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Results for “FLUORIDE POISONING”

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At least 433 records · Page 24Linked to original sources
PubMed1995

[Relationship between bone fluoride content, pathological change in bone of aborted fetuses and maternal fluoride level].

Relationship between bone fluoride content, pathological change in bone of aborted fetuses and maternal fluoride level was studied in 46 pregnant women and their inducedly-aborted fetuses. Results showed fluoride content in fetal femur averaged 368.2 micrograms/g, and 41.4% of the bone with pathological change. Fluoride levels in maternal urine and amniotic fluid and fluoride content in fetal femur and pathological change in fetal femur appeared a positive correlation between them. Femur fluoride content and pathological change of bone in fetuses born to mothers with mottling teeth were significantly greater than to those without them. Pathological change in fetal femur presented dose-response relationship with their bone fluoride content. When the latter reached greater than 500 micrograms/g, pathological changes occurred in 90% of the bone.

Adult↗
PubMed1994

[Hygienic regulation of yttrium, terbium, ytterbium and lutetium fluorides in the air of the workplace].

The study (experiments on animals and on culture of rats' peritoneal macrophages) covered fluorides of rare-earth metals (REM) assigned to yttrium group--yttrium, terbium, ytterbium, lutetium. Fluorides of REM have low toxicity and cumulativity, induce no local irritation of skin and eyes. Fluorides of yttrium, terbium and lutetium, if administered into stomach, result in specific intoxication (fluorosis). Fluoride of ytterbium did not cause such intoxication. According to short-term tests of cytotoxicity, the foreseeable fibrogenic danger for ytterbium fluoride is moderate, for fluorides of yttrium, terbium and lutetium is mild. The authors recommend to control the level of yttrium, terbium and lutetium fluorides in the air of workplace through the MACs for the fluorides at 2.5 mg/cu m (maximal single concentration) and 0.5 mg/cu m (average shift concentration), the level of ytterbium fluoride as moderate fibrogenic dust at 6 mg/cu m.

Air Pollutants, Occupational↗
PubMed1994

[Histopathologic and bone histomorphometric studies of pigs' phalanges in an endemic fluorosis area].

This paper presents the histopathologic changes and bone histomorphometry of ten pigs' phalanges in an endemic fluorosis area. Ten pigs from nonendemic area served as control. Results showed that the fluoride contents of blood, urine and bone were markedly increased and the calcium contents of blood were markedly decreased in endemic pigs than those in nonendemic ones. Histopathologic and bone morphometric studies of the phalangeal bones of pigs from endemic area indicate that osteoporosis is the predominant change.

Animals↗
PubMed1994

Skeletal fluorosis with neurological complications.

A case of skeletal fluorosis with spinal cord compression from Kekirawa following consumption of water with high fluoride content for about 20 years is described. The observations of other workers (4,5) and the present case report show that more extensive field studies among vulnerable populations is indicated in this region. The need to search for a cost effective method of defluoridation of water is stressed.

Adult↗
PubMed1993

Evolution of fluoride concentrations in cattle and grass following a volcanic eruption.

This study determined fluoride concentrations of forage, water and bovine serum 2-y after the cessation of a volcanic eruption. Three farms within the polluted area were selected, and water and green grass were collected from April 1990 to February 1992. Samples of hay were collected twice from each farm. Five cows exposed during the 13-mo eruption and 6 young bulls not exposed during the volcanic eruption had blood collected monthly or bimonthly. Serum fluoride concentrations and alkaline phosphatase activities were determined and dental conditions observed in all animals. Grass fluoride remained low except during spring of the second year; high fluoride was in the hay. Serum fluoride of the cows remained near acceptable reference values, although some cows had higher values; serum fluoride of the bulls markedly increased during the spring of the second year. Severe incisor attrition occurred in the cows, while the young bulls had less severely eroded teeth.

Air Pollutants↗
PubMedDate not supplied

Fluoride: safety issues.

Fluoride has been used widely in dentistry to prevent dental caries. While there is little doubt regarding its efficacy, the safety of fluoride has been a controversial issue. Abundant scientific data accumulated over the years have demonstrated that other than dental fluorosis, there are no known adverse effects of long-term fluoride ingestion for caries prevention. However, the risk of an overdose is real, and it can result in serious acute toxicity, even death. Understanding potential risks and taking cautions can virtually eliminate the acute adverse effects of fluoride. These potential risks need to be recognized in order to take full advantage of fluoride's benefits.

Alaska↗
PubMed1996

Acute fluoride ingestion: recognition and management.

Occasionally, the Oral Health Division of the Indiana State Department of Health receives inquiries regarding diagnosis and treatment of acute fluoride ingestion. Because a wide variety of fluoride preparations are available in the dental setting and over the counter, excessive ingestion of fluoride can occur if these products are not used properly. The following article is meant to be a quick and easy guide in the recognition and management of instances of acute fluoride ingestion.

Acute Disease↗