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PubMed1976

Four- and six-month-old infants' visual responses to joy, anger, and neutral expressions.

24 infants, 12 4-month-olds and 12 6-month-olds, were repeatedly shown slides of 3 facial expressions. The expressions were previously judged by obervers to be indicators of joy, anger, and no emotion, respectively. The duration of the first visual fixation to each presentation of the slides was monitored for each subject. The data indicated that the infants looked at the joy expression significantly more than at either the anger or neutral expressions. The results suggest that infants are capable of discriminating emotion expressions earlier in their development than previous studies have implied.

Anger↗

PubMed2000

Impulsiveness and the prolactin response to d-fenfluramine.

RATIONALE: A number of studies have reported abnormalities of serotonin function in aggressive and impulsive behaviours in psychiatric and forensic populations. It is unknown whether this is because serotonin function plays a part in determining the dimension of trait impulsiveness in the general population or whether this is restricted to these behaviourally extreme groups. METHOD: The prolactin response to d-fenfluramine was measured in subjects scoring high and low on a scale of impulsiveness selected from a panel of healthy volunteers screened for impulsiveness. Measures included the 17 impulsiveness scale, State Trait Anger Expression Inventory (STAngXI) and the Tridimensional Personality Questionnaire (TPQ). Plasma cortisol was also determined along with fenfluramine and its metabolite norfenfluramine. RESULTS: The high impulsive group had reduced AUC (PRL) compared with the low impulsive group; this remained significant after adjusting for baseline prolactin, cortisol and drug levels. There was no significant association between impulsiveness, the harm avoidance subscale of the TPQ or trait anger (STAngXI) and prolactin rise. Repeated serum prolactin measures were not significantly different between the two groups. CONCLUSIONS: This study provides some support to the hypothesis that reduced serotonin function contributes to high trait impulsiveness and is not restricted to behaviourally extreme populations.

Adult↗

PubMed2003

Interaction of prime and target in the subliminal affective priming effect.

It has been found that an emotional stimulus such as a facial expression presented subliminally can affect subsequent information processing and behavior, usually by shifting evaluation of a subsequent stimulus to a valence congruent with the previous stimulus. This phenomenon is called subliminal affective priming. The present study was conducted to replicate and expand previous findings by investigating interaction of primes and targets in the affective priming effect. Two conditions were used. Prime (subliminal presentation 35 msec.) of an angry face of a woman and a No Prime control condition. Just after presentation of the prime, an ambiguous angry face or an emotionally neutral face was presented above the threshold of awareness (500 msec.). 12 female undergraduate women judged categories of facial expressions (Anger, Neutral, or Happiness) for the target faces. Analysis indicated that the Anger primes significantly facilitated judgment of anger for the ambiguous angry faces; however, the priming effect of the Anger primes was not observed for neutral faces. Consequently, the present finding suggested that a subliminal affective priming effect should be more prominent when affective valence of primes and targets is congruent.

Adult↗

PubMed2000

Long-term assessment of psychological well-being in a randomized placebo-controlled trial of cholesterol reduction with pravastatin. The LIPID Study Investigators.

BACKGROUND: There is controversial evidence that a low serum cholesterol level is associated with an increased risk of depression, suicide, and violence. The aim of this study was to identify or exclude any small or infrequent adverse effect of long-term reduction of serum cholesterol with pravastatin sodium on psychological well-being. METHODS: The study population consisted of 1130 respondents from a representative sample of 1222 patients with stable coronary artery disease participating in the Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) study. Subjects were randomized in a double-blind manner to treatment with pravastatin sodium, 40 mg/d (n = 559), or placebo (n = 571) for at least 4 years. Psychological well-being was assessed with a standard self-administered questionnaire at baseline and after 6 months, 1 year, 2 years, and 4 years. The questionnaire assessed anxiety and depression, anger, impulsiveness, alcohol consumption, and adverse life events. RESULTS: Serum cholesterol levels decreased by an average of 1.3 mmol/L (50 mg/dL) with pravastatin therapy and did not change with placebo. During follow-up there was no significant difference by treatment group in measures of anxiety and depression, anger expression, or impulsiveness (95% confidence interval excluded differences of >0.2 SD) and no difference in the proportion of subjects with excessive alcohol consumption or adverse life events (odds ratio, 1.0; 95% confidence interval, 0.8-1.2). There was no evidence of a treatment effect for persons whose baseline serum cholesterol level was in the lowest 10% (<4.6 mmol/L [178 mg/dL]) or whose scores for anxiety and depression, anger, or impulsiveness were in the highest 10% at baseline. There was no association between change in the serum cholesterol level and measures of anxiety and depression, anger, or impulsiveness during follow-up. CONCLUSION: Long-term reduction of serum cholesterol with pravastatin has no adverse effect on psychological well-being.

