Adaptation of intravenous procaine to industrial medicine.
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Acclimatization↗
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Results for “PROCAINE AND COMPOUNDS”
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The effects of thiopental sodium, chloroform, and diethyl ether on the metabolism and toxicity of procaine.
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Barbital↗
[Combination of mel B and novocaine].
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Honey↗
[Mixture of mel B and novocaine in solution in dimethylacetamide].
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Acetamides↗
[Mistakes and dangers in novocain injection].
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Anesthesia↗
Treatment of backaches by infiltration of anesthetic oils.
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Anesthetics↗
[Novocaine treatment of diseases of the peripheral arteries].
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Arteries↗
[Action of novocaine on traumatic and neurovegetative pain].
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Pain↗
[Endarterial penicillin-novocain therapy in acute inflammation of the extremities].
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Extremities↗
[Novocain perfusion in postoperative complications of neurosurgery].
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Brain↗
[Intracarotid novocaine emergency treatment of an epileptic seizure].
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Emergency Treatment↗
[Mechanism of action of intravenous novocain].
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Anesthesia↗
[Treatment of chronic adnexitis by penicillin-novocain infiltrations].
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Female↗
Procaine--an occupational hazard; its prevention and therapy.
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Communicable Diseases↗
[Pharmacological analysis of the bioelectric activity of the Pacinian corpuscles].
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Acetylcholine↗
[Excitation contraction mechanism of the guinea pig bladder muscle].
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Animals↗
Rotifer neuropharmacology--II. Synergistic effect of acetylcholine on local anesthetic activity in Brachionus calyciflorus (Rotifera, Aschelminthes).
A number of compounds showing general anesthetic action in the rotifer Brachionus calyciflorus were investigated in the presence of acetylcholine. Non-ionizing anesthetics, including tricaine, showed no interaction with acetylcholine. However, highly ionized compounds like the local anesthetics procaine and lidocaine, the muscarinic blocker and local anesthetic atropine, and the beta-adrenergic blocker propranolol showed a synergistic effect with acetylcholine. ACh increased the general anesthetic effect of these compounds in a statistically highly significant dose-dependent fashion. To account for the mechanism of this unusual and novel effect it is proposed that these compounds interact with the anesthetic binding site of the rotifer cholinoceptor ionophore in the open state. It is also proposed that non-ionizing compounds have a general membrane effect only. In addition to anesthesia, atropine and propranolol cause foot paralysis in B. calyciflorus. This other novel effect is also enhanced by acetylcholine as well as decamethonium, a neuromuscular blocker.
Acetylcholine↗