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PubMedDate not supplied

[The inductive approach in the routine laboratory diagnosis of thyroid dysfunction].

The method for defining strategy for thyroid function laboratory testing is presented in this study. In order to accomplish this task an available software, ASSISTANT Professional, was used. The strategy is generated by induction from routine data, using the method of minimizing entropy. Each of 1002 patients was described by 15 attributes and thyroid function status (euthyreosis, hyperthyreosis, hypothyreosis). Seventy per cent of the patients were chosen at random for generating and 30% for testing the strategy. The result is the decision tree or a set of decision rules. Absolute prognostic accuracy is estimated to 96% and relative to 90.16%.

Adolescent↗
PubMedDate not supplied

[Laboratory diagnosis of deep mycoses: generalities].

The mycological, immunological and histological laboratory techniques in deep mycoses are of variable interest according to the responsible fungus. If direct exam is generally possible anywhere, and very valuable in some affections, immunological diagnosis is quite often dependent of a highly specialized laboratory. As injured tissues can be transported at a long distance, with some cares and precautions, histological exams are of great interest, taken into consideration the difficulty of direct as well as indirect exams.

Fungi↗
PubMed1987

Laboratory diagnosis and characterization of renal disease in horses.

Laboratory evaluation of renal function in horses has advanced dramatically in the last 10 years largely as a result of the interest generated by the creative approach to diagnostic indices taken by Brobst, Traver, Coffman, and others. Some methods of assessing renal function discussed here are clearly outside the scope of a practice environment but are available in referral hospitals for use in difficult or unusual cases. Other methods described, such as calculation of fractional excretions and urine to serum creatinine ratios, are accessible and readily interpreted by the veterinary practitioner. These diagnostic methods should help in the early identification of renal disease in horses and therefore should allow veterinarians the option to treat renal disease before renal failure is advanced. In addition, practitioners may be able to offer more informed prognoses after a more complete evaluation of renal function.

Animals↗
PubMed1984

Laboratory diagnosis of Mediterranean spotted fever by immunofluorescent demonstration of Rickettsia conorii in cutaneous lesions.

Indirect immunofluorescent staining was performed on cryostat sections of skin biopsy specimens from 21 patients. In six of the 11 cases finally diagnosed as Mediterranean spotted fever, coccobacillary forms of Rickettsia conorii were identified in these sections. A factor recognized as contributing to false-negative results was prior treatment with tetracycline. No false-positive results were obtained for 10 patients whose final diagnosis was not Mediterranean spotted fever. This laboratory test can aid in the early diagnosis of severe and atypical forms of Mediterranean spotted fever.

Adolescent↗
PubMed1986

Viral isolation versus immune staining of infected cell cultures for the laboratory diagnosis of herpes simplex virus infections.

The Difco Laboratories Cellmatics kit, an immune staining method for the detection of herpes simplex virus after amplification in culture, was found to be 94.6% (138 of 146) sensitive and 100% (302 of 302) specific. However, conventional culturing detected 10 (6.4%) additional viruses that were not herpes simplex. For a full-service diagnostic laboratory, viral isolation is important.

Animals↗
PubMed1990

[New approaches in laboratory diagnosis of osteoarthritis].

The article elucidates the new laboratory tests for chronic joint diseases, with special attention to quantitative and qualitative serum markers for metabolic and immunologic processes. The assays include the quantification of keratan sulphate, hyaluronan and beta-D-xylosyltransferase in serum and pyridinolin in serum and urine as markers for cartilage catabolism, as well as the detection of autoantibodies to cartilage matrix and cell components and cartilage-directed T-cell reactions in the patients. Taken together, these assays represent models for future laboratory diagnostic tools for the characterization of arthritic diseases. So far, however, it remains unclear whether they will prove to be adequate assays for the practicing physician.

Autoantibodies↗
PubMed1991

Quality control in the laboratory diagnosis of tuberculosis.

The study was conducted in 4 hospital laboratories to assess the value of smear re-examination, duplicate smear and culture in quality control in the diagnosis of pulmonary tuberculosis. In each hospital 1 to 3 sputum specimens were collected from each suspect and examined by the Ziehl-Neelsen method. Smears along with corresponding specimens were sent to the reference laboratory for re-examination and examination of fresh duplicate smears and culture. A total of 994 specimens plus 23 known negative and 23 known positive controls were analysed. For each assessment method, both over-diagnosis and underdiagnosis were indicated with under-diagnosis being a more common problem in the four hospital laboratories. The limitations of these assessment methods are presented.

Evaluation Studies as Topic↗
PubMed2003

Laboratory diagnosis.

Explore the source record for details and available documents.

Clinical Laboratory Techniques↗