Adult↗

PubMed2005

Impaired decision making in suicide attempters.

OBJECTIVE: The understanding of suicidal behavior is incomplete. The stress-diathesis model suggests that a deficit in serotonergic projections to the orbitofrontal cortex is involved in susceptibility to suicidal behavior. The orbitofrontal cortex has been implicated in decision making, a cognitive function dealing with complex choices that may be under serotonergic modulation. In this preliminary study, the authors assessed decision making in suicide attempters. METHOD: The authors used the Iowa Gambling Task to investigate patients with a history of violent (N=32) or nonviolent (N=37) suicidal behavior, patients suffering from affective disorders with no history of suicidal behavior (N=25), and healthy comparison subjects (N=82). Patients were assessed when they were not suffering from a current axis I disorder. The authors also assessed the correlation of Iowa Gambling Task performance with psychometric measures of impulsivity, hostility, anger, aggression, and emotional instability. RESULTS: Both groups of suicide attempters scored significantly lower than healthy comparison subjects, and violent suicide attempters performed significantly worse than affective comparison subjects. No significant differences were observed between the groups of suicide attempters or between the two comparison groups. The differences in performance could not be accounted for by age, intellectual ability, educational level, number of suicide attempts, age at first suicide attempt, history of axis I disorder, or medication use. Iowa Gambling Task performances were correlated positively with affective lability and with anger expression but not with impulsivity. CONCLUSIONS: Impaired decision making, possibly due to emotional dysfunction, may be a neuropsychological risk factor for suicidal behavior.

Adult↗

PubMed1991

Psychosocial factors in chronic spinal cord injury pain.

Chronic pain is a problem among patients with spinal cord injuries, but the psychosocial factors associated with spinal cord injury (SCI) pain are not well understood. To understand SCI pain further, 54 patients (19 with quadriplegia and 35 with paraplegia) completed the Beck Depression Inventory, State-Trait Anxiety Inventory, Profile of Mood States, Acceptance of Disability Scale and SCI Interference Scale. Forty-two patients stated they had SCI pain and completed the Multidimensional Pain Inventory and the Pain Experience Scale. Results revealed that anger and negative cognitions were associated with greater pain severity. Patients who reported pain in response to a general prompt experienced more severe pain than patients who reported pain only when directly questioned about the presence of pain, but these different reporting groups did not differ on emotional variables. Those who were less accepting of their disability reported greater pain severity. Additionally, patients who perceived a significant other expressing punishing responses (e.g., expressing anger at the patients or ignoring the patients) to their pain behaviors reported more severe pain. Level of lesion, completeness of injury, surgical fusion and/or instrumentation and veteran status were not associated with pain severity. Finally, pain was associated with emotional distress over and above the distress associated with the SCI itself. Overall, psychosocial factors, not physiological factors, were most closely associated with the experience of pain. Multidimensional aspects of pain are used to explain these findings and suggest that treatment should be directed at the emotional and cognitive sequelae of chronic SCI pain.

Adult↗

PubMed1992

Psychobiologic responses to exercise at different times of day.

The primary purpose of this investigation was to determine whether selected psychobiologic responses to running exercise vary as a function of the time of day at which exercise is performed. Twelve adult males completed four bouts of randomly assigned, submaximal exercise (20-min runs at 70% VO2max) at 0800, 1200, 1600 and 2000 h. Since selected personality traits have previously been shown to influence circadian rhythms, personality assessments (i.e., Eysenck Personality Questionnaire, EPQ; Morningness-Eveningness Questionnaire, MEQ; Spielberger's State-Trait Anger Expression Inventory, STAIX; and State-Trait Anxiety Inventory, STAI) were made during the initial testing session. The group studied scored within the normal range on the traits assessed by the EPQ, STAIX, and STAI. Also, subjects were not able to be classified as either "morning" or "evening" types based on MEQ scores. Ten minutes before as well as 10 and 20 min following the exercise bouts, state anxiety, state anger, blood pressure, and heart rate were assessed. Multivariate ANOVAs (four time of day conditions x three trials) revealed significant main effects for the trial factor for state anxiety, state anger, heart rate, and systolic blood pressure. State anxiety, state anger, and systolic blood pressure were found to be reduced at both the 10 and 20 min post-exercise assessment periods when compared with pre-exercise levels. ANOVAs performed on the difference scores showed that the mood improvements and cardiovascular changes were independent of the time of day that exercise was performed, and these findings were confirmed by ANCOVAs, which adjusted for differences in initial values across the four time of day conditions.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

PubMed2006

Baseline psychosocial predictors of survival in localised breast cancer.

