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Dental caries and fluorides in relation to fixed orthodontic treatment: a review.

This paper reviews the cariological aspects of fixed orthodontic treatment and discusses the role played by topical fluorides. During fixed orthodontic treatment, carious lesions may occur in the form of white spots. These may constitute an aesthetic problem. The clinical management of white spot lesions remains unresolved. In order to prevent development of these lesions, the use of topical fluorides is advocated. The need for patient co-operation in the use of self-administered topical fluorides is critical. To reduce this critical need, the use of fluoride-releasing orthodontic cements is recommended. The literature suggests that calcium fluoride, which is the major reaction product on enamel during topical fluoride application, plays an important role in the cariostatic mechanism.

Dental Bonding↗

Flexural strength and modulus properties of carbamide peroxide-treated bovine dentin.

BACKGROUND: The effects of carbamide peroxide bleach on tooth structure are uncertain. PURPOSE: The purpose of this study was to investigate the effects of direct or indirect carbamide peroxide application on dentin flexural strength and modulus in vitro. MATERIALS AND METHODS: Dentin bars were machined from bovine incisors and treated with 10% carbamide peroxide for 6 h/d for 14 days. Four groups were created, with eight bars in each group: group 1-direct bleach application only; group 2-indirect bleach application only; group 3-direct bleach application followed by a 2-week storage in artificial saliva; group 4-direct bleach application followed by a 2-week storage in artificial saliva and daily topical fluoride treatments. The specimens' flexural strength and modulus were tested after 24 hours, and the results were compared with water controls using independent t-tests (p < .05). RESULTS: Flexural strength results (in megapascals) for bleached versus control dentin (1=205+/-26 vs 215+/-14, 2=257+/-25 vs 261+/-14, 3=180+/-22 vs 193+/-36, 4=157+/-18 vs 184+/-11) were significantly lower in group 4 (p=.005). Modulus results (in gigapascals) for bleached versus control dentin (1=10.7+/-1.4 vs 12.2+/-0.6, 2=14.2+/-1.7 vs 14.4+/-1.6, 3=10.0+/-2.0 vs 10.9+/-1.3, 4=9.0+/-1.2 vs 11.1+/-1.0) were significantly lower in groups 1 and 4 (p=.013 and p=.003, respectively). There were no significant differences in strength and modulus results between the bleached and control dentin in groups 2 and 3. A direct application of carbamide peroxide to bovine dentin significantly decreased some dentin mechanical properties in vitro. An indirect application of carbamide peroxide to dentin did not significantly decrease dentin strength and stiffness. CLINICAL SIGNIFICANCE: This in vitro study suggests that a bleaching treatment, when applied to the enamel of intact teeth, does not significantly affect the mechanical properties of the underlying dentin. However, when applied directly to dentin in clinical situations such as root exposure or occlusal attrition, the bleaching treatment may result in altered mechanical properties of dentin. The clinical consequences of this observation are, however, unknown.

Animals↗

Caries prevalence among adults in communities with optimal and low water fluoride concentrations.

The aim of this study was to compare the dental health status of adults measured as caries prevalence in two socioeconomically similar communities with optimal and low water fluoride concentrations respectively. Other topical fluoride sources are also taken into consideration. The study is based on clinical and radiological examinations of 30-40-yr-old subjects who for all their lives have been drinking water with a fluoride concentration representative for the community. 260 individuals resident in the optimal fluoride area and 236 from the low fluoride are included in the study. The results show that caries prevalence was lower in the optimal fluoride area. Caries prevalence was higher in women than in men within both groups. The prevalence of primary caries was low but significantly higher in the low fluoride area, principally in the form of proximal caries. Caries prevalence was not influenced by other topical fluoride sources.

Adult↗

Failure of intense preventive efforts to arrest early childhood and rampant caries: three case reports.

This report presents the first three children who developed dental caries despite being enrolled in a randomized, control trial to test methods to prevent early childhood caries. The children's caretakers received education on decreasing frequent and prolonged feeding with a nursing bottle and other sugar containing foods, as well as brushing the children's teeth daily with 0.4% SnF2 gel. One of the child's caretaker additionally received training sessions to improve confidence in eliminating the child's nursing bottle habit and in performing daily tooth brushing. The two other children received monthly topical fluoride treatments with 2% NaF. Despite these intensive preventive efforts, these three children developed dental caries. Two of the children had mutans streptococci colonization at the time of initial visit, (12 and 14 months of age, respectively). All had high mutans streptococci levels at the time that caries was detected. Incorrigible, high-frequency sugar consumption from a bottle or from solid foods was suggested in all three cases. In one case, dental caries was associated with defects of the tooth enamel. Conceivably, the cariogenic challenge and harmful behaviors in certain children may be so extreme that they can overwhelm even extraordinary preventive efforts.

