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At least 415 records · Page 23Linked to original sources
PubMed2000

Diabetes and life-styles: role of physical exercise for primary prevention.

Regular physical exercise has been known to be beneficial in the treatment of type 2 diabetes. Epidemiological studies of physical exercise: previous non-randomized studies suggested that a life-style intervention program involving diet and/or exercise reduced the progression of impaired glucose tolerance (IGT) to type 2 diabetes. Recent randomized controlled intervention trials also showed that diet and/or exercise intervention led to a significant decrease in the incidence of diabetes among those with IGT. Endocrinological and metabolic effects of exercise: in well controlled diabetic patients, physical exercise promotes utilization of blood glucose and lowers blood glucose levels. On the other hand, in poorly controlled diabetic patients with ketosis, physical exercise results in further rises in blood glucose, free fatty acids and ketone body concentrations. Long-term gentle regular jogging increases insulin action in respect of both carbohydrate and lipid metabolism despite no influence on body mass index or maximal oxygen uptake. A significant correlation was observed between deltaMCR (insulin sensitivity) and average daily steps Our recent data suggested that the improvement of insulin action by physical exercise was attributed, at least in part, to the increase in insulin-sensitive GLUT4 (glucose transporter 4) on the plasma membrane in skeletal muscle. In conclusion, as an adjunct to other forms of therapy, mild regular physical exercise will play an important role in primarily preventing type 2 diabetes.

Adult↗
PubMed1988

Life-style risk factors for pancreatic cancer in Louisiana: a case-control study.

A hospital-based, incident case-control study of pancreatic cancer was conducted between 1979 and 1983 in parallel with similarly designed studies of lung and stomach cancers in high-risk areas of Louisiana. To evaluate life-style practices, including diet, the authors pooled controls from the three studies, and then excluded subjects with diet-altering chronic diseases. When the 363 cases were compared with the 1,234 identified controls, significantly elevated risks were found among persons with Cajun ancestry, especially in rural areas. Among current smokers, a significant twofold risk was associated with moderate (16-25 cigarettes per day) and heavy (greater than or equal to 26 cigarettes per day) consumption, while ex-smokers showed no consistent pattern of risk. After adjustment for potential confounding by smoking, diet, and demographic factors, the risk of pancreatic cancer was unrelated to use of alcoholic beverages or coffee. Pork products and rice were conspicuous as dietary risk factors, each showing a positive dose-response effect, whereas fruit consumption exerted a protective influence.

Aged↗
PubMed2002

Life-style vaccines.

Multiple immunotherapy approaches are under development to treat various chronic diseases or conditions. Thanks to dramatic technological improvements, the field of vaccinology can now extend from prophylaxis to therapy, and from infectious diseases to dysimmune disorders like cancer or autoimmunity, or even to non-immune related conditions, including neurological or cardiovascular disorders. Life-style vaccines defined as vaccines to manage chronic conditions in healthy individuals can, therefore, also be envisaged. Three examples will be reviewed and discussed here, from both technical and ethical aspects: contraceptive vaccines, vaccines to treat addictions, and anti-dental caries vaccines.

Dental Caries↗
PubMedDate not supplied

[Life-style of medical personnel dwelling and working in agroindustrial area].

Results of sociological survey of medical personnel of typical agroindustrial area of Novgorod Oblast are presented. Data of self-registration of acute and chronic diseases and self-appraisal of one's health testify higher morbidity and health deterioration during last 3 years. Analysis of demographic characteristics, life-styles and labor conditions revealed complex of major factors impacting individual health and flow-out of professional medical personnel. Both amount of average monthly wage of physicians and paramedics, levels of their family income and welfare and as well degree of their inconsistence with cost of living of able-bodied population are established. Conditions of living and social maintenance, labor and off-labor activity, attitude to one's own health and spread of risk factors were analyzed. Management weaknesses of district and rural patient care institutions were established, including considerable exceeding of hygienic regulations established for medical personnel working load and higher spread of physical, chemical and biological risk factors of working environment harmful for health. Need in further enhancement of management of working process, occupational safety, labor remuneration and in increasing social safety, hygienic and curative activity of medical personnel is justified.

Adult↗
PubMed2003

Respiratory symptoms correlating to smoking prevalence: the National Nutrition Survey and the National Life-style Survey in Japan.

