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Percutaneous transtracheal ventilation for laser endoscopic treatment of laryngeal and subglottic lesions.
Obstructive lesions of the larynx and subglottic space are always a challenging problem for the endoscopist and anaesthetist. At this level, the efficacy and innocuity of a carbon dioxide laser treatment are related to the degree of endoscopic exposure. Thanks to the transtracheal high frequency jet ventilator, it is now possible to assure a free laryngeal endoscopic operative field. The transtracheal catheter is introduced percutaneously through the cricothyroid membrane into the trachea under endoscopic control and connected to a high frequency jet ventilator. From November 1983 to April 1985, this technique has been used in 65 cases. In 12 cases, it was the only alternative to avoid a tracheostomy. The other indications were: laryngeal papillomatosis, resection of T1a cancers of the vocal cords, fibrous strictures secondary to long term intubation, laser arytenoidectomies and benign lesions of the vocal cords. Among many advantages, the following are the most convincing: clear vision of the operative field for the surgeon, complete relaxation of the patient, good respiratory gas exchange, elimination of the risk of ignition of an endotracheal tube by laser, decreased risks of broncho-aspiration of blood and debris, and the facility to provide oxygen and/or mechanical ventilation in the postoperative period. The only complication encountered was a case of cervico-mediastinal emphysema caused by displacement of the tracheal catheter.
Pathology of granulomatous diseases. Histiocytic granulomas.
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Laryngeal scleroma associated with Klebsiella pneumoniae subsp. ozaenae.
Klebsiella pneumoniae subsp. ozaenae was isolated from the pharynx of a woman with laryngeal scleroma. K. pneumoniae subsp. ozaenae is rarely isolated from clinical infections and has never been reported in laryngeal scleroma, which is usually caused by K. pneumoniae subsp. rhinoscleromatis.
Study of the "in vitro" and "in vivo" effects of antibiotics on Klebsiella rhinoscleromatis.
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Electron microscopic study of previously irradiated scleroma.
Nasal biopsies from 2 scleroma patients who had received previous X-ray therapy were investigated under the electron microscope. In the lamina propria, the majority of Mikulicz cells contained numerous small vacuoles. This was attributed to the effect of X-ray therapy causing temporary suppression of the inflammatory process followed by new granuloma formation. The vacuoles of the Mikulicz cells contained some fine granular and fibrillar material of unknown origin. Rounded electron-dense bodies with microprojections on their surface were present near some Mikulicz cells. These structures were considered to be Russell bodies. Occasional small lymph vessels with obstructed lumina were seen. This might indicate the rare spread of Klebsiella rhinoscleromatis bacilli to regional lymph nodes.
Experimental inoculation of Klebsiella rhinoscleromatis bacilli in albino mice.
72 albino mice were intranasally inoculated with Klebsiella rhinoscleromatis suspension with or without the addition of hog mucin. Scleroma-like lesions developed in their lungs more frequently with hog mucin. A liver affection was detected only in 1 animal. K. rhinoscleromatis organisms were recovered from the lung lesions. A possible potentiating effect of hog mucin is discussed.
SCLEROMA: AN ETIOLOGICAL STUDY.
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Scleroma in Guatemala, with a study of the disease based on the experience of 108 cases.
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Scleroma. Klebsiella rhinoscleromatis and its effect on mice.
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Ultrastructure of nasal scleroma (emphasizing the fine structure of Klebsiella rhinoscleromatis within the lesion).
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Scleroma with intracranial extension.
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Endoscopy of the air passages with special reference to scleroma.
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Scleroma affecting the middle ear cavity with report of three cases.
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Palatal presentation of scleroma.
A case with palatal presentation of scleroma is presented due to its rarity and unusual manifestations. The patient presented with only palatal symptoms. Nasal endoscopy revealed signs of all three stages of scleroma: catarrhal, granulomatous and sclerotic stages. Histopathology was vital in the diagnosis. The patient was treated by medical therapy, and palatal symptoms were relieved by uvulopalatopharyngoplasty.
Scleroma; observations on seven cases in one family for 10 years and another case which developed intracranial complications after five years.
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