PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Fetal Development”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 397 records · Page 22Linked to original sources
PubMed1995

[The human fetal development time table of the major limb bones-ultrasonic bone age].

B-ultrasonic technique was used to examine 297 Chinese fetuses in normal pregnancy woman of completed week age from 12 to 38 weeks. The lengths of the major limb bones were measured and statistical analysis showed that the positive linear correlation between the development of fetuses' limb bones and the completed fetal age is significant.

Bone Development↗
PubMed1992

Fetal heart rate response to acoustic stimulation in relation to fetal development and hearing impairment.

In twelve healthy pregnant women the fetal heart rate response to sound stimulation was tested every second week between the 22nd and the 34th week of the pregnancy. Habituation to the acoustic stimuli used was also investigated at the last examination. A high risk material for hearing impairment comprised 31 pregnant women. The stimuli were presented by a vibrator placed on the maternal abdomen over the fetal head. As stimuli pure tones were used in the form of pulses of one second at a frequency of 3000 Hz and with an onset and a decay time chosen not to cause audible clicks to a normal ear. The intensity of the tone pulse was set at a level calculated to correspond at the position of the fetal head to 110 dB sound pressure level in free field. Roughly 50% of the fetuses tested started to react with an increased heart rate in the 24th week of the development. Four weeks later all tested subjects responded to the test stimuli. Habituation of the motor 'startle' response was shown but the fetus heart rate change was consistent over 20 consecutive stimulations one min in between each. In 31 high risk subjects the responses from three fetuses must be considered as pathologic. These three children exhibited impaired auditory tests after birth and severe hearing impairment at the age of three years. All the others disclosed normal hearing at birth as well as at three years of age. Repeated significant increases in fetal heart rate following acoustic stimulation may appear as an indication of normal function of the hearing organ.(ABSTRACT TRUNCATED AT 250 WORDS)

Acoustic Stimulation↗
PubMed1991

Expression of prostaglandin G/H synthase (cyclooxygenase) during murine fetal thymic development.

Fetal thymic lobes in organ culture have been shown to have the capacity to metabolize [14C]arachidonic acid (AA) to prostaglandins (PGs), including 6-ketoPGF1 alpha, PGF2 alpha, PGE2, and PGA2. Inhibition of AA metabolism results in inhibition of growth and Thy 1 expression during thymic organ culture. We report herein that freshly-isolated fetal thymic lobes also have the capacity to metabolize [14C]AA to PGs and HETEs at Days 14 and 16 of prenatal murine development. RNA encoding phospholipase A2, which liberates arachidonic acid from membrane phospholipids, and cyclooxygenase (prostaglandin G/H synthase), the first enzyme involved in the conversion of AA to PGs, are expressed during thymic development. We have localized the cyclooxygenase protein to stromal cells in the fetal and adult thymus. Exogenous AA or an analogue of PGI2 (iloprost) stimulated growth of fetal thymocytes in organ culture. These findings, together with our studies of the morphology of thymic lobes cultured with inhibitors of arachidonate metabolism, support the hypothesis that PGs are required for thymocyte proliferation during thymic development.

Animals↗
PubMed1987

Control of hematopoietic cell growth regulators during mouse fetal development.

Gene expression for the four different growth-regulatory proteins for cells of the myeloid hematopoietic cell lineages was analyzed in mouse fetal and extraembryonic tissues at various stages of development. The macrophage growth inducer MGI-1M (colony-stimulating factor 1) was the only myeloid hematopoietic growth regulator detected as both mRNA and bioactive protein during fetal development. This regulator was produced predominantly in extraembryonic tissues, and the production of hematopoietic growth regulators in embryogenesis was regulated by transcriptional and posttranscriptional controls.

Animals↗
PubMed1992

[Morphological evaluation of fetal development after administration of Poterium sanguisorba for correction of fetoplacental circulation].

Polyphenol preparation of Poterium sanguisorba was tried for the treatment of experimental pregnancy abnormalities. The teratogenic and embryotoxic effects of the preparation administered in a dose of 0.75 LD50 were studied. The therapeutic doses of the drug are characterized by an immunostimulating effect on the mother and help correct the fetoplacental circulation and improve the fetal morphofunctional status.

Animals↗
PubMed1994

Topographical anatomy of the posterior elbow region during fetal development.

We studied the topography of the elbow region with special regard to the ulnar nerve during fetal life. Plastinated 600 microns thick sections through the right and left arms of ten fetuses with a crown-rump length (CRL) of 105 to 360 mm and of a newborn infant were investigated. The ulnar groove does not appear on the dorsal side of the medial humeral epicondyle earlier than at a crown-rump length of 130 mm. It provides the entrance into a formerly described fibro-osseous tunnel called the cubital tunnel. Its floor is formed by the posterior bundle of the ulnar collateral ligament, which bulges medially on flexion of the elbow joint. Up to 270 mm CRL it is composed of rather loosely arranged connective tissue fibres. Later on, its fibres are densely packed and show a parallel orientation. The ulnar nerve is pushed medially but remains behind the medial epicondyle. None of the specimens showed displacement to the anterior site of the elbow joint. An aponeurotic arch bridging the humerus and ulna and covering the ulnar nerve medially could not be identified. The findings in the newborn infant did not reveal any significant differences compared to the fetal specimens.

Elbow Joint↗
PubMed1979

Hemoglobin ontogeny during normal mouse fetal development.

Pure populations of large, nucleated erythrocytes derived from yolk sac blood islands were obtained during normal fetal mouse development. Embryonic hemoglobins were present in these cells early in gestation. Later in gestation, an increasing amount of adults hemoglobin was also synthesized and accumulated in this population of primitive nucleated erythrocytes, as demonstrated by both biochemical and immunocytochemical techniques.

Animals↗