radiological, histopathological and immunohistochemical (cytokeratin) features of two cases of glandular odontogenic cyst (GOC) are presented and discussed in a review of 45 cases of GOC hitherto reported. Of cases with available information, 34 occurred in the mandible and 6 in the maxilla; the male:female ratio was 19:28, and the mean age was 46.7 years in males and 50.0 years in females. Six cysts recurred once after 2-8 years (mean 2 years 8 months) and 2 (5.3%) recurred twice after 2 and 5 years and after 3 and 5 years, respectively, giving a rate of recurrence of 21%. The identification of osteodentin in one of the present cases and the co-expression of cytokeratins (CK) 13, 19 and 8 strongly support the concept of odontogenic differentiation in the GOC. Careful surgical removal of the lesion succeeded by a 5-year follow-up period is recommended.

Adult↗

Is a cystic lesion located at the midline of the prostate a müllerian duct cyst? Analysis of aspirated fluid and histopathological study of the cyst wall.

OBJECTIVE: In 6 patients, ranging in age from 26 to 71 years, we analyzed aspirated fluid and histologically studied cystic lesions located at the midline of the prostate. METHODS: Digital rectal examination, ultrasonography, magnetic resonance imaging, and aspiration of cystic fluid were performed to evaluate size, contents, and location of the cystic lesion. A 22-gauge needle was inserted into the cystic lesion perineally under ultrasound guidance. After extracting fluid for cytology and measurement of prostate-specific antigen (PSA) and prostatic acid phosphatase (PAP), a specimen from the prostate involving the cystic wall was collected. Hematoxylin-eosin staining and immunohistochemical staining for PSA were performed. RESULTS: All aspirated fluid specimens were yellowish and clear without any sperm or malignant cells. The PSA levels in the fluid ranged between 90 and 670 x 10(4) ng/ml, while the PAP levels were between 168 and 4,000 ng/ml. These levels of PSA and PAP were significantly higher as compared with those in the serum. The cystic wall was lined with cuboidal or columnar epithelium. Some epithelial cells from the cystic wall showed positive immunostaining for PSA. CONCLUSIONS: Not all cystic lesions located at the midline of the prostate are müllerian duct cysts, and there is a high probability that the lesion could be a cystadenoma or a simple cyst of the prostate.

Acid Phosphatase↗

Familial renal agenesis and urogenital malformations. Seminal vesicle cyst and vaginal cyst with bicornuate uterus in siblings.

A seminal vesicle cyst was found in a 30-year-old man with ipsilateral renal agenesis. His sister had embryologically analogous malformations--Gartner duct cyst, bicornuate uterus and renal agenesis. This seems to be the first reported familial occurrence of these combined malformations. The embryogenesis is reviewed and the diagnostic procedure and treatment are discussed.

Abnormalities, Multiple↗

Popliteal cysts (Baker's cysts) in adults. II. Capsuloplasty with and without a pedicle graft.

In 15 adult patients, undergoing surgery for symptomatic popliteal cysts of fairly long duration, the communication into the joint was closed by two different procedures: In the early series, Series A (8 patients), the opening was tightly sutured, and in Series B (7 patients) a new type of capsuloplasty was performed, using a proximally based flap from the gastrocnemius tendon for additional reinforcement. One minor postoperative complication occurred in Series A, whereas all patients in Series B made an uneventful recovery. The results were assessed clinically and arthrographically almost 2 years postoperatively. All patients were relieved of their popliteal symptoms. In Series A three clinically asymptomatic recurrences were found at arthrography. No recurrence occurred in Series B (the capsuloplasty series). A modified postero-medial approach facilitated access to the communication. Postoperative immobilization for 3 weeks promotes uneventful healing of the capsular repair. The importance of meticulous closure of the gap is emphasized, whereas radical excision of the cyst does not seem essential for the therapeutic result.

Adult↗

Calcifying odontogenic cyst--Gorlin's cyst--report of two cases.

The authors present two cases of calcifying odontogenic cysts, which were confirmed by histological examination. In the first case the radiographic findings and clinical status did not indicate the presence of a calcifying odontogenic cyst. In the second case, differential diagnosis included COC. The histopathological findings showed that what appeared to be simple cases of bone translucencies was in fact an unusual odontogenic lesion. The two cases point out the possibility of incorrect assessment of deceptively banal cases in daily specialist practice.

Adult↗

Complete resection of choledochal cyst with Roux-en-Y derivation vs. cyst-enterostomy as standard treatment of cystic disease of the biliary tract in the adult patient.

BACKGROUND/AIMS: Cystic disease of the biliary tract (CDBT) is characterized by varying degrees of dilatation of the biliary system with high morbidity and mortality in which the surgical management is the corner stone of treatment. The cyst-enterostomies (CE) temporarily solve the obstruction to the biliary flow but have a high long-term morbidity. Complete resection of affected bile ducts with Roux-en-Y derivation (CRR-en-Y) is a good procedure with low mortality and complications. The purpose of the study was to analyze the outcome of CRR-en-Y versus CE in the treatment of CDBS in adult patients from 1970 to 2002. METHODOLOGY: Patients who underwent surgical treatment were divided for their analysis into two groups: Group I: CRR-en-Y and Group II: CE. Following features were compared: demography, clinical picture, postoperative morbimortality, outcome and survival. RESULTS: Thirty-four adult patients were analyzed. There were 82% (28) females and 18% (6) males. The age average was 33.58 years (13-84). Seventy percent (30) were "choledochal cyst". Eighty percent (27) were surgically handled: 52% (14) with CRR-en-Y (Group I) versus 58% (13) with CE (Group II). Both groups were comparable. Without operative mortality and low postoperative morbidity in both, CE had more long-term complications: In this group 70% (9) were readmitted: and 7 underwent reoperation. Mean follow-up was 35 months (6-132) versus 152 months (12-408) respectively. CONCLUSIONS: CRR-en-Y is the standard treatment of CDBS in the adult patient.

