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At least 433 records · Page 24Linked to original sources

Surgical treatment of T1-T2 glottic carcinomas.

Transoral laser surgery (TLS) is a safe, time and cost-effective method of treatment for early stage glottic squamous cell carcinoma. This technique is more controversial in case of local extension to other subsite or in case of limited mobility.

Carcinoma, Squamous Cell↗

CT findings in laryngeal chondroradionecrosis.

The progressive CT features of the laryngeal framework and soft tissues in a case of laryngeal chondroradionecrosis are described. The differential diagnosis with tumor recurrence was at first uneasy, but the protracted history evolution of the tissue changes on CT eventually allowed correct diagnosis.

Aged↗

Surgical approach to organ preservation in the treatment of cancer of the larynx.

Nonsurgical approaches to preservation of the larynx in the treatment of laryngeal carcinoma include either radiation alone or chemotherapy and radiation in combination. In light of the common use of total laryngectomy, these nonsurgical approaches have often been referred to as "organ-preservation" strategies. Within the context of this old paradigm, clinicians viewed surgery as offering the patient local control, with the caveat that the price would either be the loss of the larynx or the creation of a disability in swallowing or speech. Over the last 10 years, there has been a renaissance in the surgical approaches to laryngeal preservation, as evident in the surgical literature. A new paradigm has emerged in which both the surgical and nonsurgical approaches have equal value in laryngeal organ preservation. Today, a broad spectrum of surgical organ-preservation techniques are available that result in excellent oncologic outcomes as well as excellent and consistent functional outcomes in terms of speech and swallowing. The aim of this article is to present the options for organ-preservation surgery for laryngeal cancer.

Carcinoma↗

Limitations of conservation surgery in carcinoma involving the arytenoid.

The various types of conservation surgery for laryngeal cancer can be systematized in one entity and be classified into four types of "laryngoplasty." Laryngeal cancer involving the arytenoid is thought to be amenable to laryngoplasty type 3. The indication and the procedures of hemilaryngectomy B, subtotal laryngectomy, and subtotal laryngopharyngectomy are described. The therapeutic results of these operations were better than that of total laryngectomy. Tumors involving both sides of the arytenoid portion rule out conservation surgery. They should be treated by the operations of laryngoplasty type 4, which means total laryngectomy and laryngeal reconstruction.

Aged↗

Anterior commissure cancer--a clinical and laboratory study of 39 cases.

Of 13 anterior commissure cancers treated by radiation therapy and reported in 1970, eight had residual or recurrent cancer at the primary site and required total laryngectomy. All but one of the 13 had been treated prior to 1958 by Orthovoltage radiation. A total of 19 patients with anterior commissure lesions were treated at the Yale-New Haven Hospital using a 2MEV Van de Graaf generator between mid 1958 when this supervoltage source first became available and December 1971. None was lost to follow-up and thus all are available for evaluation after more than two years. Results in this group have been compared with 20 glottic carcinomas with involvement of the anterior commissure treated surgically during the same period of time. Thirteen of the resulting 20 surgical specimens have been studied by serial section.

Epiglottis↗

The applied anatomy of the anterior commissure and subglottis.

The applied anatomy of the subglottis and anterior commissure is discussed and an attempt made to correlate the histological anatomy with that clinically accessible. It is suggested that although the undersurface of the vocal fold is classified as part of the glottis by the 1972 UICC and AJC staging system, it should be considered as the roof of the subglottis. The anterior commissure, which is probably a small site within the glottis rather than a true area, is histologically difficult to separate from the anterior subglottis. The characteristic microvasculature of the anterior commissure is presented as being possibly relevant to the mode of spread of tumors at this site.

Epithelium↗

[Comparison of long-term carcinologic results between radical and conservative cervical surgery].

The aim of this research was to compare isolated ganglionic development in patients treated surgically for cancer of the larynx. This research included the cases of 232 patients operated on for laryngeal cancer and who underwent either total laryngectomy with or without conservation of the cricoid, or supra-glottal laryngectomy, or sub-glottal pharyngectomy. For the treatment of the ganglionic areas, there are six possibilities: --cobalt used in isolation; --uni- or bi-lateral cellulo-adenectomy; --uni- or bi-lateral curettage (a month apart); --curettage on one side, cellulo-adenectomy on the other. The results obtained were particularly significant as far as the N0 and regrouped N1 were concerned. The rate of ganglionic recurrence was 25 p. 100 for the N0 treated with cobalt and 6,5 p. 100 when surgery was carried out (cellulo-adenectomy or curettage). Also, curettage seems in N + cases to give better results : 26 p. 100 recurrence in cases of cellulo-adenectomy for N0-N1 and 4 p. 100 only in cases of curettage. These results appear to justify on the spot histological examination followed by curettage in N + cases.

Cobalt Radioisotopes↗

[Cricohyoidoepiglottopexy: a report of 21 cases].

OBJECTIVE: To assess the indications, function preserving and long term results of cricohyoidoepiglottopexy (CHEP) in the treatment of laryngeal carcinoma. METHOD: Twenty-one patients were underwent this procedure during the period from 1993 to 1999 in our department. There were 20 glottic cancers (7 T1N0M0, 10 T2N0M0, 3 T3N0M0) and 1 supraglottic type (T2N1M0) according to the 1997 UICC system. In these cases, 15 were the aged over 60 years. RESULT: First decannulation rate was 95.24%, and majority completed in 28 days post-operation. No patient was with cannula all his life. All cases could finally take food by mouth without aspiration. Speech was also satisfactory. The overall 3-year and 5-year survival rates were 87.50% and 75.00% respectively. No patient experienced local recurrence. CONCLUSION: This procedure is presented as a useful alternative to partial vertical laryngectomy and total laryngectomy in select cases of laryngeal carcinoma.

Adult↗

[Stage T1 malignant tumors of the arythenoid. Analysis of a series of 26 cases].

26 malignant tumours of the arytenoid classified as T1 according to the UICC 1987, were treated in the ENT and Cervico-Facial Surgery wards to Hospital Laennec between 1961 and 1990. The natural history of these lesions, locoregional efficiency of the different treatments used, the part played by chemotherapy, survival, causes of death and therapeutic modalities used as a last measure, have been analysed. The frequency of tumours with neuroendocrine has been emphasized. Such a diagnosis should be questioned when the initial biopsy does not diagnose a well differentiated epidermoid carcinoma. The use of argyrophil colouring in order to find neurosecretive granules helps in carrying out the diagnosis. The treatment of tumours, classed T1 N0 M0, of the arytenoid, is based on partial, laryngeal surgery associated with a preventive, jugulo-carotidian-ipsilateral ganglionary intervention.

Actuarial Analysis↗