Characteristic of cholinoreception in somatic muscle of the lamprey, Lampetra fluviatilis.
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Acetylcholine↗
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Results for “Methacholine Compounds”
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
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The effect of cholinergic antagonists on the response to acetylcholine, acetyl-beta-methylcholine and nicotine of neurones of Helix aspersa.
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Acetylcholine↗
Temperature sensitivity of the avian salt gland.
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Animals↗
Iontophoretic application of acetylcholine and GABA onto insect central neurones.
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Acetylcholine↗
Some aspects of electrolyte and water balance in three estuarine reptiles, the diamondback terrapin, American and "salt water" crocodiles.
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Acclimatization↗
Effect of cold storage on the response of guinea-pig taenia coli to certain catecholamines and other agents.
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Adenosine Triphosphate↗
Mechanism of selective cardiac vagolytic action of pancuronium bromide. Specific blockade of cardiac muscarinic receptors.
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Acetylcholine↗
Sensitization of the calf tracheal muscle to beta-adrenergic bronchospasmolytics by beta-haloalkylamines and cocaine.
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Animals↗
Studies on thyroid-catecholamine interactions in the isolated rabbit heart.
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Animals↗
The model of functional interaction. I. Development and first check of a new model of functional synergism and antagonism.
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Binding, Competitive↗
The model of functional interaction. II. Experimental verification of a new model: the antagonism of beta-adrenoceptor stimulants and other agonists.
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Adrenergic beta-Agonists↗
Modulating effect of central adrenergic neurones on a vagally mediated cardioinhibitory reflex.
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Acetylcholine↗
Temperature responses in the rat and cat to cholinomimetic drugs injected into the cerebral ventricles.
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Acetylcholine↗
Changes in the sensitivity to cholinomimetic drugs of smooth and cardiac muscle in the rat induced by subacute administration of di-isopropyl phosphorofluoridate.
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Acetylcholine↗
The antagonism between cholinomimetic agonists and beta-adrenoceptor stimulants. The differentiation between functional and metaffinoid antagonism.
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Adrenergic beta-Agonists↗
The effect of 4-(1-naphthylvinyl)-pyridine (NVP), a choline acetylase inhibitor, on autonomically innervated tissues of the rat.
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Acetylcholine↗
Effect of full agonists following calcium deprivation in rat vas deferens.
The contractile effects of maximum doses of adrenaline, noradrenaline, methacholine, acetylcholine, serotonin and barium chloride were studied following substitution of a medium without calcium for the normal nutrient solution. Except for the last agonist, the effects fall to about 10% within the first 3 min with prompt return to normal value upon reintroduction of regular fluid. This recovery is, however, slower if the previous incubation in Ca-free solution is prolonged. When barium chloride is used in a calcium-free medium, the maximum height of contractions falls exponentially at a t1/2 of about 180 min. This decay can be accelerated by giving successive 5-min doses of the agonist or by using EDTA. It is hypothesised that excitation--contraction coupling in rat vas deferens depends on at least two different calcium sources: a deep site associated with the effects of barium, and a superficial one, related to the other agonists. To explain the slow recovery after prolonged calcium lack, a third compartment in series with the latter is suggested. No indication is found that the biphasic effects of barium depend on two different calcium pools.
Acetylcholine↗
Drug effects in a novel biphasic writing syndrome induced by acetylcholine in mice.
The writing induced in mice by i.p. administration of 3 mg/kg acetylcholine chloride showed a biphasic response with time. The primary phase of 1-15 sec after acetylcholine appeared to be the result of nicotinic receptor stimulation. The secondary phase from 30 sec following acetylcholine was selectively suppressed by anti-inflammatory agents and by atropine, while centrally acting analgesicw, other strong central nervous system drugs and ganglion blockers suppressed both phases of writhing to an equal extent. The narcotic partial agonists significantly suppressed primary writhing more readily. The method appears to be of value in testing new pharmacological agents.
Acetylcholine↗