Adolescent↗

Cysts and cyst-like lesions of the skin and subcutaneous tissue.

Cysts and cyst-like lesions are common occurrences seen in a busy plastic surgical practice. Although many can be treated by surgical excision, they still represent an interesting histologic, etiologic, embryologic, and clinical spectrum. In a number of instances, they require detailed multidiagnostic evaluation and complex surgical approaches to excision. By classifying these cystic masses by age group and anatomic location, the clinician can simplify his or her approach to this group of cutaneous masses.

Adult↗

[Bronchogenic cysts and their atypical localizations. A case of pleuro-diaphragmatic cyst].

Bronchogenic cysts represent about 10 p. 100 of all surgical tumours of the mediastinum. They can never be diagnosed with absolute certainty prior to the operation, but when they arise in their typical sites, they can be suspected with a high probability. However, they can occur in very atypical sites, in which case the diagnosis remains very hypothetical until the operation. The authors report a case of a cyst which developed under the diaphragmatic pleura, in direct contact with the dome of the diaphragm and attached to the mediastinum by a fine vascular pedicle which inserted in the root of the triangular ligament.

Adult↗

Childhood choledochal cyst with intrahepatic enlarged cyst-like bile ducts.

A five-year-old boy was investigated for intermittent, crampy abdominal pain over several months. His abdomen was distended. Hepatomegaly and cystic masses were demonstrated in both lobes of the liver on ultrasound and computed tomographic examinations. An operative cholangiogram revealed a choledochal cyst of the cystic duct with massive dilatation of intrahepatic and extrahepatic bile ducts. After resection of the choledochal cyst and anastomosis of the jejunum to the common bile duct, the hepatic ducts have become near normal.

Child, Preschool↗

Choledochal cyst: personal experience in the management of choledochal cyst.

Choledochal cysts are uncommon in Zambia, but are frequently misdiagnosed and consequently mistreated. It is recommended that anastomotic drainage of the cyst into the duodenum or jejunum should be done as a first stage procedure on severely sick patients seen in rural hospitals, prior to their transfer to major hospitals where definitive procedure such as end to end anastomosis of the common bile duct or Roux-en Y choledochojejunostomy can be performed. Our experience of five cases seen over seven years is reported.

Adolescent↗

[Choledochal cysts. Review and presentation of 2 girls with perforated cyst].

The clinical record is reported of two female girls, 4 1/2 and 5 1/2 years old, who were reported in 1988 at the Children's Hospital in this City with diagnosis of perforated Cholodochal supurated cyst and who were asymptomatic when they left the hospital. It is mentioned that another four patients had been operated in the same hospital, between 1981 and 1987, with choledochal cyst diagnosis.

Child↗

Levels of eighteen non-conjugated and conjugated steroids in human breast cyst fluid: relationships with cyst type.

The present study investigates the levels of a large series of 18 non-conjugated or conjugated steroids in 71 samples of human breast cyst fluid (BCF) as divided into three groups corresponding to different electrolyte composition. In the type 1 group, the K+/Na+ ratio was higher than 1.5, while in type 2 it was lower than 0.66 and finally type 3 had an intermediate ratio. Pregnenolone (PREG) and progesterone (PROG) levels were approximately 2-fold higher (P less than 0.05) in the type 2 than in the type 1 group while both 17-OH-pregnenolone (17-OH-PREG) and 17-OH-progesterone (17-OH-PROG) concentrations were similar in these two groups. Most of the C-19 steroids analyzed, namely dehydroepiandrosterone sulfate (DHEAS), androst-5-ene-3 beta, 17 beta-diol (5-ene-DIOL), testosterone (TESTO), dihydrotestosterone (DHT), androstane-3 alpha, 17 beta-diol (3 alpha-DIOL), androsterone (ADT), androstane-3 alpha, 17 beta-diol glucuronide (3 alpha-DIOL-G) and androsterone glucuronide (ADT-G) were 180-360% (P less than 0.05) higher in type 1 than in type 2 cysts while no difference in C-18 steroid and C-18 steroid glucuronide levels was observed. A small or no difference was seen in steroid levels between types 2 and 3. We conclude that the arbitrary division according to the electrolyte composition of BCF permits identification of different patterns of steroid concentrations in BCF. However, the mechanism responsible for both sets of parameters remain unclear.

Adult↗

Intraosseous and extraosseous calcifying odontogenic cyst (Gorlin cyst).

This retrospective study of 15 central and five peripheral calcifying odontogenic cysts (COCs) was undertaken to compare the characteristics of these two lesions. The data reveal that the central COCs were more common than peripheral lesions by a 3:1 ratio and that they were usually diagnosed in the second decade of life, whereas the peripheral ones were usually noted after the age of 50. Seven of the 15 central COCs (47%) were associated with odontomas, and three (20%) with dentigerous cysts. Conservative enucleation or excision was the treatment of choice.

Adolescent↗