The relationship of 5,5-diphenylhydantoin metabolism to the species-specific induction of gingival hyperplasia in the rat.
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Nowadays we have a whole of drugs, Calcium antagonists (AC), like Verapamil (VE), Nifedipine (NI), Diltiazem (DI), used in cardiovascular therapy. One of them, Nifedipine, has several side effects, out of which is gingival overgrowth. In the present article we present four cases, in which have been analyzed this effect and its resolution in one of them, after drug suppression and patient's hygienic habits correction.
Cyclosporine A selectively inhibits T cell function with minimal effect on humoral immunity. It is largely used with success in kidney transplants. A clinical case of gingival overgrowth secondary to cyclosporine therapy in a 11 year old male who received a kidney transplant is reported. Surgical excision of the excess tissue, light and electron microscopic study are accomplished.
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