Despite the large number of studies on the impact of psychosocial factors on breast cancer progression, there is no certainty about the contributing factors or processes involved. We investigated the relative impacts of socioeconomic, psychological, and psychosocial factors on survival in breast cancer. A consecutive sample of 102 patients (participation 82%) under 72 years of age with locoregional breast cancer completed validated questionnaires on coping with cancer, emotional expression (anger), perceived available support, noncancer life stresses, and quality of life 3-4 months after diagnosis. Survival times were measured from the date of diagnosis to the date of relapse and further to the date of death or date of last follow-up. Cumulative Cox regression analyses were carried out. After controlling for biological prognostic factors, age, and baseline treatment, longer survival was predicted by a long education and a minimising-related coping, while shorter survival was predicted by emotional defensiveness (antiemotionality), behavioural-escape coping, and a high level of perceived support. A shorter event-free time was also predicted by unemployment and depressive symptoms. Cancer survival is affected by a complex combination of psychosocial factors, among which minimising predicts a favourable prognosis and anger nonexpression and escape behaviour an unfavourable prognosis. Higher socioeconomic status is associated with longer survival. High scores in well-being scales may reflect emotional nonexpression.

Adaptation, Psychological↗

PubMed2002

Efficacy of citalopram in anorexia nervosa: a pilot study.

INTRODUCTION: Anorexia nervosa (AN) still lacks a defined treatment. Since fluoxetine proved effective in weight-restored anorexics, this pilot study evaluates the efficacy of another SSRI, citalopram, in restricting-type AN. EXPERIMENTAL PROCEDURES: Fifty-two female anorectic outpatients were randomized in the citalopram (n=26) and waiting list (n=26) as a control group. Efficacy was assessed using Eating Disorder Inventory-2, Eating Disorder Inventory-Symptom Checklist, State-Trait Anger Expression Inventory, Beck Depression Inventory, Symptom Checklist-90 and Structured Clinical Interview for DSM-IV Axis II Disorders. RESULTS: Thirteen patients dropped-out, thus 19 patients received citalopram and 20 remained in the control group. After 3 months of treatment, the citalopram group showed a decrease on BDI and SCL-90 Depression subscale and an improvement of baseline obsessive compulsive features on SCL-90, EDI-2 impulsiveness and Trait-anger on STAXI. Weight gain was similar in the two groups. DISCUSSION: These preliminary results support the efficacy of citalopram in anorectics. Citalopram seems to improve depression, obsessive-compulsive symptoms, impulsiveness and Trait-anger.

Adolescent↗

PubMedDate not supplied

Dropout from brief psychotherapy within a combination treatment in bulimia nervosa: role of personality and anger.

BACKGROUND: To explore the personality, psychopathology, and clinical features of bulimic patients who do not complete psychotherapy, within a combined treatment. METHODS: 86 patients with bulimia nervosa (BN; DSM-IV) were evaluated before beginning treatment. The Eating Disorder Inventory II (EDI-II), State-Trait Anger Expression Inventory (STAXI), and the Temperament and Character Inventory (TCI) were administered to all patients. RESULTS: 3 subjects failed to engage in psychotherapy. Comparing patients who dropped out (n = 28) with those who did not drop out from psychotherapy (n = 55), significant differences were found in some psychopathologic (EDI-II, STAXI) and personality (TCI) variables. In particular, patients who dropped out from the treatment were more impulsive and more likely to feel anger; they were also less cooperative and less self-directive. No significant differences in sociodemographic, clinical variables and in response to fluoxetine were found between the two groups (dropout and completers). CONCLUSIONS: We found a characteristic profile in the bulimic patients who dropped out from brief psychotherapy, i.e., they are less cooperative and more predisposed to anger. These data suggest that dropping out in a subgroup of BN patients could be related to borderline personality traits and to difficulties in making and maintaining a therapeutic relationship. Implications for treatment are discussed.

Adult↗

PubMed2004

Racism and hypertension among African Americans.

