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Results for “Peripheral Nervous System Neoplasms”

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At least 415 records · Page 23Linked to original sources
PubMed1992

[Tumors of the adrenal gland and lumbar sympathetic chain. Differential ultrasound diagnosis in childhood].

In a retrospective study from 1979 to 1989 17 tumors of the sympathic chain and the adrenal gland were analysed according to typical sonographic patterns. 13 tumors (10 neuroblastomas, 2 pheochromocytomas, 1 adenoma of the adrenal gland) were localized within the abdomen, 4 tumors (3 neuroblastomas, 1 ganglioneuroma) originated from the mediastinum. Neuroblastomas usually were great suprarenal masses with bad delineation and inhomogenous increased echogenicity in comparison with the liver. In more than 50% calcifications occurred, whereas cysts (15%) could rarely be found. The upper pole of the ipsilateral kidney usually was compressed and displaced caudally and laterally. The great intraabdominal vessels were usually displaced anteriorly and to the opposite side. The disturbed flow within the compressed intraabdominal vessels could reliably be shown by colour Doppler sonography as well as tumor vascularity. The 2 pheochromocytomas as well as the ganglioneuroma and the adenoma of the adrenal gland were round or oval, well delineated nodules with homogeneous liver like echogenicity. According to their typical sonographic patterns tumors of adrenal gland and sympathic chain can be differentiated from each other as well as from kidney tumors.

Abdominal Neoplasms↗
PubMedDate not supplied

[Polyradiculoneuritis in visceral cancer. Review of the literature. Apropos of 2 cases].

One should distinguish two types of polyradiculoneuritis during visceral carcinoma. Metastic polyneuritis and paraneoplastic polyneuritis. They fulfil distinct anatomical criteria and their pathogenesis is different. Both, however, have clinical analogies and a similar course. The survival time in both types is usually a few weeks. It rarely exceeds one year.

Adult↗
PubMed1990

[Mesenchymal extra-skeletal chondrosarcoma. Apropos of a case].

The authors report a case of extra-skeletal mesenchymal chondrosarcoma in a 22 year old man. This rare tumour developed along the nerve tracts (nerve roots, sciatic nerve and gluteal nerves) with contiguous involvement of muscles and three different bones (vertebra, sacrum, iliac bone). The nature of the tumour could only be determined by histological examination of a large fragment.

Adult↗
PubMed1988

[Spinal gliomas including ependymomas].

Within a period of 35 years a total of 570 spinal tumours included 77 intramedullary gliomas (44 astrocytomas and 33 ependymomas including those located in the conuscada region). Initial symptoms, neurological findings at the time of the admittance to the clinic as well as results of the operation are presented. The importance of an early diagnosis is pointed out.

Adolescent↗
PubMed1979

[Development of experimental peripheral nerve tumors in hormonal imbalance].

According to the data obtained by the authors, some modifying factors, and in particular artificial disorders of hormonal balance in rats, influence the realization of the blastomogenic effect of methylnitrosourea. The results of these studies indicate that the manifestation and the development of tumors in the peripheral nerves occurs more rapidly and easier in experimental hypothyrosis due to a daily administration of anti-thyroid drugs (merkazolyl) and an estrogenation of the organism of animals by a monthly subcutaneous suturation of sinestrol pills. In castration and administration of thyroid hormones (thyroidin) the amount of experimental neurogenic newgrowths decreases with an extension of the latent period of their development.

Animals↗
PubMedDate not supplied

Broad phase II study of vindesine.

A broad phase II study of vindesine was conducted in 79 adults with advanced malignancies. Most patients had solid tumors, particularly adenocarcinomas (59%), and 67 patients had received prior chemotherapy which included vincristine in 24 patients and vinblastine in one. Depending on tolerance to previous therapy, patients received vindesine at doses of 3-4 mg/m2 administered iv at 2-week intervals. Objective tumor regressions were seen in eight of 36 patients (one complete response, one partial response [PR], and six minor responses) with colorectal cancer, one of four patients (PR) with squamous cell cancer of the esophagus, one of four patients (PR) with malignant melanoma, and one of two patients (PR) with lymphoma. Five of 11 responding patients had received vincristine previously. Toxic effects were manageable. The results of this study justify in-depth, disease-oriented phase II evaluations of vindesine, regardless of prior therapy with other vinca alkaloids.

Adolescent↗