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At least 433 records · Page 24Linked to original sources

Sequential atrioventricular pacing as a stress test. Evaluation of left ventricular function in second-degree AV heart block developing during atrial pacing.

Advanced or second-degree atrioventricular (AV) heart block pre-existing or developing during atrial pacing (AP) at low heart rates of smaller than 130 per minute, limits the value of AP to stress the left ventricle. When Wenkebach type AV block is present, the heart rate can be increased by administration of atropine before atrial pacing or by right ventricular pacing. Atropine, however, occasionally may cause serious supraventricular or ventricular arrhythmias, and high rate right ventricular pacing is not tolerated by many patients with left ventricular dysfunction because of the absence of the atrial contribution. Twenty-eight out of 101 patients with angina pectoris (27.7 percent) developed second degree AV heart block during atrial pacing studies performed for evaluation of left ventricular function. In 8 of the 28 patients, sequential AV pacing (SP) was performed successfully, with the heart rate being increased to 150-167 per minute. In 4 of the 8 patients, left ventricular dysnfunction was demonstrated during and immediately after SP. Typical angina pectoris developed in two of the four patients during SP, one of whom proved to have normal coronary arteriogram. Sequential AV pacing is an alternative method to increase the heart rate for the purpose of stressing the left ventricle when advanced degree or second-degree AV heart block pre-exists or develops during right atrial pacing. In some patients the method of SP might be preferable to administration of atropine or to ventricular pacing.

Adult↗

Sustained-release diltiazem in patients with effort angina and severe coronary artery sclerosis.

Two case histories are presented. Patient 1 was an agricultural worker, aged 63 years, whose attacks of chest pain, diagnosed as effort angina, were relieved by sublingual nitroglycerin. An exercise test revealed ST segment depression of 2 mV in lead V5 of the electrocardiogram. Coronary arteriography disclosed 99% stenosis with delay in segments 7 and 14, 90% stenosis in segment 10, and 25% stenosis in segment 1. Treatment with 100 mg of sustained-release diltiazem relieved some of the symptoms; when the dose was increased to 200 mg daily, no further chest pains were experienced. Patient 2 was a restaurant owner, aged 61 years, who reported attacks of chest pain during physical work. An exercise test revealed ST segment depression of 2 mV in lead aVF; coronary arteriography showed 99% stenosis in segment 7, 75% stenosis in segment 9, and 50% stenosis in segment 10. No attacks of chest pain were experienced after treatment with 200 mg of sustained-release diltiazem daily. Blood pressure, heart rate, and the rate-pressure product fell in both patients after diltiazem treatment.

Angina Pectoris↗

Effect of exercise on left-ventricular systolic time intervals in patients with coronary heart disease.

Left-ventricular systolic time intervals measured at rest and after submaximal exercise were analysed in 156 patients with positive exercise test results and in 219 healthy volunteers with negative exercise test results. The patients were suffering with high probability, from coronary heart disease. The healthy subjects as well as the patients were divided into five groups on the basis of the submaximal exercise loads tolerated by them. Load of 30 W was taken as starting point. At rest, the patients had shorter ejection times (LVET) and total electromechanical systolic times (QS2), and longer preejection periods (PEP) and isovolumetric contraction times (ICT), than the healthy subjects. The PEP/LVET ratio for the patients was higher than that for the healthy subjects. In groups of the same tolerance to work, exercise induced less pronounced decreases in PEP and PEP/LVET values and more pronounced decreases in QS2 and LVET values in the patients than in the healthy subjects.

Adult↗

[Use of the hyperventilation test in patients with various forms of angina].

The pulmonary hyperventilation (HV) test was carried out in 31 coronary patients with stable angina and 11 patients with spontaneous (angiospastic) angina. The test results were compared to those obtained with bicycle ergometry (BE), 24-hour ECG monitoring and selective angiography. The HV test was positive in 7 of 24 patients with positive BE results. The BE and 24-hour ECG monitoring were superior to the HV test in terms of sensitivity. Positive HV tests were more common in spontaneous angina. It is suggested that the HV test can be used for diagnosis and medication efficiency control in coronary patients.

Adult↗