Bottle Feeding↗

The influence of saliva on the formation of calcium fluoride-like material on human dental enamel.

After a topical fluoride application two resulting features can be observed and measured: the formation of calcium fluoride and a decrease in caries incidence. For the formation of solid calcium fluoride the source of calcium may be either the enamel itself or remaining saliva or--in plaque--plaque fluid and calculus. The aim of the present study was to examine whether saliva through its calcium content has any influence on the amount of calcium fluoride formed by a topical fluoride treatment of enamel. The roots and the fissure systems of 64 freshly extracted intact third molars were covered with nail varnish and allocated to eight groups of 8. Half of the groups were put in fresh paraffin-stimulated saliva for 5 min after which surplus of saliva was shaken off whilst the other groups remained in distilled water. The teeth were given a 2-min topical treatment with either distilled water (control), neutral 0.2% NaF, neutral 2% NaF or 2% NaF acidified with 0.1 mol/l H3PO4. After the topical treatment the teeth were rinsed in running tap water for 5 min, dried and revarnished before determination of calcium fluoride. It was found that the amount of calcium fluoride formed depended on the concentration of fluoride (the higher the fluoride concentration, the higher was the amount of calcium fluoride), the acidity of the solution (presumably due to the increase in available calcium through enamel dissolution) and the presence of saliva (presumably due to its calcium content and its mucinous nature). As there was always more calcium fluoride formed in the presence of saliva, thorough drying of the teeth prior to topical treatments may be superfluous.

Analysis of Variance↗

Caries risk after interproximal enamel reduction.

INTRODUCTION: Air-rotor stripping (ARS) is a commonly used method to alleviate crowding in the permanent dentition. Its widespread acceptance, however, has been limited by the potential increase in caries risk of the abraded enamel surface. The aim of this study was to compare the susceptibility of ARS-treated enamel surfaces with intact surfaces in patients undergoing fixed orthodontic therapy. METHODS: Forty patients treated with ARS were examined clinically and radiographically for caries 1 to 6 years after interproximal enamel reduction. All patients were seen by their dentists for prophylaxis at 6-month intervals during active orthodontic treatment and were exposed to fluoridated water and toothpaste. Topical fluoride agents or sealants were not applied on the abraded surface after any ARS session. Caries incidence was compared between ARS-treated and unaltered surfaces within subjects. The decayed, missing, filled tooth (DMFT) and surface (DMFS) scores were used to evaluate the subjects' overall caries risk. RESULTS: Totals of 376 test and 376 control surfaces were examined. The number of interproximal lesions detected was found to be low with no statistically significant difference detected between the groups (test = 3; control = 6; P = .33]. The DMFT and DMFS scores increased significantly during the study period, indicating that these patients were clearly at risk of tooth decay (P <.001). CONCLUSIONS: The findings indicate that the risk of caries is not affected by ARS. Furthermore, our data show that the application of topical fluoride on the enamel surfaces immediately after ARS in patients exposed to fluoridated water and fluoride-containing toothpaste may not provide any additional benefit.

Adolescent↗

The effect of titanium tetrafluoride (TiF4) application around orthodontic brackets.

In the present in vivo study, the cariostatic potential of a titanium tetrafluoride (TiF4) solution applied topically around orthodontic brackets was investigated with quantitative microradiography. Also characteristics of the TiF4-treated enamel surface were examined with scanning electron microscopy (SEM). Ten pairs of premolars to be extracted for orthodontic treatment were used in the first part of this study. Brackets were bonded on all teeth with an orthodontic adhesive, and 10 randomly selected premolars served as controls, whereas a similar number were treated with 1% TiF4 around brackets for 60 seconds. After 4 weeks with no topical fluoride supplementation, all teeth were extracted and stored for analysis. Results indicated the 1% TIF4 solution reduced lesion depths and total mineral loss, at the bracket periphery, significantly during the 4-week period. The presence of a surface coating was demonstrated by SEM micrographs. It was concluded that TiF4 may provide a high level performance as a prophylactic agent for orthodontic purposes.

Child↗

Oral health status of patients 5-6 years after placement of cobalt-chromium removable partial dentures.