The purpose of this study was to examine the relationship of racism and blood pressure (BP). Participants were 162 urban African American adults. Measurements included the Racism and Life Experiences Scale, Krieger Racial Discrimination Questionnaire, State-Trait Personality Inventory (anxiety and depression), State-Trait Anger Expression Inventory, and automated measures of BP. Correlational and multiple regression analyses were done to examine relationships among key variables, t tests and ANOVA tested group differences by age, gender, and racism category. There was a high prevalence of perceived racism, which was not associated with higher BP. The racism/BP relationship was moderated by age with significant age related differences noted. Older participants (40 years or older) experienced more distress from racism, more anger suppression, and higher BP but lower levels of stress emotions. The highest levels of BP were noted in older adults reporting the lowest level of perceived racism, raising the issue of "internalized oppression."

Adaptation, Psychological↗

PubMed1989

Hostility patterns and cardiovascular reactivity to stress.

Sixty male subjects performed two challenging tasks while systolic blood pressure, diastolic blood pressure, and heart rate were monitored. They also completed the Cook and Medley Hostility Scale and measures of social support and mode of anger expression. Subgroups of subjects who differed in the patterns of their responses to the hostility items were identified via cluster analytic techniques. Exaggerated reactivity in systolic blood pressure to the two experimental tasks was exhibited by subjects in a subgroup who appear to have negative feelings toward people, but disavow these feelings and inhibit aggression so as not to alienate others. However, these individuals may have difficulty concealing their view of others and controlling their anger which, in turn, may erode their social support.

Adult↗

PubMed1998

Dimensions of anger and CHD in men and women: self-ratings versus spouse ratings.

One hundred one males and 95 females referred for thallium stress testing were administered Spielberger's State-Trait Anger Expression Inventory (STAXI), the Ho scale cynicism items, the Cynical Beliefs Scale, and Bendig's Manifest Anxiety Scale. A subset of 53 males and 43 females was rated by their spouses by means of STAXI. Based on the thallium findings and their medical history, patients were classified either as healthy, or as having documented CHD, or as questionable. Patients' STAXI and cynicism measures were submitted to a principal-components analysis which yielded three factors: Impulsive Anger-out. Inwardly experienced anger, and Cynicism. The relationships between factor scores and documented CHD was determined by means of logistic regression analyses. Only Impulsive Anger-out correlated (positively) with CHD, but only when based on spouses' ratings and only in males (p < .01, RR = 3.13). Covarying traditional risk factors and cynicism did not attenuate this relationship. However, a significant relationship between Ho scale cynicism and CHD did not survive adjustment for traditional risk factors. Anxiety was not a risk factor for CHD.

Adult↗

PubMedDate not supplied

Psychological traits and emotion-triggering of ICD shock-terminated arrhythmias.

OBJECTIVE: We have previously reported on the triggering of arrhythmia and hence, implanted cardioverter-defibrillators (ICD) shock by strong emotion. The purpose of the present study was to examine whether concordant psychological traits distinguish patients who experience emotion-triggered ICD shock. METHODS: Two hundred forty ICD patients completed the Speilberger Trait Anxiety and Anger Inventories and Anger Expression Scale, and the abridged Cook-Medley Hostility Scale approximately 2 months after ICD implantation. Patients were also given a structured diary to record mood states retrospectively for the period 0 to 15 minutes preceding ICD shock and for a period corresponding to the same time of day 1 week later. Patients who reported emotion-triggered ICD shock were compared on concordant psychological measures to patients who did not. RESULTS: Patients who reported at least moderate anger in the 0 to 15 minutes before ICD shock scored significantly higher on Speilberger Trait Anger (24.18 +/- 3.97 vs. 17.04 +/- 2.17, p < .0001), and Cook-Medley Aggressive Responding (5.76 +/- 0.75 vs. 3.96 +/- 1.30, p < .0001) and Hostile Affect (3.59 +/- 0.80 vs. 2.04 +/- 1.02, p < .0001), and lower on Speilberger Anger Control (7.94 +/- 1.43 vs. 10.64 +/- 1.19, p < .001) than those who did not. In multivariate analysis, only Trait Anger remained a significant predictor of anger-triggered shock (chi2 = 7.10, p < .008). Patients who reported at least moderate anxiety in the 0 to 15 minutes before ICD shock scored significantly higher on Speilberger Anxiety (22.43 +/- 1.65 vs. 19.96 +/- 1.71, p < .0001) than those who did not. CONCLUSION: Stable psychological factors are associated with risk for ICD-shock triggered by concordant strong emotion.

Aged↗

PubMed1988

Construct validity of the Toronto Alexithymia Scale.

