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PubMed1992

Census adjustment and the distribution of federal spending.

In 1989, programs that use population counts to determine the distribution of their funds transferred $236 per capita to state and local governments. If the 1990 census were adjusted to reflect undercounting, about 40% of state and local governments would receive increased grants averaging $56 per miscounted person; other jurisdictions would lose an almost equal amount of grant money. The surprisingly small reallocations arise because 1) total funds allocated by population are essentially fixed; 2) allocations depend on other factors in addition to population; and 3) programs vary as to whether they allocate funds in direct or inverse proportion to population.

Community Health Services↗
PubMed1995

Bangladesh. Population education programme reviewed.

The UNFPA (UN Population Fund)-funded population education program was reviewed last November 1994 in order to identify the emerging needs and requirements as well as chart the future directions of the program. The review was undertaken with the assistance of the CST SAWA Adviser on Population Education, Dr. D.M. de Rebello. Comprehensive literature review, and intensive discussions with government functionaries, educationists, teachers, students, UNFPA country director and staff and concerned officials of the World Bank and other UN agencies involved in the program served as the modalities for the review. The review looked into the current status of the school education sector and assessed the present progress of the population education program vis-a-vis its objectives and achievements. It also analyzed the issues and constraints in relation to institutionalization of the program, capacity building and integration of population education in curriculum and textbooks. Among the many recommendations, the review proposed further building up of national capacities at various levels; development of teaching/learning materials and textbooks for the new sectors; and intensification of good quality teacher education. Institutionalization of population education in the formal school system up to grade 12 and in technical and vocational education as well as the madrasah system and the introduction of population education in the Mass Non-formal Education Program were also proposed.

Asia↗
PubMed1994

Use of pap-smears in a population without a mass screening program.

STUDY OBJECTIVE: To analyze the use of Pap-smears in a population where a screening program was not offered. DESIGN: Retrospective analysis of pathology registry data on women resident in two counties of Norway. SETTING: Evaluation of opportunistic screening by age and year of birth. Proportion of population tested during successive 3-year periods. MATERIAL: 353,665 smears from 88,048 women examined since 1973. For this purpose we concentrated on 257,951 smears from 77,431 women examined during the period 1981-90. RESULTS: Between 62 and 67% of women examined during each 3-year period were 20-39 years old, 14-16% were 50-69 years of age. Throughout the ten-year period the frequency of Pap-smear testing of women over 60 and under 20 increased slightly whereas it decreased for women 20-39 years old. Follow-up of positive or atypical smears comprised about 25% of all smears. The highest proportion of follow-ups was found among women 30-49 years old. About one third of women aged 20-59 years had more than one smear taken in a 3-year period, follow-up smears excluded. CONCLUSION: More than half of the women aged 50 and above have no smears or smears less than one every third year. This proportion increases with age. The use and distribution of smears by age is still far from the situation expected in an organized screening program although a slight amelioration was observed through the study period.

Adult↗
PubMed2002

Adult and embryonic blood and endothelium derive from distinct precursor populations which are differentially programmed by BMP in Xenopus.

Blood and blood vessels develop in close association in vertebrate embryos and loss-of-function mutations suggest common genetic regulation. By the criteria of co-expression of blood and endothelial genes, and lineage tracing of progeny, we locate two distinct populations of progenitors for blood and endothelial cells in developing Xenopus embryos. The first population is located immediately posterior to the cement gland during neurula stages and gives rise to embryonic blood and vitelline veins in the anterior ventral blood island (aVBI), and to the endocardium of the heart. The second population resides in the dorsal lateral plate mesoderm, and contains precursors of adult blood stem cells and the major vessels. Both populations differentiate into endothelial cells in situ but migrate to new locations to differentiate into blood, suggesting that their micro-environments are unsuitable for haematopoietic differentiation. Both require BMP for their formation, even the Spemann organiser-derived aVBI, but individual genes are affected differentially. Thus, in the embryonic population, expression of the blood genes, SCL and GATA2, depend on BMP signalling while expression of the endothelial gene, Xfli1, does not. By contrast, Xfli1 expression in the adult, DLP population does require BMP. These results indicate that both adult and the anterior component of embryonic blood in Xenopus embryos derive from populations of progenitors that also give rise to endothelial cells. However, the two populations give rise to distinct regions of the vasculature and are programmed differentially by BMP.

Animals↗
PubMedDate not supplied

Best practices for an integrated population health management (PHM) program.

Large employers are beginning to create much more robust and potentially effective systems of integrated health management interventions. This organization-wide activity is referred to as a "Population Health Management" (PHM) approach. Best practices are also beginning to emerge in this area, and a number of technical developments are helping shape the patterns of response from innovative employers. This initiative is rapidly emerging as a critical part of overall business and health care strategy.