This study is a clinical survey of cobalt-chromium (Co-Cr) removable partial denture (RPD) wearers that aimed to investigate the effects of denture wearing on oral tissues. A random sample of patients who had received their dentures 5-6 years previously from a dental teaching hospital in Hong Kong was selected. Those who had been constantly wearing the RPDs were examined by one calibrated examiner under an optimal clinical setting. The patients' dental, periodontal and mucosal status were assessed. A total of 87 patients were examined. Mucosal lesions under the Co-Cr RPDs were uncommon in this study sample. However, there was a high prevalence of plaque, gingivitis and gingival recession, especially in dento-gingival surfaces in close proximity (within 3 mm) to the dentures. Thus, there is a special need for regular oral hygiene reinforcement, scaling and prophylaxis among RPD wearers. Despite a low caries incidence in the study sample, root caries were found to be associated with contact with the RPDs (P < 0.05) but coronal caries were not. It is recommended that coverage of the exposed root surfaces by RPD components should be avoided. Also, topical fluorides should be regularly applied onto exposed root surfaces as a preventive measure.

Adult↗

Marginal bone height in adolescents participating in different preventive dental care programs.

A radiographic evaluation was made of the marginal bone height in youth, subject to different preventive dental care regimens. A test group consisted of 14-15-year-olds who for 4 years had received preventive dental care based on oral hygiene education, professional tooth cleaning and topical fluorides and/or mouth rinsings every 3rd week. A comparison group had been given solely fluoride mouth rinsings every 2nd week with no particular emphasis on oral hygiene measures. The radiographic evaluation showed average differences between the investigated groups of less than 0.3 mm in the distance from the cementoenamel junction to the alveolar bone crest. In the mandibular premolar-molar region of the comparison group, the marginal bone height differed significantly from the corresponding region in the test group. No such differences in the maxillary regions were noted. The clinical relevance of the results is discussed.

Adolescent↗

Increment of dental caries among Finnish dental students during a period of 2 years.

The purpose of the study was to estimate the increment of dental caries among dental students in Helsinki, who acquired good knowledge of caries prevention during their studies. The group (59 students) was examined twice with an interval of 20.2 +/- 4.1 months. Clinical findings, augmented with bitewing radiographs and an orthopantomogram, were recorded separately for each tooth surface, and individual DMFS and DS index scores were computed. In addition, the students were interviewed with regard to oral hygiene, topical fluoride application, and dietary habits. The mean DMFS and DS index scores at the first examination were 45.0 and 9.1, respectively. At the second examination, DMFS was 46.4 and the number of new decayed surfaces per student 0.54/year. Both the latter values indicated that caries progression was slow. The increment of dental caries among the dental students was much smaller than that observed earlier among other groups of university students in Finland. Further evidence that caries progression among the dental students was slow was provided by the finding that of the 318 incipient caries lesions recorded at the first examination, no more than 11 had developed into clinical caries by 20 months.

Adult↗

Can organised dental care for children be both good and cheap?

Children's dental services evolved from emergency, pain-relieving and later amalgam-based care systems of the early and middle 20th century. The pattern of occurrence of dental caries is different today and young teenagers have very few teeth affected by caries. Restoration of lesions in permanent teeth, typically on occlusal or buccal/lingual surfaces, is technically simple. Paradoxically, dental students today are expected to master a vast amount of knowledge, including information on new dental materials and techniques. New dentists who choose to provide dental care for children as a career will spend most of their days placing fissure sealants, applying topical fluorides and inserting predominantly single-surface restorations. Because of their expensive training, new dentists will nevertheless expect high earnings, and this results in a high cost for children's dental care. The opportunity cost is other health services foregone. In developing countries where there are few dentists, they are almost not available for children at all. Costs could be reduced by reducing the number of interventions, and by reducing staff costs. Fewer interventions could be achieved by longer recall intervals: several studies and experience from places where this has been implemented indicate that is safe and effective. Widespread delegation of operative work to appropriately trained dental hygienists or therapists would reduce staff costs. Dental therapists are better substitutes for dentists in children's care because they are trained to do most of the clinical procedures that are necessary in children's dentistry. In Western Australia and South Australia, most dental care for children is provided by dental therapists. The costs of care are much lower and the outcome, as measured by caries experience and numbers of treated patients, is equivalent to or even better than European dentist-based services. Already, in some places, politicians and others are querying the need for organised children's dental care. Increased effectiveness will make continuation of children's dental services easier to sustain.

Adolescent↗

Oral hygiene in the control of occlusal caries.

