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At least 433 records · Page 24Linked to original sources
PubMed2002

A solitary huge neurofibroma of the soft palate.

Neurofibroma of the soft palate, an extremely rare tumour, is probably not yet reported in the literature. We report the first case of an isolated neurofibroma of the soft palate not associated with von Recklinghausen's disease (VRD), which is also, probably, the first reported case of neurofibroma of the soft palate. The tumour was completely removed from the soft palate after performing tracheostomy, necessitated due to difficulties in intubation.

Female↗
PubMed1975

The value of Gallium67 scanning in the evaluation of head and neck malignancy.

Gallium (67Ga) citrate is a scanning agent that has been shown to have a differential uptake in a variety of malignancies. Investigation of the usefulness of 67Ga scanning patients with proven squamous cell carcinoma of the head and neck region is now in progress. These patients have a 67Ga total body scan as part of the pre-treatment evaluation. The accuracy of the procedure is then judged by correlation with clinical and surgical findings. The results in 25 patients show that a clearly positive uptake occurs in 60 percent in the region of the primary. Uptake in metastatic disease in lymph nodes is much less, occurring in 6 of 18 sides of the neck. In one case, where clinical examination was considered to be negative, the gallium scan was positive and subsequently proven to be correct by histological examination of the surgical specimen. The various difficulties encountered in interpreting gallium scans in the head and neck region are described. It is felt that by improved patient selection and special techniques the yield of positive cases can be improved and unsuspected extension of malignancy demonstrated.

Carcinoma, Squamous Cell↗
PubMed1991

Surgical pathology of cancer of the oral cavity and oropharynx.

A study was designed to determine the influence of certain surgical pathologic findings on tumor spread and survival in patients with cancer of the oral cavity and oropharynx. All patients with the histopathological diagnosis of carcinoma of the oral cavity or oropharynx from 1955 to 1983 were included in the study. Using the Head and Neck Tumor Registry of the department of otolaryngology of the Washington University School of Medicine, information was obtained regarding preoperative evaluation, staging, classification, diagnosis, treatment, surgical pathology parameters, and outcome results. The patient populations consisted of 545 patients with oral cavity cancer and 224 patients with oropharynx cancer, all of whom were eligible for 3-year follow-up. Information from a retrospective analysis of the pretreatment examination records regarding site and size of the primary tumor and neck dissection, and specific treatment, and from surgical pathology reports regarding site, size, tumor spread and resection margins, was correlated with treatment outcome. The database file was analyzed using dbase III and its companion program Framework, and SAS PC (Statistical Analysis Systems for personal computers).

Cause of Death↗
PubMed1994

Three-dimensional models for head and neck tumor treatment planning.

The authors have evaluated two types of practical maxillofacial model systems useful to the head and neck surgeon:1. plastic mandibular model generated by three-dimensional computerized tomography (CT) reconstruction, and 2. dental impression model of the maxilla. The first model is expensive and technology intensive; the second is simple but limited. Both three-dimensional models offer several advantages: 1. they provide segmental mandibular relationships that are not known because of oncologic restrictions or previous surgery; 2. they allow preoperative reconstructive planning including prosthesis fabrication and visualization of tumor extent not obvious by two dimensional imaging; and 3. they provide a permanent record for future needs or reconstructions. The disadvantages include cost, time, and possible inaccuracies secondary to image artifacts. We find both models to be of significant practical value in selected head and neck tumor patients.

Adenocarcinoma↗
PubMed2000

Lipoma of the cleft soft palate: a case report of a rare congenital anomaly.

OBJECTIVE: Congenital tumors of the oral cavity are extremely uncommon. The teratoid tumors (epiganthi, dermoid, and hairy polyps) account for almost all of the reported cases and are not infrequently associated with cleft of the soft palate. Of the remaining tumors in the pediatric cleft palate population, infantile lipoma of the oral cavity is exceedingly rare. A case of a congenital lipoma associated with a cleft of the soft palate is presented. The review of the literature, the description of the lesion, the diagnosis, and the management of this finding are outlined.

Cleft Palate↗
PubMed2003

Alternative impression technique for a speech-aid prosthesis.

OBJECTIVE: Prosthetic treatment for speech disorders attributable to surgically acquired soft palate defects are introduced. CASE: A patient who underwent soft palate resection for cancer is presented. The resected portion of the soft palate was confined to the posterior segments. A prosthesis with a speech bulb was adapted to the patient. CONCLUSION: Excellent restoration of speech and improvement of velopharyngeal function was achieved following placement of the special prosthesis.

Adult↗
PubMed1998

Evidence for polymorphism of Merkel cells in the adult human oral mucosa.

We recently reported that Merkel cells in the normal palatine mucosa of adult rodents are highly polymorphic. In order to ascertain whether or not this polymorphism is also evident in the human oral mucosa, palatine mucosae from cadavers without oral diseases and perilesional palatine mucosae of patients with pleomorphic adenoma were examined by immunohistochemistry using an antibody against cytokeratin 20. Findings showed that Merkel cells in the human normal palatine mucosa were polymorphic, and a number of irregular-shaped Merkel cells (dendritic Merkel cells) with apparent cytoplasmic projections were present among typical oval to round Merkel cells. The mucosa usually contained a small number of oval to round Merkel cells residing in ectopic places such as prickle and granular cell layers. On the other hand, the slightly inflamed perilesional palatine mucosa contained an increased incidence of dendritic Merkel cells. Ectopic Merkel cells were rare in the perilesional palatine mucosa. Characteristics of dendritic Merkel cells were examined using specimens from perilesional palatine mucosae by means of immunohistochemistry and electron microscopy. It was shown that every dendritic Merkel cell and most roundish Merkel cells in the perilesional mucosa lacked innervation. Electron microscopy suggested that dendritic Merkel cells release secretory granules from the tip of the cytoplasmic process and the basal cytoplasm towards the lamina propria mucosae, in a manner resembling the case of similar cells in rodents.

Adenoma↗