Behavior Therapy↗
PubMed1999

Patterns of programmed cell death in populations of developing spinal motoneurons in chicken, mouse, and rat.

During embryonic development, approximately one-half of the spinal motoneurons initially generated are lost during a wave of programmed cell death (PCD). Classical studies in this system laid the basis of much work on the role and control of neuronal cell death during development. However, we have little information concerning the timing of cell death in motoneuron pools at different rostrocaudal levels, especially in rodents. We developed a novel protocol for whole-mount TUNEL labeling that allows apoptotic nuclei to be visualized in whole-mount preparations of embryonic spinal cord; double labeling with antibodies to Islet 1/2 showed that nearly all TUNEL-positive cells were motoneurons. In chicken and mouse embryos, the density of TUNEL-positive nuclei was specifically increased following target ablation. The pattern of naturally occurring motoneuron PCD was studied in spinal cords from different species and ages: chick (E4.5-E9.0), mouse (E11.5-E15.5), and rat (E13.5-E16. 5). In all species, motoneuron PCD is first apparent at cervical levels and last at sacral levels. However, motoneuron PCD does not follow a strict rostrocaudal sequence. Following cervical motoneuron PCD, TUNEL profiles are first observed at lumbar levels in chick but at thoracic levels in rat. At a given rostrocaudal level, medial motoneurons tend to die before lateral populations, but here too there are exceptions. Motoneuron cell death is thus regulated in a highly stereotyped manner during development of vertebrate spinal cord. Our technique will provide a basis for the monitoring even localized changes in this pattern.

Animals↗
PubMedDate not supplied

Wealth from Health: an incentive program for disease and population management: a 12-year project.

The future of healthcare is linked with its ability to face the challenges of consumerism. Disease and population management will represent the dominant style of healthcare delivery in the future. This article describes the Wealth from Health programs which utilize current and future technologies to help the healthcare system become a leader in healthcare delivery and to assist many communities at an affordable cost.

Asthma↗
PubMed1985

Determining school programming needs of special population groups: a study of asthmatic children.

A study of the 4,382 children in the New Milford (Connecticut) Public School System was conducted to determine if upper respiratory conditions and other health problems may be related to school performance. Seven percent of the 4,036 respondents were found to be asthmatic. Correlations of school-related factors for 61 of 286 students who had high absenteeism did not appear to be dependent upon asthma for any identified health problem. As absenteeism increased, student grades decreased. Achievement testing in math and reading was related positively to IQ and appeared to be unaffected by absenteeism from school. On the basis of this study, special education programming was not recommended for the target population; however, parents and school personnel are much more aware of physical, emotional, and mental health problems and their possible implications for school performance.

Absenteeism↗
PubMed1997

Diagnostic interpretation of electrocardiograms in population-based research: computer program research physicians, or cardiologists?

We assessed the performance of diagnostic electrocardiogram (ECG) interpretation by the computer program MEANS and by research physicians, compared to cardiologists, in a physician-based study. To establish a strategy for ECG interpretation in health surveys, we also studied the diagnostic capacity of three scenarios: use of the computer program alone (A), computer program and cardiologist (B), and computer program, research physician, and cardiologist (C). A stratified random sample of 381 ECGs was drawn from ECGs collected in the Rotterdam Study (n = 3057), which were interpreted both by a trained research physician using a form for structured clinical evaluation and by MEANS. All ECGs were interpreted independently by two cardiologists; if they disagreed (n = 175) the ECG was judged by a third cardiologist. Five ECG diagnoses were considered: anterior and inferior myocardial infarction (MI), left and right bundle branch block (LBBB and RBBB), and left ventricular hypertrophy (LVH). Overall, sensitivities and specificities of MEANS and the research physicians were high. The sensitivity of MEANS ranged from 73.8% to 92.9% and of the research physician ranged from 71.8% to 96.9%. The specificity of MEANS ranged from 97.5% to 99.8% and of the research physician from 96.3% to 99.6%. To diagnose LVH, LBBB, and RBBB, use of the computer program alone gives satisfactory results. Preferably, all positive findings of anterior and inferior MI by the program should be verified by a cardiologist. We conclude that diagnostic ECG interpretation by computer can be very helpful in population-based research, being at least as good as ECG interpretation by a trained research physician, but much more efficient and therefore less expensive.

Bundle-Branch Block↗
PubMed1976

The Post-Mastectomy Rehabilitation Group program. Structure, procedure, and population demography.

Memorial Hospital, New York City, clinical section of the Memorial Sloan-Kettering Cancer Center, has developed a Post-Mastectomy Rehabilitation Group (PMRG) which provides a comprehensive structure program to enable the mastectomy patient to regain functional use of her arm and shoulder on the affected side, and to adapt functionally, psychologically, and emotionally to the loss of her breast and the diagnosis of cancer in the shortest time possible. This first segment of an evaluation of the program outlines the PMRG structure and operating procedures and presents basic demographic data (age, type of mastectomy, preoperative activity status) for 863 of the 1,400 mastectomy patients who attended the program since inception in 1970. Additional reports will focus on the physical and psychologic aspects of recovery and readjustment.