Previous reports have documented the development of the Toronto Alexithymia Scale (TAS) in addition to evaluating its reliability and validity. The present paper describes two studies designed to further evaluate the construct validity of the TAS. In Study I 117 university students completed the TAS and the three subscales of the Short Imaginal Processes Inventory. In Study II 74 students completed the TAS and measures of ego strength, anger expression, and physical symptoms. In both studies the pattern of correlations between the TAS and the various psychological measures converged and diverged in a theoretically meaningful fashion, providing further evidence for the validity of the TAS and of the alexithymia construct.

Adolescent↗

PubMed2006

Relationship of alexithymia to cardiovascular disease risk factors among African Americans.

BACKGROUND: Alexithymia, a deficit in emotional awareness and expression, may contribute to cardiovascular disease (CVD) and other diseases. African Americans have a high prevalence of CVD, but almost nothing is known about alexithymia in this ethnic group. This study examined the relationship of alexithymia to a range of risk factors for CVD among African Americans. METHODS: On a community sample of 162 African American adults, we assessed alexithymia (Toronto Alexithymia Scale-20) and several risk factor domains: physiological (body mass index, blood pressure), behavioral (smoking, exercise), emotional (trait anxiety, depression, and anger; forms of anger expression), racial discriminatory, and socioeconomic (income, education). RESULTS: Alexithymia was positively correlated with all emotional risk factors (P < .01) and inversely correlated with socioeconomic status (P < .01). Alexithymia has a small, inverse relationship with responses to racism (P < .01) but was not significantly related to the experience of racism. Alexithymia was weakly related to smoking but was unrelated to physiological risk factors. These relationships were largely unchanged when only people without hypertension (n = 116) were studied. CONCLUSIONS: This pattern of relationships is consistent with findings on ethnic majority samples and suggests that alexithymia as measured with the Toronto Alexithymia Scale-20 is a valid construct among African Americans. It correlates with socioeconomic and emotional variables in this population, but only minimally or not at all with behavioral or physiological factors. If alexithymia influences CVD and other diseases, it appears to do so through social and emotional pathways.

Adolescent↗

PubMed2006

Anger- and aggression-related traits are associated with polymorphisms in the 5-HT-2A gene.

BACKGROUND: This study investigates the association of four single nucleotide polymorphisms (SNPs) in the serotonin 2A (5-HT-2A) receptor gene with anger-, aggression- and suicide-related behavior in a total of 566 subjects (203 German suicide attempters and 363 German community-based healthy volunteers). METHODS: Anger- and aggression-related traits were assessed by using the State Trait Anger Expression Inventory (STAXI) and the Questionnaire for Measuring Factors of Aggression (FAF). RESULTS: Three (rs643627-rs594242-rs6311: A-C-T), two (rs594242-rs6311: C-T) and a single functional (rs6311: T) marker were protective against suicidal behavior. The complementary makers (rs594242-rs6311: G-C and rs6311: C) were associated with increased risk for non-violent (p=0.01; p=0.009 respectively) and impulsive suicidal behavior (p=0.03; p=0.01 respectively). Furthermore, CC-homozygotes for the functional SNP rs6311 reported more anger- (p=0.004) and aggression-related behavior (p=0.011). CONCLUSION: We conclude that variations in the 5-HT-2A gene may modify the phenotype of suicide-, anger-, and aggression-related behavior. Further studies should especially focus on intermediate personality traits in this context.

Adolescent↗

PubMed1998

Serum lipid concentrations, hostility and cardiovascular reactions to mental stress.

The objective of the present study was to determine whether serum lipid concentrations interact with hostility to affect cardiovascular responses to mental stress. One-hundred and seventy-four male subjects were screened with the Cook and Medley hostility scale (Ho), the anger expression inventory by Spielberger and a general health questionnaire. Subjects in the upper (n = 22) and lower (n = 22) quartile of the Ho score distribution were asked to take part in a laboratory experiment. Continuous measures of heart rate, blood pressure, respiration and electrodermal activity were taken while participants carried out a series of behavioral maneuvres, including mental arithmetic and mirror star tracing. Prior to the experiment fasting blood samples were taken for lipid determinations. The results show higher heart rate reactivity in high hostile than low hostile subjects. High hostile subjects also reported more anger and frustration in response to tasks. Hostility groups differed in lipid levels in that high hostiles had higher triglyceride and VLDL-c concentrations than low hostiles. Cholesterol levels showed an inverse association with cardiovascular reactivity but only in low hostile subjects. No such associations could be found in high hostiles. We conclude that there is partial support for both, the hyperreactivity and the health behavior model linking hostility and cardiovascular disorder.

Adult↗