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The authors report on a newborn with two uncommon causes of bleeding. Platelet alloimmunization in PLA system was associated with galactosemia proved by the galacto uridyltransferase assay. The immediate outcome was favourable. The authors discuss the problem of diagnosis raised by this association.
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A case of severe thrombocytopenia (27 x 10(3)/mm3) of early onset during unfractionated heparin (Héparine sodique Rovi) treatment is reported in a 75 year-old man suffering from a deep vein thrombosis of the right calf. It was not associated with thromboembolic or haemorrhagic complications. A serum heparin-dependent aggregating factor was not detected. Substitution of low molecular weight heparin (Choay Laboratory, CY 222, PM 4 500, 25 000 U anti-Xa/ml) for unfractionated heparin resulted in a progressive normalisation of the platelet count and improvement of the venous thrombosis.
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