Chromosome 7q: where autism meets language disorder?
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This study examines phonological awareness in a group of 10 dyslexic children, compared with two groups of children (a reading-equivalent control group and a group of beginning readers). Five of the dyslexic children exhibited an early speech-language impairement, and five others were not language-impaired. The experimental design consisted of a set of 10 tasks involving sensitivity to phonological strings, phonetic identification, and phoneme segmentation and manipulation. The major findings reveal that (a) the two subgroups of dyslexic children exhibit a metalinguistic impairment and (b) dyslexic children with speech-language impairment exhibit (besides metalinguistic impairment) a deficit concerning early precursors of the phonological awareness (rhyme and syllables). These findings provide additional support for including speech-language impairment as an operational criterion within the heterogeneous group of dyslexic children.
The infarction in the territory of the anterior choroidal artery may induce a sensory motor impairment and neuropsychological symptoms close to those observed in some thalamic lesions. In a right handed man with a left sided infarction, language disturbances and constructional apraxia were observed. Cerebral blood flow measurements were performed 4 days after the stroke with the 133Xenon inhalation method. A decrease of mean hemispheric values was observed on both sides but more so on the left hemisphere, in the left frontoparietal regions. 98 days after the stroke language and constructional apraxia have partially improved. We have drawn a parallel between blood flow variations and neuropsychological signs. The cortical deafferentation caused by the interruption of the thalamo-cortical projections may explain the focalized decrease in cerebral blood flow values in the left hemisphere.
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Child neurologists are often asked to evaluate young children who have failed to develop speech despite adequate hearing and skills for non-verbal tasks. At our center, in addition to a standard neurologic evaluation, hearing test, and EEG, we obtain videotape recordings of the child and his mother in play interaction. These observations enable us to assess the child's non-verbal communicative abilities, his affect, his ability to utilize toys symbolically and creatively, and his attention span. Approximately 20 preschool children who were non-verbal or had very limited speech at entry into our study are being followed longitudinally. Readily observable aspects of language and behavior were scored by reviewed the serial videotapes obtained over a 2-year period. Predictors of outcome that do not require detailed linguistic analysis of the child's utterances are tentatively identified and discussed.
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