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At least 397 records · Page 22Linked to original sources
PubMed1978

Renal infection in the rat after reflux challenge with Pseudomonas aeruginosa.

A rat-pseudomonad reflux model was employed to examine the effect of the size of inoculum on the emergence of renal infection. Widely varying degrees of renal disease observed in challenged animals indicated that a number of variables influenced the outcome of the host-parasite interaction. In this regard, animals in which there was a reduction of the colony counts below a threshold figure rarely gave evidence of renal infection when examined at autopsy on the eighth day following reflux. These results suggest that a threshold level of bacteriuria may also have to be exceeded if renal infection is to become established in patients with vesico-ureteric reflux.

Animals↗
PubMedDate not supplied

[Cystic pyeloureteritis and infection. Presentation forms and review of the literature].

OBJECTIVE: To present three illustrative cases of pyeloureteritis cystica and review the literature. METHODS: Three illustrative cases diagnosed at our department are described. Patient history, clinical features, diagnostic procedures and treatment are analyzed and the literature is reviewed. RESULTS: Our patients had no specific symptoms. All three patients had urinary tract infection with pyeloureteral involvement, which was bilateral in two cases. One of these patients had a long-indwelling catheter. CONCLUSIONS: Pyeloureteritis cystica is a benign and uncommon condition whose etiology is not well-known. It is generally associated with chronic infection and inflammation, and may be difficult to distinguish from other filling defects of the urinary tract. Due to its benign nature, treatment must always be conservative and close follow-up is recommended.

Adult↗
PubMed1979

[Clinical evaluation of cefazedon on patients with urinary tract infections (author's transl)].

The efficacy and tolerance of Cefazedon, a new antibiotic, was investigated clinically on 90 patients with urinary tract infections who also required surgical treatment. Good clinical results were achieved in over 90% of patients after 6 to 7 days of treatment. The bacteriological examination revealed complete elimination of the initially identified pathogens in 89 cases. No difference in treatment results could be established when applying the dose 2 or 3 times daily. On the third day of treatment skin reactions were observed in one case which necessitated discontinuation of treatment. Laboratory blood values as well as control of liver and kidney function before treatment, after and one week past treatment showed no negative influence due to the drug. In approximately 27% a new colonisation mainly with Pseudomonas could not be prevented.

Adult↗
PubMed1975

[Influence of age on risk-factors during pregnancy, delivery and puerperium of primiparae (author's transl)].

The course of pregnancy and delivery of 600 primiparae is being reported. These were divided into four age groups: very young primiparae (14-16 years of age, Group I), older primiparae (35-39 years of age, Group III) and old primiparae (40 years and more, Group IV). These age groups are being compared to a collective of primiparae, by whom the delivery took place at an age between 17 and 34 years (Group II). In these age groups the difference in complication rate during pregnancy, delivery and puerperium is demonstrated. The differences were statistically secured by means of X-2-test. The very young primipara shows the least tendency to delivery complications, still her pregnancy should be considered more risky as compared to Group II, owing to the higher rate of gestosis and the tendency to premature delivery. Groups III and IV show a rising risk rate with increasing age in regard to gestosis (10, 8-30, 8%) and premature delivery (15, 4-28, 6%); also the higher rate of operational delivery was significant (38, 9-44, 6%). The highest risk rate is to be expected in women, who deliver the first time at an age above 40 years. Also the perinatal mortality of newborn is at its highest in this group.

Adolescent↗
PubMed1975

[Clinical experience with ampicillin-cloxacillin (Rectocillin 'Kyowa') in uroloigcal field (author's transl)].

Ampicillin-cloxacillin (Rectocillin 'Kyowa') was administered either orally (capsules) or by intravenous drip infusion to a total of 40 patients and the following results were obtained: 1. Effectiveness obtained in the group received Rectocillin capsules (1,500 mg/day) was 80%. 2. Effectiveness obtained in the group received Rectocillin intravenous drip infusion (3 similar to 10 g/day) was 64.7%. 3. Side effects were encountered in 2 of 40 patients, but none of them were serious, and clinical abnormalities due to this antibiotic were not observed.

Acute Disease↗
PubMedDate not supplied

[The effect of ultra high frequency electromagnetic fields on the intrarenal blood flow and kidney morphology in pyelonephritis (experimental study].

The study was made of the action of electromagnetic decimetric waves (DMW) of mild and strong heat power and placebo on intraorganic circulation using functional polyrheography and morphological examination of the kidneys with infectious-inflammatory process. DMW of the above power have a marked hemodynamic action via stimulation of the circulation of the intermediary zone with an effect of redistribution of the intrarenal blood flow. Weak heat DMW in experimental pyelonephritis exhibit a distinct antiinflammatory effect while strong DMW impact aggravates vascular reaction associated with inflammation. This deteriorates the inflammation and gives rise to hyperimmune reactions. The findings provide pathogenetic grounds for DMW therapy. It is recommended for treatment of patients with chronic pyelonephritis with dynamic obstruction of the upper urinary tracts allowing for the power of the impact and activity of the inflammation.

Animals↗
PubMed1975

Fetal prognosis in obstetric hepatosis.

116 women with obstetric hepatosis gave birth in the years 1971-1972 at the First and Second Departments of Obstetrics and Gynaecology, University Central Hospital, Helsinki. This accounts for a 1.1% incidence of all deliveries at this hospital. During most of these pregnancies fetal well-being was monitored by amnioscopy, by the oxytocin challenge test, by maternal urinary oestriol determinations and by estimating the fetal biparietal diameter weekly. In 38% of these pregnancies, signs of fetal distress were found, mainly an abnormal heart rate, or heart rate pattern, and/or meconium-stained amniotic fluid. These led to increased frequencies of induction of labour and of Caesarean sections performed because of asphyxia or imminent asphyxia as compared with a control group with similar age and parity distribution. There was an increase in the occurrence of twin pregnancies in the hepatosis series (7.6%). There were 4 intrauterine and altogether 8 perinatal losses of 125 infants born to hepatosis mothers. These observations suppport the opinion that there are increased risks for the fetus in pregnancies complicated by obstetric hepatosis. Amnioscopy and fetal heart rate recording during the delivery and oxytocin challenge test were found to be valuable in monitoring the fetal condition. The use of oestriol determinations, at least by employing the method in general clinical practice, was found to be of limited value in the predictive assessment of fetal distress in hepatosis. This might be due to impurities disturbing the determinations or to changed oestrogen metabolism in cholestasis.

Adult↗
PubMed2003

[Pneumopyocystitis in a patient with adult polycystic kidney disease].

OBJECTIVES: We present a case of adult polycystic kidney disease, also known as autosomal dominant polycystic kidney, complicated by infection of the cysts and the formation of gas within them. METHODS/RESULTS: A 59 year old patient diagnosed of adult polycystic kidney disease with chronic renal failure on treatment with haemodialysis, who presented sepsis secondary to infection of the renal cysts. The CT scan demonstrated the presence of gas within the cysts and the microbiology revealed E. coli in one of them. Urgent nephrectomy was performed. A histological specimen of the excised organ is also presented. CONCLUSIONS: Infection of one or more cysts in adult polycystic kidney disease is a rare and serious complication which may require immediate nephrectomy, particularly if gas appears within the cysts.

Diabetes Mellitus, Type 2↗