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At least 415 records · Page 23Linked to original sources
PubMed1998

Variation in taste of topical lignocaine anaesthesia for gastroscopy.

AIM: To study the distribution and determinants of taste variation for lignocaiine spray (Xylocaine; Astra Pharmaceuticals, King's Langley, UK). METHODS: Sixty-nine patients (male:female 49:20, mean age 48.5 years) attending for open access upper gastrointestinal endoscopy were studied. Taste perceived after applying 4 doses (40 mg) of lignocaine spray to the oro-pharynx was recorded prior to endoscopy. RESULTS: 37/69 (54%, 95% CI: 41-66%) perceived the taste of the lignocaine spray as bitter. whilst 24/69 (35%, 95% CI: 24-47%) and 6/69 (9%, 95% CI: 3-18%) perceived the taste as either fruity/sweet or tasteless. The variation in taste did not correlate with either demographic features or H. pylori inflection, but duodenal ulceration was slightly more common amongst bitter tasters. CONCLUSION: The taste of lignocaine is not uniform, but the basis of this variability is uncertain.

Administration, Topical↗
PubMed1994

Serum lidocaine and MEGX concentrations after pharyngeal anesthesia for gastroscopy.

In 20 patients undergoing topical anesthesia for gastroscopic examination, serum concentrations of lidocaine and its metabolite, monomethylglycinexylidide (MEGX), were measured. Patients were divided randomly into two groups: a gel group, in which 5 ml of 2% lidocaine gel was applied to the throat for 20 minutes; and a solution group, in which 40 ml of 2% lidocaine solution was administered by gargling for five minutes. The effect of oropharyngeal anesthesia was comparable in both groups. In the gel group, the serum levels of lidocaine and MEGX were not elevated at 15 minutes after application of the anesthetic. However, in the solution group, a rise in both serum lidocaine and MEGX at 15 minutes after anesthesia was detected in some of the patients (40%). Increased serum MEGX concentrations, which correlated well with serum lidocaine concentrations, were associated with the age of the patient (r = 0.606; p < 0.05), but not with height or weight. As a topical anesthetic for endoscopic examination, we prefer lidocaine gel to lidocaine solution, because the latter might be absorbed more rapidly and unpredictably in some, especially aged patients.

Adult↗
PubMed1993

Through the nose gastroscopy for the placement of feeding tubes.

Following local anesthesia to the nose, through-the-nose (TTN) passage of a paediatric gastroscope was successful and well tolerated in 82 of 92 patients on whom it was attempted in order to place nasogastric feeding tubes. This technique allows for guidewire placement to be used for insertion tubes or dilators. The ten failures we observed occurred in patients with bilateral narrow turbinates. We conclude that the TTN approach is quicker and easier than conventional methods of feeding tube placement allowing for an additional endoscopic evaluation of the upper GI tract.

Adult↗
PubMed1981

Jejunogastric intussusception, an acute exacerbation diagnosed by gastroscopy.

A case of acute jejunogastric intussusception is reported. The patient had suffered intermittent attacks for 7 years, and had an acute fulminating attack prior to the present admission. Chronic recurrent jejunogastric intussusception should be considered a possible cause of pain and vomiting in patients who have had gastrojejunostomy or gastric resection.

Acute Disease↗