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At least 433 records · Page 24Linked to original sources

Matrix-assisted laser desorption ionization mass spectrometry: a new tool for probing interactions between proteins and metal surfaces. Use in dental implantology.

The fixation in the bone of an artificial titanium tooth root is believed to be initiated by the rapid adsorption of the proteins present in the surgical cavity on the titanium surface. The study of this adsorption should make it possible to predict the osseointegration capacities of new implant surface treatments. We describe here a new method, based on matrix-assisted laser desorption ionization-mass spectrometry (MALDI-MS), for quantifying proteins adsorbed on titanium surfaces fully identical to these designed for implantology. The key step of this method is a new MALDI-MS sample preparation allowing the adsorbed proteins to be removed from the surface and to be homogeneously dispersed in the matrix crystals. The adsorption of a model protein (lysozyme) on two titanium surfaces (polished and sandblasted) was studied in order to evaluate the method. The absolute MALDI-MS intensity was shown to vary linearly with the amount of adsorbed lysozyme. After dipping the titanium surfaces for different times in lysozyme solutions at different concentrations, the maximum amount of adsorbed lysozyme was measured by MALDI-MS and was shown to correspond to a lysozyme monolayer, which is consistent with results described in the literature.

Adsorption↗

[Trauma in the anterior tooth area of the youthful dentition from the surgical viewpoint].

A choice of treatments is available for traumatised anterior teeth. Apicoectomy combined with pin insertion is recommended for fractures of the middle or apical part of the tooth, or in cases of loss of the whole tooth single implants. In many cases which previously did not appear to be amenable to treatment it is today possible to preserve the damaged teeth at least over a longish period.

Child↗

[Scanning electron microscopic research on the clinical use of interdental stripping].

The morphology of approximal enamel that has been stripped for therapeutic reasons was evaluated under the scanning electron microscope (SEM) twelve weeks and one year after treatment. In part one of the study the teeth were extracted before evaluation, in the second part replica were taken. For comparative reasons the morphology of the natural approximal enamel surface was evaluated under the SEM, too. After twelve weeks the edges of the furrows were seen to be smoother and plaque accumulations were found in the depths of the furrows. One year after there was found essentially no difference. In some of the specimens there was found a certain levelling of the edges in the approximal contact area, but not in the cervical region of the artificially abraded tooth surface. The natural enamel surface of the contact area showed excavations of similar size as the furrows that remain after stripping and finishing. But our study shows that the therapeutic approximal abrasion leaves furrows in the cervical region that even after one year had not undergone repair. The question is discussed, if thus predispositions for periodontal pathologies and caries could be created.

Bicuspid↗

[The Tübingen implant within the scope of adult orthodontic treatment].

Prior to the replacement of a missing tooth with an implant the adult dentition, orthodontic treatment can be carried out to widen the space mesio-distally, correct the axial inclination of the neighbouring teeth and safeguard the anterior overbite. Implantation is not possible if, as a result of orthodontic treatment the gap cannot be widened to a minimum of at least 6 mm, if the alveolar bone is not thick enough in the vertical dimension or if the implant does not have sufficient space in the oro-vestibular direction.

Adolescent↗

[Space closure after anterior tooth loss due to trauma].

The orthodontic treatment of space closure after loss of anterior teeth due to trauma asks not only for a dental movement but for careful consideration. These depend on various factors such as age, tooth shape, tooth size, extent of the traumatic damage and the present malocclusion. The possibilities and limits of an orthodontic treatment have to be estimated to allow a correct decision for each patient, whereby some compromise has to be accepted. This is demonstrated with two examples.

Adult↗

New technique for semipermanent replacement of missing incisors.

An investigation was carried out to study the efficiency of a new technique for semipermanent replacement of missing incisors. A flexible system allowing slight physiologic movement of the bridge units was created by bonding an acrylic tooth to the abutments by means of three orthodontic wires, as shown in Figs. 9 to 11. Between June, 1981, and December, 1982, fifty-three bridges of this type were inserted in a sample that was nonselected relative to overbite and overjet. It comprised fifty-one persons 10 to 22 years of age (mean, 16; SD, 3.9). During an observation period of 5 to 22 months (mean, 15; SD, 4.8) ten bridges came loose, giving a failure rate of 18.9% for the whole sample. All the loosened bridges were replacements for missing maxillary central incisors. The thirteen bridges replacing missing maxillary lateral incisors and two bridges inserted in the mandible functioned without problems. There was no correlation between failure rate and overjet and overbite. However, the functional occlusion was of importance. If there was antagonistic contact with the pontic during functional movements, the failure rate was 57.1%. If there was no such contact, however, the failure rate was only 5.4%. This difference was statistically significant. Accumulation of plaque was significantly higher around the abutments than on contralateral surfaces. However, no significant differences in gingival health were recorded. In two persons, dental caries was recorded on the abutment surface facing the pontic.(ABSTRACT TRUNCATED AT 250 WORDS)

Acrylic Resins↗