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Decrease of trace elements in erythrocytes and plasma after removal of dental amalgam and other metal alloys.

The objective of this study was to determine the concentration changes of 13 elements in erythrocytes and plasma after the removal of dental amalgam and other metal alloys. Blood samples from 250 patients were collected, separated into erythrocytes and plasma, and analyzed by inductively coupled plasma-mass spectrometry. The 250 patients were divided into 3 groups (Negative, Zero, and Positive) depending on their estimation of quality of life in an earlier study. Magnesium in plasma, selenium and mercury in plasma, and erythrocytes showed decreased concentrations after amalgam removal in all groups (p < 0.05). Titanium in plasma, copper in plasma, and erythrocytes and zinc in plasma exhibited decreased concentrations after amalgam removal in the Negative and Positive groups (p < 0.05). Silver in plasma and gold in erythrocytes decreased in the Zero and Positive groups after amalgam removal (p < 0.05). Copper in erythrocytes and silver and gold in plasma showed higher concentrations after amalgam removal in the Negative compared to the Positive group (p < 0.05), suggesting that patients in the Negative group excrete metals slowly. Moreover, the cobalt levels in plasma were lowest in the Negative group and only this group showed a significant increase in vitamin B12 levels in blood after amalgam removal.

Adult↗

[Ionogenic liberation of mercury from dental amalgam in waste water and sludge].

Reduction of mercury content in communal waste water and sludge is mandatory. The release rate of Hg from dental amalgam (gamma 2 Lux Alloy) in waste water was determined. The Hg-ionic rate was found to be as low as 0.004% of total mercury content in waste water. In addition, the concentration of Hg (4.39-8.20 mg/kg), Ag (73.35-84.03 mg/kg and Sn (22.51-61.30 mg/kg) in sludge was estimated under anaerobic conditions. Compared with legal limits for drinking water (1 microgram Hg/l) in the F.R.G. mercury loads of dental surgeries are far below threshold levels where toxicological effects are to be expected.

Dental Amalgam↗

Crevice corrosion products of dental amalgam.

The objective of this study was to determine the in vitro corrosion products that resulted from crevice corrosion of low- and high-copper dental amalgams. Specimens were potentiostatically polarized in a chloride-containing electrolyte while set against a PTFE surface to form a crevice. After 16 h, corrosion products were examined by light microscopy, SEM, EDS, and XRD. Analysis showed the presence of three previously reported products [Sn4(OH)6Cl2, SnO, and Cu2O] and a new product, CuCl, which formed on high-copper, gamma 2-free amalgams. Thermodynamic considerations show that CuCl is stable for the reported in vivo potentials of amalgam restorations and the high acidity and high chloride ion concentration associated with crevice corrosion.

Copper↗

Factors affecting estimation of dental amalgam mercury exposure from measurements of mercury vapor levels in intra-oral and expired air.

Several investigators have attempted to assess the extent of mercury exposure from dental amalgam restorations through the use of mercury vapor measurements of intra-oral or expired air. The sampling times and flow rates of the mercury vapor analyzers used in intra-oral measurements are not comparable with physiological inhalation times or flow rates of air through the mouth during inhalation. Analysis of the assumptions and measurement techniques employed in previous attempts to estimate mercury exposure from amalgam restorations shows that adequate compensation had not been made for these measurement parameters. Calculation of the mercury vaporization rates responsible for the mercury vapor concentration values previously reported enabled the daily dose of mercury to be estimated for subjects with various numbers of amalgam restorations. The corrected estimates for daily dose of mercury from amalgam restorations are a factor of sixteen lower than those previously reported.

Air↗