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[Diagnosis of varices in liver cirrhosis: duplex ultrasound versus gastroscopy].

This study assesses the usefulness of duplex sonography in the diagnosis of oesophageal varices. 32 patients with liver cirrhosis were studied by endoscopy and duplex sonography. There was an excellent correlation in the case of the medium-sized and large-sized varices. Only small varices could not be detected by duplex sonography. On the other hand, 3 large-sized paraoesophageal varices, which were not identified by endoscopy, were easily seen by duplex sonography. The sensitivity of duplex sonography was between 0.8 and 0.9, the accuracy between 0.93 and 0.96.

Adult↗

Cap-fitted gastroscopy improves visualization and targeting of lesions.

BACKGROUND: Difficulty with visualization and targeting of lesions to obtain biopsy specimens or for endoscopic treatment during diagnostic and therapeutic EGD may be due to a tangential approach, endoscope tip instability, or close proximity to the lesion resulting in a "red-out." Cap-fitted EGD (CF-EGD) adds a "tactile" dimension and enhances visualization and targeting of lesions by allowing manipulation of tangential sites to a more "en-face" approach, thereby improving tip stability and maintaining close apposition to the lesion without losing the endoscopic view. MATERIALS AND METHODS: A recycled transparent cap from a multiband variceal ligator was evaluated during EGD. Where lesions were deemed to be suboptimally visualized or targeted, CF-EGD was performed during the same procedure. Nineteen patients had CF-EGD after conventional EGD. RESULTS: Lesions were located in the duodenal bulb (7), apex of the bulb (5), descending duodenum (1), pylorus (1), posterior gastric wall (3), incisura (1), cardia (1), and afferent limb (Billroth II) (2). Diagnoses were duodenal ulcer (7), duodenal varix (1), gastric metaplasia (1), duodenal Crohn's disease (1), duodenal polyp (3), gastric ulcer (3), antral cancer (1), gastric polyp (1), and anastomotic ulcer (2). Targeted biopsy specimens were obtained in 7, bleeding ulcers treated in 4 (3 duodenal ulcer, 1 anastomotic), and a duodenal polyp (2.5 cm diameter) was removed in 1. CONCLUSIONS: This adaptation of a recycled transparent cap is simple, safe, and effective and improves visualization and targeting of lesions.

Adult↗

Computed tomography gastrography with volume-rendering technique: correlation with double-contrast barium study and conventional gastroscopy.

The volume-rendering technique uses computed tomography data to produce simulated images of conventional barium and endoscopic studies of the stomach. Various gastric lesions are detected on volume-rendered images, and submucosal tumors are easily differentiated from mucosal lesions by means of the overlying bridging fold. Lesions that are only manifested by a change of mucosal color (early gastric cancer type 2b) or a loss of mucosal detail (gastritis) are difficult to detect from volume-rendered images, however. In cases of gastric neoplasm and varix, both the extraluminal pathologies of the lesion and the relation between the intraluminal and extraluminal components can be evaluated simultaneously.

Adenomatous Polyps↗

Sedation for gastroscopy: a comparative study of midazolam and Diazemuls in patients with and without cirrhosis.

A double-blind controlled study comparing the effects of intravenous Diazemuls (0.15 mg kg-1) with midazolam (0.07 mg kg-1) in patients with normal liver function and with cirrhosis and portal hypertension is described. The clinical effect of the two drugs was assessed by serial tests of psychomotor function before and at varying intervals after administration. Using this dosage regime, midazolam caused significantly greater impairment in psychomotor function in both cirrhotic and non cirrhotic subjects, and the time taken for recovery of normal function was also significantly prolonged. Patients with cirrhosis showed a significantly prolonged recovery time following administration of either benzodiazepine compared with the controls. Administration of midazolam in a lower dose might reduce the degree of sedation and shorten the recovery time, but this could also lead to a loss of some of the amnesic effect. Caution is recommended in the administration of benzodiazepines to patients with cirrhosis.

Adult↗