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At least 397 records · Page 22Linked to original sources

Two horizontal rectus eye muscle surgery combined with botulinum toxin for the treatment of very large angle esotropia. A pilot study.

PURPOSE: To evaluate the effectiveness of a proposed new protocol for the primary treatment for very large angle esotropia: two muscle horizontal rectus muscle surgery with simultaneous botulinum toxin A injection in a small pilot study. METHODS: Eight patients who had esotropia at near (ET') greater than 60 prism diopters (in actuality 70 to 100 prism diopters ET') underwent 2 muscle horizontal rectus surgery with simultaneous botulinum toxin A injection of the medial rectus intraoperatively. This was the only surgical procedure for all patients included in this report. Seven patients underwent bilateral medial rectus recession and bilateral injection, and one patient underwent a unilateral medial rectus recession / lateral rectus resection procedure with unilateral medial rectus injection. RESULTS: Postoperatively, 6 of the 8 patients demonstrated residual esotropia at near of less than 10 prism diopters and were considered "successful" by the conventional criteria of binocular alignment within 8 prism diopters of orthotropia. Two undercorrections occurred in patients with 100 and 85 prism diopters of preop ET' respectively. But 3 other patients with such large deviations had satisfactory results. All patients and families were satisfied with postoperative binocular alignment, so no further surgery was undertaken. The patient who underwent unilateral surgery had the least surgical effect and was the largest undercorrection, probably because only one medial rectus received a Botox injection. Considering only the bilateral cases, results were "successful" in 6 of 7 cases. Most patients suffered an extended period of Botox induced exotropia in the postop' period before recovery from the paresis. One patient had a transient, successfully treated, postoperative strabismic amblyopia while exotropic. CONCLUSIONS: Bilateral medial rectus recession with simultaneous botulinum injection is a safe and effective primary surgical procedure for very large angle esotropia. A more extensive study is indicated to confirm these findings.

Adult↗

A study to determine: should conventional amounts of eye muscle surgery for horizontal binocular deviations be changed when oblique muscle weakening procedures are simultaneously performed?

PURPOSE: To investigate the final surgical outcome in horizontal strabismus correction, measured in primary position of gaze, in two situations: 1. When surgery was performed only on the horizontal rectus muscles; and 2. When inferior or superior oblique muscle weakening procedures were simultaneously performed. METHODS: Two hundred thirty cases were analyzed retrospectively: 172 esotropias (110 without oblique overaction; 23 with inferior oblique overaction; and 39 with superior oblique overaction), and 58 exotropias (25 without oblique overaction; 19 with inferior oblique overaction; and 14 with superior oblique overaction). Initial and final deviations, as well as the amount of correction achieved, was compared in six groups. RESULTS: No differences in outcomes and final results were found between any of the major or minor groups of patients. CONCLUSIONS: Oblique muscle weakening, in combination with horizontal muscle strabismus surgery did not affect the final results of the horizonal surgery in primary position. This study did suggest that there might not be a need for increasing or decreasing amounts of surgery on the horizontal rectus muscles to correct eso- or exotropia when oblique weakening procedures are included.

Esotropia↗

Quantitative electron-microscopy analysis of cranial nerves III, IV, and VI and of the extrinsic eye muscles in fog.

A comparative study of the quantitative data of the frog extraocular muscles and the cranial nerves that innervate them was performed. Oculorotatory muscles contain muscle fibres of at least 4 types which are arranged in heterogeneous layers. The zonal arrangement of the muscles does not occur on the cross-sections in the vicinity of muscle insertions. In these regions only two muscle fibre types are present and the total number of fibres is smaller by 70% than in the central region of the muscle. Most numerous are muscle fibres in the rectus inferior muscle, while the smallest number of fibres is found in rectus interior muscle. Three distinct types of nerve fibres are distinguished according to the following criteria: occurrence and thickness of myelin sheath, fibre diameter and ratio "g". The fibres with thin myelin sheaths indicate small diameters (1-5--6- mum) and their ratio "g" equals 0-82 +/- 0-08. They constitute about 30% of the myelinated fibres in the nerve supply of the oculorotatory muscles and about 14% in the supply of the retractor bulbi muscle. Both the value of the ratio "g" and a greater number of these fibres in the nerve supply of the muscles that contain slow contracting muscle fibres indicate that they are rather slow conducting nerve fibres. The range of the diameters of the fibres with thick myelin sheaths is greater (3-5--13-5 mum) and their "g" equals 0-66 +/- 0-06. These fibres constitute about 70% of the myelinated ones in the nerve supply of the oculorotatory muscles and 86% in the supply of the retractor bulbi muscles. The value of the ratio "g" in these fibres indicates that they are fast contracting ones. The smallest diameters are found in the myelinated fibres (0-5--1-7 mum). These fibres occur frequently in all the examined nerves; they constitute 36--47% of the total number of all the nerve fibres. The frog extraocular muscles are characterized by an abundal nerve supply which is reflected in the low innervation ratio (1:4--1:5). On the distal cross-section of nerves the number of nerve fibres is greater than on the proximal ones. Ganglionic neurons occur sporadically around the nerves; in the nerve III synaptic contacts between two neurons were observed.

Abducens Nerve↗

Use of Healon in eye muscle surgery with adjustable sutures.

Adhesions between the contacting surfaces of conjunctiva, Tenon's capsule, and muscle produce "tissue drag" which can complicate procedures with adjustable muscle sutures. The use of Healon is recommended to minimize this tissue drag and facilitate the "adjustment phase" of muscle surgery with adjustable muscle sutures. Data on 14 consecutive cases demonstrate the utility of Healon in adjustable strabismus surgery.

Connective Tissue↗