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PubMedDate not supplied

Distance between patients' subjective perceptions and objectively evaluated disease severity in chronic heart failure.

BACKGROUND: Chronic heart failure (CHF) is a socially relevant condition carrying an adverse prognosis. Systematic analysis is needed of the relationship between quality of life (QoL) - what patients are most interested in - and objective parameters of CHF severity - which largely determines physicians' care. METHODS: We prospectively investigated QoL, as ascertained by the Minnesota Living with Heart Failure Questionnaire, alongside all the currently used objective clinical/instrumental (electrocardiographic, echocardiographic, hemodynamic and functional capacity) indicators of disease severity in 106 consecutive CHF patients. RESULTS: Besides persistence of sinus rhythm (p = 0.007), the only objective parameters that correlated with QoL were NYHA class (p < 0.001) and distance covered during the six minutes walking test (p < 0.001) (two indications of patients' ability to attend to their daily needs). Presence of left bundle branch block was associated with a worse QoL only in patients with CHF due to ischemic heart disease (p = 0.032). All the other clinical/instrumental parameters showed no relation with QoL (p > 0.150 in all cases). CONCLUSIONS: Objective indicators of disease severity, which largely determine physicians' care, appear to have little bearing on QoL, suggesting that current treatment for CHF fails to satisfy patients' perceived needs. The possibility of cost-effective nonpharmaceutical therapeutic protocols (e.g. psychological interventions) specifically designed to improve patients' QoL deserves investigation as a much needed new approach to the management of CHF.

Activities of Daily Living↗

PubMed1996

Stereoscopic depth constancy depends on the subject's task.

Under identical viewing conditions, observers made two types of judgement about the shape of stereoscopically defined surfaces: one required an estimate of viewing distance for correct performance (e.g. setting the depth of a hemi-cylinder to equal its half-height or a dihedral angle to 90 deg), the other did not (matching the depth of, for example, sinusoidal corrugations or hemi-cylinders presented at two distances). Depth constancy for the two types of task was about 75% and 100%, respectively. We argue that observers may use a simple "direct" strategy to perform the depth matching task rather than constructing and comparing a metric representation of each surface.

Convergence, Ocular↗

PubMed2005

Focus cues affect perceived depth.

Depth information from focus cues--accommodation and the gradient of retinal blur--is typically incorrect in three-dimensional (3-D) displays because the light comes from a planar display surface. If the visual system incorporates information from focus cues into its calculation of 3-D scene parameters, this could cause distortions in perceived depth even when the 2-D retinal images are geometrically correct. In Experiment 1 we measured the direct contribution of focus cues to perceived slant by varying independently the physical slant of the display surface and the slant of a simulated surface specified by binocular disparity (binocular viewing) or perspective/texture (monocular viewing). In the binocular condition, slant estimates were unaffected by display slant. In the monocular condition, display slant had a systematic effect on slant estimates. Estimates were consistent with a weighted average of slant from focus cues and slant from disparity/texture, where the cue weights are determined by the reliability of each cue. In Experiment 2, we examined whether focus cues also have an indirect effect on perceived slant via the distance estimate used in disparity scaling. We varied independently the simulated distance and the focal distance to a disparity-defined 3-D stimulus. Perceived slant was systematically affected by changes in focal distance. Accordingly, depth constancy (with respect to simulated distance) was significantly reduced when focal distance was held constant compared to when it varied appropriately with the simulated distance to the stimulus. The results of both experiments show that focus cues can contribute to estimates of 3-D scene parameters. Inappropriate focus cues in typical 3-D displays may therefore contribute to distortions in perceived space.

Accommodation, Ocular↗

PubMed2001

Effect of geometric field of view on stereoscopic spatial judgments.

Within a stereoscopic display the field of view (FOV) was held constant at 13.86 degrees while the geometric field of view (GFOV) was varied across four levels: 0 degrees (parallel), 13.86 degrees (veridical), 50 degrees and 100 degrees. Participants performed a distance-matching task where they adjusted the distance of a standard track from the centre of the display to match the distance of a target track from the same point. The results indicated that while the least error occurred in the veridical GFOV condition, small variations of GFOV away from the veridical have little effect. Large differences between FOV and GFOV (36 degrees and 86 degrees) increased errors markedly. A trend toward better performance in the veridical GFOV condition relative to the parallel GFOV condition suggests that the use of linear perspective information in a stereoscopic display may facilitate more accurate spatial perception. Actual or potential applications of this work include stereoscopic display design in aviation and non-aviation settings.

Adult↗

PubMed1964

DISTANCE PRECEPTION IN DARKNESS.

