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Results for “INSEMINATION, ARTIFICIAL”

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PubMed1983

Necessity of formal genetic screening in artificial insemination by donor.

After observing abnormal offspring following artificial insemination by donor, several authors recently have proposed intensive genetic screening of donors. The screening would be beyond that practiced by most infertility specialists. To determine the necessity for formal genetic investigation of donors, the authors analyzed the outcome of artificial insemination pregnancies in which donors were screened with careful medical and family histories, but were not subjected to formal pedigree analysis, karyotyping, or extensive metabolic screening. Fewer than 10% of potential donors were disqualified for genetic reasons. The study, limited to ascertaining the presence or absence of overt anomalies evident at birth, showed that such malformations were not more frequent in artificial insemination pregnancies (1.7%) than in controls (2.3%). It is concluded that extensive and formalized genetic screening is probably not necessary provided a thorough medical history is obtained. In addition, a practical approach to identifying donors at increased risk for siring abnormal offspring is offered.

Adult↗

PubMed1988

Seasonal distribution in conceptions achieved by artificial insemination by donor.

The distribution of conceptions after artificial insemination from a donor was studied in 259 conceptions at an artificial insemination clinic and found to be seasonal. Conception was not influenced by the number of donors or patients attending the clinic, the frequency of inseminations, or medical skill. Conception was more common from early winter until early spring (October to March) with a peak in November. As variables such as frequency of intercourse and ovulation were irrelevant in these women and highest sperm counts occur from February to March these results suggested a seasonal variation in the quality of the ovulated egg or endometrial receptivity. The waste of eggs after ovulation (or preimplantation conceptuses) at specific times of the year has implications in the treatment of infertility, particularly for in vitro fertilisation and gamete intrafallopian transfer.

England↗

PubMed1976

Equine artificial insemination.

The use and techniques of artificial insemination for horses in Germany over the last 30 years is described. Artificial insemination appears to produce pregnancy percentages equal to those from normal breeding methods and its continued availability under veterinary supervision is recommended in conditions where disease, disability or distance debar normal service.

Animals↗

PubMed1980

Artificial insemination of subtropical commercial beef cattle following synchronization with cloprostenol (ICI 80996): II. Estrous response.

Data collected from two controlled breeding field trials involving 561 Bos indicusxBos taurus cows and heifers were analyzed for estrous and fertility response following a cloprostenol ICI-80, 996 (CLP) synchronization regime. Fertility data were discussed in a companion paper (1). In Trial 1, 128 animals were assigned to four treatments: 1) controls which were inseminated at the naturally occurring estrus; 2) Animals artificially inseminated at approximately 72 hr and 96 hr following a second CLP; 3) Animals artificially inseminated at approximately 72 hr following a second CLP; and 4) Animals artificially inseminated approximately 12 hr after detection of estrus post-second CLP. Trial II included 391 heifers distributed among six treatments: 1) Artificially inseminated between 70 and 90 hr post-second CLP; 2) Sham inseminated between 70 and 90 hr post-second CLP; 3) Processed with no manipulation of the genital tract between 70 and 90 hr post-second CLP; 4) Artificially inseminated approximately 12 hr after the detection of estrus following a second CLP; 5) Artificially inseminated at the naturally occurring estrus and 6) Non-treated heifers exposed to fertile bulls. Cloprostenol ICI-80996 was effective (P<.01) in synchronizing estrus in comparisons of treated vs non-treated controls in Trials I and II (82 vs 29%; 57 vs 19%, respectively). However, a significant reduction in the expression of estrus was observed following Timed AI when compared to heifers bred 12 hr after detection of CLP-induced estrus in Trial II (37 vs 54%, P<.05). The authors conclude that a single timed insemination of Brahman crossbred heifers suppresses the behavioral expression of estrus. Other evidence (1) indicates that the fertility during this period is similarly reduced.

Journal Article↗

PubMed1950