Adult↗
PubMed1995

Maldives. Package on population education for special interest groups developed.

The Population Education Program of the Non-Formal Education Center has developed a package of Population Education for Special Interest Groups comprising a learning package and fieldworker's guide. The learning package is especially developed for teaching population education for out-of-school populations. Special interest groups in Maldives include newly married couples, adolescents, and working youth. Produced under the guidance of UNESCO, Bangkok, the package contains 36 different materials such as posters, charts, leaflets, booklets, stories, and illustrated booklets which may be taught in 36 to 45 periods. The materials deal with eight themes, namely, family size and family welfare, population and resources, delayed marriage and parenthood, responsible parenthood, population-related values and beliefs, women in development, AIDS/STD, and respect for old people. Accompanying the learning package is the fieldworker's guide used to teach the package. It contains individual guides for each of the 36 learning materials. The guide gives the titles of the materials, format, objectives of the materials, messages, target groups, and an overview of the content of each learning materials. The methodologies used for teaching the learning materials include role playing, group discussion, questioning, brainstorming, survey, creative writing, problem-solving and evaluation. The package will be used by fieldworkers to conduct island-based population education courses.

Asia↗
PubMed1979

A computer program for survival comparisons to a standard population.

PROPHAZ is a computer program created for the analysis of survival data using the general proportional hazards model. It was designed specifically for the situation in which the underlying hazard function may be estimated from the mortality experience of a large reference population, but may be used for other problems as well. Input for the program includes the variables of interest as well as the information necessary for estimating the hazard function (demographic and mortality data). Regression coefficients for the variables of interest are obtained iteratively using the Newton-Raphson method. Utilizing large sample asymptotic theory, x2 statistics are derived which may be used to test hypotheses of the form C beta = 0. Input format is completely flexible for the variables of interest as well as the mortality data.

Computers↗
PubMed1996

A microcomputer program for calculating cell population doubling time in vitro and in vivo.

Determination of the doubling time for a population of cells can involve tedious calculations. We have developed computer software for MS-DOS microcomputers to expedite the analysis of tumor cell growth in vitro and in vivo. This program, DOUBLE-TIME, assists in the collection of cell numbers into a database and calculates the doubling time for a population of cells from the plot of cell growth over time. For experiments where tumor mass is measured in vivo, the software collects measurements of tumor size, calculates tumor volume (mass), generates growth curves for tumor volume change over time, and determines the doubling time of the tumor and the mean for multiple tumors. DOUBLE-TIME plots both total and viable cell numbers over time, calculates standard error of the doubling time, and the doubling time for a selected portion of a growth curve. This software also automates the cell counting process with a software-generated cell counter that allows cell counts to be tallied directly into the computer via a mouse.

Animals↗
PubMed1997

Evaluating a primary prevention program in a multicultural population: the importance of representations of back pain.

OBJECTIVE: This study was carried out during 4 years of longitudinal research assessing back pain problems and the impact of a back pain primary prevention program on the employees of a food and non-food chain store. The impact of the teaching program was reevaluated in a secondary analysis, taking into account subjects' prior representations of back pain. METHODS: Subjects were grouped according to their cultural origins and socioprofessional levels. Their representations were assessed by means of open questions before and after the teaching program. RESULTS: The teaching program reinforced pre-existing representations in those participants socioculturally nearest the teachers; it had a weak or even disturbing impact on those furthest removed from the teachers in sociocultural terms. CONCLUSION: The differential impact of the teaching program in this study indicates that participants' prior representation play a role in the outcome of a Back School teaching program. Thus, the participants' representations should be taken into account when designing the program and when assessing participants' suitability for such programs, their adherence, and the outcome.

Back Pain↗
PubMedDate not supplied

Broadening the base of a rare donor program by targeting minority populations.

Some red cell phenotypes are found exclusively in one race and may be of low frequency. Finding compatible blood for patients needing one of these rare types has been extremely difficult. A program was implemented to screen large numbers of donors for blood types found solely in their racial group. Implementation steps included obtaining broad community endorsement of the concept, educating blood service personnel, developing educational materials, enlisting the support of a knowledgeable physician from a minority group, developing a computer program to facilitate selection of donors to be tested, beginning the program and making the necessary adjustments, doing the laboratory testing to identify rare bloods, notifying the rare donors, and maintaining the enthusiasm of the entire blood service for the rare donor screening program. After 7706 black donors were typed, 1 Cr-, 5 Hy-, 24 U-, and 20 Js(b-) persons were found; one U- donor was also Js(b-).

Black People↗