Human subjects viewed round stimuli located equidistantly in the horizontal and vertical planes of vision under conditions where presumed cues to size were present and where they were systematically eliminated. Two experiments revealed a consistent tendency for the horizon object to be judged the closer. Cues introduced reduced the effect.

Biomedical Research↗

PubMed1984

Distance estimation in the Mongolian gerbil: the role of dynamic depth cues.

The role of dynamic depth cues in distance estimation was investigated in the Mongolian gerbil. Animals were trained to jump randomly varied distances on a jumping stand under both binocular and monocular conditions. Videotape analysis revealed that prior to jumping, the gerbils executed a series of vertical head movements, the amplitude and velocity of which were related to the gap distance and to each animal's accuracy. This suggested that the gerbils were employing motion parallax cues to judge distance. An inverse relation between the magnitude of forward movement and the frequency of vertical head movements suggested that loom cues were also being used to judge distance. This hypothesis received support from a second experiment in which forward movements were constrained by a short take-off platform. In this condition, frequency of vertical head movements increased, suggesting that a compensation had occurred for the loss of information from loom.

Animals↗

PubMed1980

Effects of posthypnotic suggestion on perceived egocentric distance.

The effects of posthypnotic suggestion on the perception of egocentric distance were evaluated by two methods, one direct and the other indirect. The direct method was the verbal report of the perceived distance of the stimulus. The indirect method used a measure based on apparent concomitant motion of the stimulus with a lateral movement of the head. The indirect method, unlike the direct method, has been shown to be insensitive to cognitive biases. Two highly trained hypnotic observers received posthypnotic suggestions to see a point of light at approximately 2, 4, or 6 ft (61, 122, or 183 cm) from themselves. For each suggested distance the light was physically at 2, 4, or 6 ft. As a control, trails were completed using these same physical distances without the posthypnotic suggestions. Nine experimental trails, one for each combination of suggested distance and physical distance, constituted a trial set. One observer completed three sets, and the other completed two sets. It was found that the posthypnotic suggestions affected the direct but not the indirect measures of the perceived distances of the light.

Adolescent↗

PubMed2002

Stereoacuity at distance and near.

PURPOSE: Because previous studies have reported conflicting evidence, we examined a possible difference in stereoacuity between distance and near, in particular using a random-dot display. We compared distance and near stereoacuities using identical presentation formats at the two distances. METHODS: Twelve young adults with low, stable refractive errors and apparently normal binocular vision participated. Stereoacuity was determined with a Mentor B-VAT II using Random Dot E (BVRDE) and Contour Circles (BVC) stereograms presented on a standard monitor (25 x 19.3 cm) at 518 cm (distance-habitual) and a small monitor (2.0 x 1.4 cm) at 40 cm (near-habitual). To examine whether accommodation-convergence influenced stereoacuity, testing at 40 cm was repeated with the addition of +2.50 DS lenses and base-in prisms (near-compensated) that created the same accommodation and convergence demands as for distance-habitual viewing. RESULTS: The two stereotests produced similar findings. Stereoacuity was not significantly different for distance-habitual and near-habitual viewing of the BVRDE (p = 0.43) and BVC (p = 0.79) stereotests. Near-compensated stereoacuity was worse than near-habitual (BVRDE, p = 0.005; BVC, p = 0.004) and distance-habitual (BVRDE, p = 0.05; BVC, p = 0.003) for both stereotests. Because near stereoacuity with yoked prisms (control condition) was the same as without prism (near-habitual), prism-induced optical distortions cannot account for the difference. CONCLUSIONS: Stereoacuity was not different at distance and near under normal viewing conditions. The conflict between subject knowledge of target proximity and the optically-induced relaxation of accommodation and convergence, or an inaccurate accommodative-convergence response, might have caused poor near-compensated stereoacuity.

Accommodation, Ocular↗

PubMed1993

[The Freiburg Stereotest. On assessment of stereovision in automobile driver examination].

BACKGROUND: The "Freiburg Stereotest" is a new instrument where disparate pictures are generated by a computer and displayed on one single high resolution video monitor. In the present work, the Freiburg Stereotest was used to check the stereo qualification for certain categories of driver's licence. For this purpose, a determination of the smallest detectable disparity is not reasonable. Rather, it should be checked whether or not a certain disparity, usually well above threshold, is recognized with a sufficient reliability. We have chosen a disparity of 100 arcsec; this value is considered to be an acceptable requirement for certain categories of driver's licence. SUBJECTS AND METHODS: 6 strabismic subjects were examined binocularly and 10 normal subjects were examined both binocularly and monocularly. Two targets ("busses"), side by side and different in depth by a disparity of 100 arcsec, were presented 78 times and, in a two-alternative forced-choice procedure, a minimum of 66 hits was required to pass the test. Monocular cues were excluded by a systematic variation of the lateral distance between the two targets. RESULTS: The strabismic subjects and the monocularly occluded normal subjects reached random scores only. With both eyes open, 8 of the 10 normal subjects reached scores near 100%, while 2 of them passed the test only when the lateral distance between the two targets was 15 minarc or less. For a lateral distance between the two targets of more than 15 minarc, these 2 subjects showed a learning effect. CONCLUSIONS: The Freiburg Stereotest allows to determine with statistical significance whether or not a proband can recognize a certain disparity which may be required for a driver's licence.