BACKGROUND: Although the fact that smoking habits have adverse effects on health, whether the high proportion of smokers elevates the prevalence of symptoms relating to the smoking in a community is still unknown. METHODS: An ecologic study about whole Japan was conducted. Age-adjusted smoking prevalence was calculated using the National Nutrition Survey data from 1986 through 1995 by prefecture and sex. Age-adjusted respiratory symptom prevalence were observed using the National Life-style Survey data in 1995. Correlation among 46 and/or 43 prefectures was examined by sex. RESULTS: There was a negative correlation between smoking prevalence and wheezing prevalence among males (r = -0.301). Among females, positive correlations were observed on the symptoms of nasal obstruction (r = 0.355), nasal discharge (r = 0.344), sore throat (r = 0.481), cough (r = 0.350), sputum (r = 0.594), wheezing (r = 0.451), palpitation (r = 0.363), dyspnea (r = 0.587), and frontal chest pain (r = 0.472). CONCLUSIONS: Smoking prevalence was deeply related to respiratory symptoms among females in Japan.

Female↗
PubMed1996

Social status, life changes, housing conditions, health, functional abilities and life-style as risk factors for recurrent falls among the home-dwelling elderly.

OBJECTIVE: To define the risk factors for recurrent falls in the home-dwelling elderly. DESIGN: A prospective population-based study covering two years. SETTING: Five rural municipalities around the city Oulu, northern Finland. PARTICIPANTS: All home-dwelling elderly persons (N = 1,016) aged 70 years or older living in the municipalities. OUTCOME MEASURES: The risk factors of recurrent falling by variables related to social status, life changes, housing conditions, health, functional abilities and life style, using cross-tabulations and multivariate analyses. RESULTS: The recurrent fallers (at least two falls within 365 days after the examination day) consisted of 17 men (6% of the men) and 71 women (14%). Logistic regression analyses showed female sex, urinary urgency, frequent fear of falling, dizziness, a poor pulse rate rise 30 seconds after standing up and falling during the previous year to be risk factors for recurrent falls. After the variable representing previous falls had been removed from the analysis, urinary incontinence and a change in housing conditions during the past two years emerged and urinary urgency dropped out of the model. CONCLUSIONS: Women particularly are a target group for the prevention of falls among the elderly. Urinary urgency and urinary incontinence, fear of falling, dizziness and changes in the housing conditions should be inquired about to identify the elderly at risk for falling and to take preventive interventions. In addition to testing blood pressure changes after standing up, the changes in pulse rate should be determined to identify and treat elderly people who have orthostatic conditions.

Accidental Falls↗
PubMed1987

Heavy metal levels in two biennial pine insects with sap-sucking and gall-forming life-styles.

The concentrations of cadmium, copper, nickel and lead were studied in two biennial pine insects in relation to the deposition of heavy metals in the environment around the industrialised town of Harjavalta in southwestern Finland. Sap-sucking pine bark bugs, Aradus cinnamomeus (Heteroptera, Aradidae), and gall-forming pine resin gall moths, Petrova resinella (Lepidoptera, Tortricidae) were collected on sample plots located at logarithmic distances along 9 km-long transects from the distinctive emission source. The responses of these insects representing different life-style were compared. Heavy metal concentrations in A. cinnamomeus were highest (Cd 17 microg g(-1), Cu 1900 microg g(-1), Ni 220 microg g(-1), Pb 32 microg g(-1)) in the vicinity of the factor complex, and lowest in the outermost zones. This trend followed a linear regression model. The pattern was less clear in P. resinella, the concentrations being only one-tenth of those recorded in A. cinnamomeus. Correlations between metal levels in A. cinnamomeus and previously examined Sphagnum moss bags proved to be highly significant in every case. The differences in the heavy metal concentrations of these two insect species, which occupy the same trophic position, would appear to be due to the differences in their feeding characteristics. Heavy metals accumulate in the posterior bulb of the midgut in the discontinuous alimentary system of A. cinnamomeus, while P. resinella is likely to secrete most of the metals into the walls of the galls. The almost total absence of these two insect species near the factory complex seems to be associated with the high concentrations of metals.

Journal Article↗