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Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

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At least 415 records · Page 23Linked to original sources
PubMed2006

[What does "p" mean at conclusion of a test of hypothesis in a randomized controlled clinical trial of superiority?].

The aim of this statistical note, the sixth in the series, is to introduce the rationale of the test of hypothesis suitable for comparing the effect of two treatments in a randomized controlled clinical trial of superiority. The presentation takes advantage of the analogy with a criminal trial debate based upon circumstantial evidence in an Italian Court. The results of three randomized controlled clinical trials: ISIS-1, AIMS and RESTORE are introduced and proper ways for their interpretation are suggested.

Randomized Controlled Trials as Topic↗
PubMed1991

Outline of the ISS code for the classification of chemical substances for use in compiling a national inventory.

A coding system for categorizing all types of compounds was developed specifically as part of the National Inventory of Chemical Substances to be applied by the Istituto Superiore di Sanità (ISS) in order to comply with the EEC present legal provisions on chemicals in trade. A number of applications were also described to illustrate the coverage and the adaptability of the code.

Chemical Phenomena↗
PubMed1991

[The consistency and validity of a measurement in clinical pediatric research. Its definition, evaluation and interpretation].

In clinical pediatric research as in all research, one of the fundamental characteristics is the measurement of the studied features, either clinical, of laboratory or cabinet. A measurement must have two fundamental characteristics, for it to be considered as scientific: consistency and validity. The first one is centered on the variability of the measurement, which is due to the measuring instrument, to the subject or entity which is measured and to the individual or individuals who carry out the measuring, this is known as intra or interobserver variability, respectively. Validity is the fact of "actually" measuring what we want to measure. Both characteristics of measurement, are often mixed, between them and with other concepts, and this is the reason of not having a clear idea of what is the real meaning. This paper discusses the different terms that have been used for consistency and validity of a measurement. Also it points out how to assess consistency, from the validity, taking into account the measuring scale of the variables and the number of observers. Easy examples are used for the application of different formulas and for the interpretation of the results.

Pediatrics↗
PubMed1991

The history of the International Classification of Diseases.

A major purpose for gathering descriptive statistics is to allow comparisons of data over time and among different places. In the case of public health it has been particularly important to make such comparisons utilising diagnostic information. Without a standard measuring tool which remains fixed for periods of time and which is applied uniformly from place to place, meaningful comparative analyses of diagnostic information would not be possible. The International Classification of Diseases is such a standard tool. This presentation briefly traces the history of the development and revision of various versions of this International Classification of Diseases and presents the background leading to the current activities associated with the Tenth Revision of this important health statistical and epidemiological disease classification.

Cause of Death↗