Adult↗

PubMed1994

Size constancy, depth constancy and vertical disparities: a further quantitative interpretation.

The size and depth constancies considered here operate only at near distances (< about 2 m) in a static stimulus situation with vergence as the only cue to distance. The innervation of the extraocular muscles, as evidenced by the corollary discharge, provides information about the vergence of the eyes and hence about the egocentric distance both for symmetrical and asymmetrical vergences. Size and depth constancies are regarded as the first and second stages of a linked two-stage process. In the lateral geniculate nuclei compensatory adjustments are separately applied to each retinal image as they are received from the two eyes. The modified ocular images, with their associated vertical and horizontal disparities, now provide synaptic inputs to binocularly activated cells in the visual cortex. Then, by a process akin to the induced effect, cortical cells with geniculate afferents with vertical disparities will have their outputs expressed in terms of horizontal disparities. The horizontal disparity outputs of these cortical cells are then further multiplied by the outputs from cortical cells with geniculate afferents with horizontal disparities. It is this second multiplicative process that brings about the quadratic relationship between horizontal retinal disparity and egocentric distance. The proposed mechanisms involve the known ability of the visual system to detect and respond to vertical as well as horizontal disparities and provide a definite role for the induced effect in the perceptual process. The above neural model is based on fairly simple equations that give a remarkably adequate description of the operation of the two constancies.

Cybernetics↗

PubMed1995

On the focal distance of the eye during sighting in pistol shooting.

We measured the focal distance and pupil diameter on the eyes of 11 marksmen sighting a pistol target at 23 m distance. Both upon the focal distance and pupil diameter of the subjects, we estimated the point at which they were looking during sighting. Calculation based on depth of field which can be divided from the pupil diameter of 4.5 mm suggested that the subjects were looking at the foresight of the pistol approximately 80 cm in front of the eye during sighting.

Adult↗

PubMed1993

Effects of target distance and pupil size on letter contrast sensitivity with simultaneous vision bifocal contact lenses.

Using simulated presbyopia we measured the effects of target vergence and pupil size on letter contrast sensitivity while subjects wore accurately centered simultaneous vision bifocal contact lenses. These experiments examined the increase in depth of focus provided by two bifocal contact lenses, and the effects of pupil size on near and distance vision. Monocular contrast sensitivity was assessed with three different designs of soft contact lenses. First, as a single vision control, we measured contrast sensitivity with a Bausch & Lomb, Optima 38 lens corrected for distance. We then measured contrast sensitivity with an Allergan Optical, Hydron Echelon, which is a diffractive simultaneous bifocal and a CIBA Vision, Spectrum, which is a concentric design, center-near, two-zone simultaneous vision bifocal. In general both bifocal contact lenses improved contrast sensitivity at near but decreased contrast sensitivity at distance (when compared to the single vision lens). With a fixed 3.5-mm artificial pupil, the Echelon lens had two clear peaks of sensitivity, one at distance (0.00 D) and one at near (-2.00 D), but the Spectrum lens had no clear peaks. Performance of the Spectrum lens depended on its center zone size. Near (-2.00 D) and distance (0.00 D) contrast sensitivity was measured with pupil sizes that ranged from 1 to 6 mm. The results showed that visual performance with a diffractive lens was almost independent of pupil diameter up to 3 to 4 mm but, as predicted, performance with the two-zone lens depended critically on pupil size.

Contact Lenses, Hydrophilic↗

PubMed1978

Development of sensitivity to information provided by cast shadows in pictures.

The shadow cast by an object in a two-dimensional picture can specify for the observer the spatial relations between that object and its surroundings, and also the shape and size of the object itself. Some sensitivity to this information is present even in three-year-old children. Experiment 1 provided evidence that three- and four-year-old children can rely on the shape of the shadow cast by an object to judge the shape of the object. In experiment 2, with adults and three- and four-year-old children, the location of the shadow cast by an object influenced the perceived depth and height off the ground plane of the object. Although even the three-year-old children were sensitive to the location of the cast shadows, there was evidence of improvement with age in judging the distance and size of the object. The three-year-olds were not able to judge the object's size when the location of the cast shadow provided the only differential information for size. In contrast, they were significantly better in judging size when the location of the object, rather than the location of the shadow, was varied.

