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PubMed1988

Verbal and abstract designs paired associate learning after unilateral temporal lobectomy.

The combined use of a new abstract designs Paired Associates test with the Verbal Paired Associates test of Form 1 of the Wechsler Memory Scale was investigated with respect to eliciting material specific memory deficits after unilateral temporal lobectomy. Although the verbal test differentiated between the memory ability of these two groups more clearly than the abstract designs test, the effectiveness of looking at the difference between total scores on the two tests was demonstrated. The two tests produced similar levels of performance in control subjects.

Analysis of Variance↗
PubMed1981

Age, imagery, and practice in paired-associate learning.

Elder and college-aged subjects performed a series of paired-associate tasks designed to investigate age differences in the use of mnemonic imagery as a strategy in verbal learning. Subjects were tested on three occasions at two-week intervals. Two ten-pair lists of concrete-noun paired associates were learned at each session. Standard (no-imagery), self-generated, and experimenter-provided imagery instructions were used. Results indicated that imagery instructions are quite beneficial for elders in the short run. However, elders tended not to use the strategy effectively after a two-week interval unless reminded to do so. Results also indicated that elders were capable of generating useful learning strategies on their own when given sufficient experience with the task.

Adolescent↗
PubMed1990

Associative learning and memory for an antinociceptive response in the spinalized rat.

Prior research suggests that associative and memorial processes can modulate the activation of the endogenous antinociceptive systems. It has been generally assumed that forebrain systems play an essential role in mediating the impact of these processes. The present experiments explored whether the behavioral effects indicative of associative and memorial processes can be obtained in spinalized rats. Experiment 1 demonstrated that a conditioned nonopioid antinociception can be established after rats have experienced a spinal transection at the level of the 2nd thoracic vertebrae. Experiment 2 showed that a postshock distractor can speed the decay of shock-induced antinociception in the spinalized rat. These findings suggest that the circuitry needed to obtain associative and memorylike effects is present within the spinal cord.

Animals↗
PubMedDate not supplied

Roles of the qualities and locations of stimuli and responses in simple associative learning. The quality-location hypothesis.

The Quality-Location Phenomenon is defined by the previous research of Lawicka (1964 and 1969) in which dogs easily learn go/no-go tasks to differences in stimulus quality and go-left/go-right tasks to differences in stimulus location whereas the opposite pairings of tasks and stimulus attributes are difficult to learn. The Lawicka-Konorski explanation in terms of drive differentiation and response selection is described, and a new hypothesis, the Quality-Location Hypothesis, is offered. This hypothesis states that the quality of a stimulus best serves as a cue for the quality of a response, whereas the location of a stimulus best serves as a cue for the location of a response. The evidence for the hypothesis is reviewed, and experimental considerations for its evaluation are mentioned.

Animals↗
PubMed1995

Dissociation of behavioral and neural correlates of early associative learning.

Wistar rat pups were trained in an olfactory associative conditioning task on postnatal Day 6, 12, or 20. The training consisted of 20 pairings of a novel odor (peppermint) with footshock (1.5 mA, 1 s) with an intertrial interval of 3 min. Additional pups were trained in either unpaired or naive control conditions. On the day following training, pups were either tested for their behavioral response to the conditioned odor in a two-odor choice test, or injected with 14C-2-deoxyglucose and exposed to the odor for examination of olfactory bulb neural responses to the odor. The results demonstrate that, although pups at all ages learned to avoid the odor, only pups trained during the first postnatal week had a modified olfactory-bulb glomerular-layer response to the odor. These results suggest that although olfactory memory is correlated with modification of olfactory bulb glomerular layer function in newborns, these changes are not required for normal memory in older pups.

Aging↗
PubMed1985

Intact verbal paired-associate learning in alcoholics.

Evidence for impaired verbal learning/memory in alcoholics is inconsistent. In part, this may be due to variations in task parameters such as difficulty level. The latter was varied in a paired-associate paradigm with 60 chronic male alcoholics abstinent 1 month and 60 nonalcoholic matched controls. Each subject was presented four lists with seven pairs of stimulus-response combinations of word meaningfulness of high-high, low-high, high-low and low-low values. The more difficult lists resulted in greater errors for both groups, but the predicted relative impairment of alcoholics with more difficult material did not occur, nor did the groups' learning curves differ. Under our experimental conditions, rote associative learning either remains intact or recovers satisfactorily with 1 month of abstinence in alcoholics. The results emphasize the importance of methodological variables and suggest restrictions on current generalizations about cognitive impairment in alcoholics.

Adult↗