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Results for “ADRENAL GLAND NEOPLASMS”

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At least 433 records · Page 24Linked to original sources

[Congenital neuroblastoma and placental metastases].

Thus far ten patients with connatal neuroblastoma and metastases in the placenta have been reported. Our patient suffered from neuroblastoma stage IV-S and expired on the first day of life due to hepatic failure from massive metastatic involvement of this organ. Metastases from the placenta into the mother have thus far never occurred, neither in our case nor in any patient reported in the literature.

Adrenal Gland Neoplasms↗

[Morphology of experimental tumors of the sympathetic nervous system].

Morphology of experimental tumours of the sympathetic nervous system in rabbits and hamsters induced by administration of nitrose compounds and the use of modifying factors was studied. The tumours were localized in the mediastinum, retroperitoneal space, adrenals and kidneys. The predominant involvement of the female animals was observed. Histological, histochemical and electron microscopic study of 33 tumours of the sympathetic nervous system was carried out. The tumours were classified as ganglioneuromas, ganglioneuroblastomas and sympathoblastomas by their degree of maturity. The experimental tumours by their structure were similar to the analogous neoplasias of man.

Adrenal Gland Neoplasms↗

[Diagnosis and treatment of recurrent pheochromocytoma].

From 1959 to 1992, 216 patients with pheochromocytoma were treated by complete resection of the tumor in our hospital. Ten patients (4.6%) were found to have recurrent pheochromocytoma 1-21 years after operation. Five patients underwent surgical removal of the tumor and normally lived for 1 to 4 years. In remaining 5 patients malignant change was confirmed. Two patients died of extensive metastasis. One who had a recurrent tumor metastasis in the thoracic vertebra was treated with dibenzyline for 9 years. The remaining 2 patients were treated by 131I-MIBG. To prevent or minimize the incidence of recurrence of pheochromocytoma, we suggest: (1) avoid needle biopsy of the tumor, (2) prevent a rupture of the tumor capsule, (3) ligate the veins around the tumor as early as possible and (4) resect the tumor completely or perform a subtotal or total removal of the involved adrenal gland in unilateral cases.

Adolescent↗

Fine needle aspiration cytology of the kidney, renal pelvis, and adrenal.

Fine needle aspiration biopsy for cytologic evaluation of mass lesions of the kidney, renal pelvis and adrenal is a safe economic and accurate diagnostic procedure. Tumors and inflammatory or degenerative lesions arising from these organs have characteristic cytologic features permitting their correct identification in the majority of cases.

Adrenal Gland Neoplasms↗

Surgical diseases of the adrenal gland.

Abnormal levels of adrenal hormones, or their metabolities, in the urine or blood are found in most patients with surgical diseases of the adrenal gland, including neoplastic and some hyperplastic states. Neuroblastomas and nonfunctioning adrenocortical tumors often present as abdominal masses. Surgery is required for the majority of these disorders, particularly for the malignant tumors.

Adrenal Cortex Neoplasms↗

[Characterization of adrenal gland space-occupying lesions. Can diagnostic imaging replace biopsy?].

This paper describes the diagnostic value of new imaging techniques in characterization of adrenal masses and evaluates the role of adrenal biopsy. For differentiation of benign and malignant adrenal lesions, sensitivities and specificities of 85-100% can be reached by unenhanced computed tomography (CT) methods, chemical shift techniques in magnetic resonance imaging (MRI), delayed enhanced CT techniques, and by evaluation of wash-out curves in contrast-enhanced CT. The diagnostic value of all CT techniques depends on threshold values. The value of dynamic contrast-enhanced MRI is under discussion and should be reevaluated by using delayed enhanced series. Biochemical and scintigraphic methods (NP 59 iodine iodomethyl-norcholesterol and MIBG meta-iodobenzylguanidine scintigrams) are valuable for the diagnosis of functional adrenal masses; however, they do not allow differentiation of benign and malignant tumors. According to excellent results of new imaging techniques in characterization of adrenal masses, the indications for fine-needle aspiration biopsy have already regressed, as have complications associated with this invasive technique.

Adrenal Gland Diseases↗

Pheochromocytoma in dogs: 61 cases (1984-1995).

This report presents the clinical, laboratory, imaging, and pathologic findings in 61 dogs with pheochromocytoma by retrospective evaluation of medical records. Pheochromocytomas were diagnosed by histopathologic examination of tissue specimens in all dogs. Special stains (chromogranin A and synaptophysin) also were used to confirm the chromaffin cell origin of the tumors. Epidemiologic findings were in agreement with previous studies, indicating that pheochromocytomas affect middle-aged to older dogs with no apparent gender or breed predilection. The tumor was considered clinical in 21 dogs (34%), was responsible for abnormalities related to a space-occupying mass in 7 dogs (11%), and was an incidental finding in 35 dogs (57%). The hematologic and biochemical findings were nonspecific. Hypertension was detected in 10 of 23 (43%) dogs tested, but all hypertensive dogs had concurrent diseases that may have contributed to hypertension. Abdominal ultrasonography was the most commonly used imaging procedure, with a mass detected in the region of the adrenal glands in 20 of 40 (50%) dogs examined. In 4 of the 20 dogs (20%), invasion of the caudal vena cava was identified. Surgery was performed in 17 dogs (28%) with immediate death or euthanasia of 5 dogs. Survival after surgery ranged from 1 day to 3.25 years. Pheochromocytomas were locally invasive in 39% of affected dogs and produced metastases in 13% of the cases. Common sites for metastases included regional lymph nodes, liver, lung, kidney, spleen, and bone. A high frequency of concurrent neoplasia (54%), including endocrine neoplasia, was identified.

Adrenal Gland Neoplasms↗

[A case report of Cushing syndrome due to three distinct adenomas of the right adrenal].

A case is presented of a 40 y.o. female with Cushing's syndrome. Her plasma glucocorticoid values were elevated (11-deoxy-cortisol: 3.46 ng/ml, cortisol: 25.6 micrograms/dl and cortisone: 35.7 ng/ml) with loss of diurnal variation. Urine 17-OHCS value failed to b suppressed by high dose dexamethasone and was unchanged after metyrapone administration. Her plasma mineral corticoids and androgens were within normal limits. There were 3 separate tumors in the right adrenal on CT and the left adrenal had no uptake on 131I-adosterol scintigram. We, therefore, diagnosed her illness as Cushing's syndrome due to unilateral multiple adenomas. Gross and histological examination of the right adrenal revealed one compact cell dominant adenoma and two clear cell dominant adenomas. This is the 4th case of Cushing syndrome due to unilateral multiple adrenal adenomas in Japan.

Adenoma↗