Adult↗

PubMed2002

Scale invariance in near space: pointing under influence of context.

This paper describes the results of a pointing task close to the observer. Unlike most research reported in literature, the stimuli were composed of real solid objects in an unambiguous context, free of any cue conflict. Moreover, the stimuli were either within arm-reach or just beyond arm-reach, thus having strong binocular depth cues. Surprisingly, systematic errors up to four times the standard deviation were found. These errors depended mainly on the variations in context and hardly on egocentric distance. In good first approximation, the results were scale invariant. These results are in direct conflict with classic theories about visual space. The stimuli were unambiguous real 3-D equivalents of the computer-generated stimuli we used in a previous experiment. A comparison of the results did not reveal a clear effect of a depth cue conflict between accommodation and disparity.

Adolescent↗

PubMed1990

Adaptation to optically-increased interocular separation under naturalistic viewing conditions.

Mirror spectacles which enhance binocular disparity by optically doubling the normal separation between the eyes were used to create conditions of combined perceptual and oculomotor conflict. Apparent depth and distance, as well as tonic accommodation, tonic vergence, and accommodative-vergence gain (response AC/A ratio), were assessed immediately before and after a 30 min exposure period of naturalistic viewing with the spectacles. Wearing the spectacles produced an increase in tonic vergence, and perceptual aftereffects consisting of increased apparent distance and depth. The results indicate that oculomotor conflict associated with enhanced interocular separation may be resolved through adaptation of tonic vergence, rather than through alteration of accommodative-vergence gain. The results also demonstrate that perceptual conflict between disparity and multiple veridical depth cues does not necessarily produce adaptive modification of the relationship between binocular disparity and apparent depth.

Accommodation, Ocular↗

PubMed2003

The visual control of reaching and grasping: binocular disparity and motion parallax.

The primary visual sources of depth and size information are binocular cues and motion parallax. Here, the authors determine the efficacy of these cues to control prehension by presenting them in isolation from other visual cues. When only binocular cues were available, reaches showed normal scaling of the transport and grasp components with object distance and size. However, when only motion parallax was available, only the transport component scaled reliably. No additional increase in scaling was found when both cues were available simultaneously. Therefore, although equivalent information is available from binocular and motion parallax information, the latter may be of relatively limited use for the control of the grasp. Binocular disparity appears selectively important for the control of the grasp.

Adaptation, Physiological↗

PubMed2004

Judging egocentric distance on the ground: occlusion and surface integration.

On the basis of the finding that a common and homogeneous ground surface is vital for accurate egocentric distance judgments (Sinai et al, 1998 Nature 395 497-500), we propose a sequential-surface-integration-process (SSIP) hypothesis to elucidate how the visual system constructs a representation of the ground-surface in the intermediate distance range. According to the SSIP hypothesis, a near ground-surface representation is formed from near depth cues, and is utilized as an anchor to integrate the more distant surfaces by using texture-gradient information as the depth cue. The SSIP hypothesis provides an explanation for the finding that egocentric distance judgment is underestimated when a texture boundary exists on the ground surface that commonly supports the observer and target. We tested the prediction that the fidelity of the visually represented ground-surface reference frame depends on how the visual system selects the surface information for integration. Specifically, if information is selected along a direct route between the observer and target where the ground surface is disrupted by an occluding object, the ground surface will be inaccurately represented. In experiments 1-3 we used a perceptual task and two different visually directed tasks to show that this leads to egocentric distance underestimation. Judgment is accurate however, when the observer selects the continuous ground information bypassing the occluding object (indirect route), as found in experiments 4 and 5 with a visually directed task. Altogether, our findings provide support for the SSIP hypothesis and reveal, surprisingly, that the phenomenal visual space is not unique but depends on how optic information is selected.

Analysis of Variance↗

PubMed1979

Information used in judging impending collision.

Many subhuman species and human infants, children, and adults can use two-dimensional information of relative rate of angular-size change to anticipate collisions between the self and approaching objects or surfaces. But extant studies have not determined what information is used when subjects view simulated approach events providing two-dimensional information and three-dimensional information (distance and distance change), as well as lower-order visual information contained in real approach events. Three experiments suggest that, given these several possibilities, adults' judgments of collision time are best predicted by two-dimensional spatiotemporal values which are invariant over object sizes, distances traversed, approach velocities, and several lower-order variables such as absolute angular size. However, collision time is substantially underestimated, with absolute amount of underestimation increasing as a function of actual time-to-collision. Large constant errors and loss of judgment linearity beyond about 10 s to contact time suggest that current models of human performances based on use of time-to-collision information require modified assumptions of operator efficiency.

Depth Perception↗