Occlusal pit and fissure caries accounts for a high proportion of the total caries burden among children. Studies from Denmark suggested that oral hygiene measures may be effective in the control of occlusal caries in permanent teeth. This study reports on the findings after 24 months of a controlled field trial comparing the caries-preventive effects of a professional tooth-cleaning and dental health education programme (test) with a standard preventive programme (control), comprising selective fissure sealing and application of topical fluorides. School Dental Service clinics of the Health Department of Western Australia, in Perth, were assigned to four test or four control clinics. Schoolchildren, mean age 6 years, with sound newly erupted first permanent molars were included in the study (207 test, 197 control). After 24 months, 179 test and 156 control children were examined by a calibrated examiner who was 'blind' to the test or control status of the child. Thirty-two test and 31 control children developed occlusal caries on the first permanent molars; the estimated risk ratio was 0.90 (95% CI 0.58-1.41). Children in both groups had an average DMFT score of 0.30. The 24-month results suggest that the two preventive programmes did not differ with respect to the control of occlusal caries in newly erupted molars.

Analysis of Variance↗

The index of ADOH: concept of measuring oral self-care functioning in the elderly.

Measures of ability, or function, are used in the health field to determine the level of performance of a specific task, assess the loss of function, and to measure the return to function as a result of rehabilitation or interventions. While these measures are important to all age groups, it is the elderly and chronically ill who are at most risk for adverse changes in their health and functional status. The Index of the Activities of Daily Oral Hygiene (ADOH) is an instrument to assess and monitor functional dependency in manipulating aids used in oral self-care. It is part of the overall concept of oral self-care which subsumes function, education and training, and compliance in achieving and maintaining oral health. The purpose of the Index of ADOH is two-fold: to assess a subject for the progressive loss of the physical ability to manipulate the aids used in oral self-care, and to measure the return to function in response to care intervention and rehabilitative services. These manipulative tasks are associated with flossing, brushing, topical fluoride application, and the use of oral rinses. Aside from changes in function, the Index of ADOH can be used by health care providers and administrators to project the need for services or support for home care.

Activities of Daily Living↗

Effects of pH and calcium on hydrolysis of Na2SiF6 and Na2SnF6. A quasi-constant composition titration study.

In the present work, hydrolysis reactions of sodium hexafluorosilicate (Na2SiF6) and sodium hexafluorostannate (Na2SnF6) were studied at various combinations of pH and calcium ion (Ca2+) concentrations using a quasi-constant composition titration method. Under high concentrations of hydrogen ion (H+) and Ca2+, the promoting effect of Ca2+ on the hydrolysis of Na2SiF6 was stronger than the inhibition effect of H+. However, the inhibition effect of H+ on the hydrolysis of Na2SnF6 was stronger than the promoting effect of Ca2+. Na2SiF6 and Na2SnF6 were found to have hydrolysis properties that may make them suitable for use with an acidic calcium phosphate solution in a topical fluoride treatment which forms dicalcium phosphate dihydrate as an intermediate.

Calcium↗

Comparison between evaluation methods for the anti-caries efficacy of monofluorophosphate-containing dentifrices.

A comparison is described of three methods of preclinical assessment of potential anti-caries efficacy for topical fluoride treatments. Methods are compared using dentifrices containing 1,000, 1,500 and 2,500 ppm F as sodium monofluorophosphate (SMFP). These formulations have been shown elsewhere to give a statistically significant dose response of increasing anti-caries efficacy [Stephen et al., 1988]. An in situ enamel insert model, oral fluoride pharmacokinetics and F uptake to demineralised enamel are all shown to correlate with clinical efficacy for the test dentifrices studied.

Adult↗

Ion probe study of fluorine gradients in outermost layers of human enamel.

F concentrations in the outermost layers of human tooth enamel were studied with the aid of a secondary ion microanalyzer. Concentration profiles were recorded in continuous sputtering analysis from the surface down to a depth of about 0.3 micrometer. Samples previously subjected to topical fluoride treatment were compared with reference specimens. In some samples, the results were compared with those obtained at greater depths by macroscopic etching analysis.

Acid Etching, Dental↗

Prevention of xerostomia-related dental caries in irradiated cancer patients.

Three caries preventative regimens: oral hygiene; oral hygiene and topical fluoride; and oral hygiene, typical fluoride, and sucrose restriction were evaluated in patients with cancer given xerostomia-producing radiotherapy. The oral hygiene-fluoride gel combination was remarkably effective in protecting these high risk patients from caries, regardless of the cariogenicity of the diet.

Adolescent↗