Left atrial thrombi, transient ischemic attacks, and atrial fibrillation.
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Recent advances in TIA research provide emergency physicians a new understanding of the disease process. Untreated or under-treated patients with TIA are at significant risk. Prompt and thorough evaluation must be undertaken to prevent devastating harm to this group of patients. This is truly a paradigm shift for many physicians, and one area in which emergency physicians lead in education and patient advocacy. The authors wish to acknowledge Dr. Stewart Wright, Dr. Alex Schneider, and Dr. Dawn Kleindorfer for their expert review, and Amy Hess for her assistance in the preparation of this manuscript.
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BACKGROUND: The etiology of stroke or transitory ischemic attack (TIA) remains frequently unknown. While paroxysmal atrial fibrillation (PAF) is often suspected, its presence remains difficult to establish. Therefore, we investigated the occurrence of PAF episodes in such a population using a long-term automatic cardiac event recorder. METHODS: We prospectively investigated 60 consecutive subjects admitted in our university hospital for stroke (n=44) or TIA (n=16), adding long-term automatic cardiac event recorders, with a target duration of 4 days, to standard investigations, which included 12-lead ECGs and 24-hour Holter recordings. RESULTS: In 28 patients no etiology was found for their stroke or TIA. However, one or more than one PAF episode was found in 4 of them (14.3%) using the long-term automatic event recorder. In the 32 remaining patients, 8 presented with PAF, and this was considered as the cause of their stroke. In both groups, AF was paroxysmal. The PAF episodes' duration went from 1 to 96 hours (mean +/- standard deviation, 18 hours and 30 minutes+/-30 hours). CONCLUSIONS: Patients suffering PAF episodes after ischemic stroke or TIA were statistically less often recognized using the 24-hour Holter ECG recording alone than the R-Test Evolution alone.
Stroke is the third leading cause of death in the United States, killing nearly 157,000 people a year with an estimated society cost of dollar 58 billion in 2006. A large percentage of ischemic strokes is secondary to extracranial carotid and vertebral arterial disease. While digital subtraction angiography has traditionally been used for the initial evaluation of the degree of stenosis, noninvasive imaging has moved to the forefront in the extracranial arterial evaluation. The importance of understanding the imaging techniques, findings, interpretation, artifacts, and pitfalls is essential to appropriate patient management.
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